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Nestin-expressing cells turn into a specific type of skin cell in hair follicles during development and in adults.

Nestin marks cells that can become a specific type of skin cell in hair follicles of both developing and adult mice.

Valproic acid can cause a rare allergic reaction leading to fluid around the lungs and heart, which is treatable by changing medication.

Pranlukast and mirabegron may work as new diabetes drugs.

The weight loss drug Orlistat can cause liver damage and should be used with caution, especially in those with liver or kidney issues.

A 90-year-old woman's hand lesion was a rare, aggressive skin cancer treated successfully with surgery.

A 54-year-old man with painful skin blisters and fever was diagnosed with Sweet syndrome and successfully treated with corticosteroids.

A 5-year-old girl with a rare skin disorder was effectively treated with skin creams instead of oral medication.

A 16-year-old girl's skin rash was likely caused by an infection and improved with topical steroids.

Azathioprine can cause severe blood issues and hair loss, needing careful monitoring and possible discontinuation.

Understanding drug interactions, side effects, and patient-specific factors is crucial for effective dermatological care.

Women with PCOS often have metabolic issues like insulin resistance and a higher risk of diabetes and abnormal lipid levels.

Women with PCOS often have insulin resistance, abnormal lipid levels, and a higher risk of diabetes and heart disease; lifestyle changes and medication like metformin can help manage these risks.

Metformin is safe in early pregnancy for women with PCOS and may reduce certain risks.

Finasteride significantly increases scalp hair and prevents hair loss in young and middle-aged men.

The 2003 consensus updated PCOS diagnosis criteria and highlighted increased risks of diabetes and heart disease for those affected.

The 2003 consensus updated PCOS diagnosis criteria and linked PCOS to higher risks of diabetes and heart problems, recommending lifestyle changes to lower these risks.

Experts agree that PCOS affects women's health in complex ways, but more research is needed to understand and treat it effectively.

The document concludes that PCOS is a complex disorder caused by both genetic and environmental factors, affecting women's health in various ways, and requires personalized treatment.

Polycystic ovary syndrome is a complex condition that affects women's mental, reproductive, and metabolic health throughout their lives.

Off-pump heart surgery reduces complications without affecting survival rates compared to on-pump surgery.

Doxil is an effective, modified chemotherapy drug with a unique toxicity profile and shows promise in treating certain cancers.

Epithelial stem cells are crucial for tissue renewal and repair, and understanding them could improve treatments for damage and cancer.

Testosterone therapy improves physical function, strength, and body composition in older men with low testosterone levels.

Changing the environment around stem cells could help tissue repair, but it's hard to be precise and avoid side effects.

The hypothesis suggests that PCOS may start early in life due to genetic and environmental factors, influencing future reproductive and metabolic problems.

Improving artificial vascular grafts requires better materials and surface designs to reduce blood clotting and support blood vessel cell growth.

Targeting colon cancer stem cells might lead to better treatment results.

Understanding phenotypic plasticity is crucial for developing effective cancer therapies.

The guidelines suggest lifestyle changes, diet adjustments, and personalized medication to manage dyslipidemia and reduce heart disease risk.