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Finasteride treatment changes Cx43 in rat testes, possibly causing fertility issues.

Prolactin and TGF-β receptor blockers might help treat hair loss.

Herbal solution improves hair diameter and density more than 5% minoxidil for androgenetic alopecia.

Minoxidil does not work to inhibit lysyl hydroxylases in newborn mouse lungs.

Gut flora changes could potentially indicate depression, but more research is needed.

Aspergillus niger culture creates two finasteride derivatives with enzyme-inhibiting effects.

Hormonal therapy is effective for treating acne in adult women, especially with signs of high androgen levels.

Any drug can cause skin reactions, but antibiotics, NSAIDs, and psychotropic drugs are more common, with some reactions being life-threatening.

Pica disorder in central Iraq is mainly found in females and is linked to low iron levels; treatment with iron improves most patients.

AP-2α and AP-2β proteins are essential for healthy adult skin and hair.

Researchers found a genetic link for hereditary hair loss but need more analysis to identify the exact gene.

Antiandrogens and androgen inhibitors like spironolactone, finasteride, and dutasteride can treat hair loss and skin conditions, but they have risks and side effects, including potential harm to pregnant women and risks of cancer and heart issues. Herbal remedies also have antiandrogenic effects but lack safety validation.

Platelet-Rich Plasma (PRP) therapy can effectively treat various hair loss conditions, improve hair count, thickness, and density, and potentially speed up results when combined with surgical techniques.

Alopecia Areata is an unpredictable autoimmune hair loss condition with limited and variable treatment effectiveness.

The document concluded that FDA-approved treatments like minoxidil and finasteride are effective for hair loss, while the effectiveness of natural remedies and other non-approved treatments is not well-supported by evidence.

UK medical students lack dermatology education, liver biopsy patients with risk factors show more fibrosis, and certain fungi resist drugs due to melanin; genetics may influence female hair loss.

Storing hair follicles in a special buffer with certain inhibitors can increase hair growth and improve transplant results.

The document concludes that better targeted treatments are needed for wound healing, and single-cell technologies may improve cell-based therapies.

PCOS is a complex condition with major health impacts, needing more research for better diagnosis and treatment.

Terazosin and finasteride effectively treat BPH, but combining them adds no extra benefit.

Vitiligo is a skin condition causing white spots, more common in women, often starts before age 20, and can affect mental health.

The European Society of Endocrinology advises individualized long-term management for PCOS, focusing on lifestyle changes, accurate diagnosis, and treatments for associated health risks and symptoms.

Natural products in cosmetics are beneficial for skin and hair care with low toxicity.

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

Testosterone is important for men's sexual function, may help some women's sexual desire, while other hormones and neurotransmitters also play complex roles in sexual behavior.

Cushing's syndrome can cause serious health problems, and early treatment is crucial, but some issues may remain after treatment.

The bulletin provides guidelines for diagnosing and managing PCOS, suggesting weight loss, hormonal contraceptives, and diabetes screening, with clomiphene for infertility and various treatments for excess hair.

The conclusion is that certain cell interactions and signals are crucial for hair growth and regeneration.

The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.

Some drugs can cause rare but potentially deadly skin reactions, and early treatment and avoiding the drug again are key.