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Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.

The same genetic mutation in Sjögren-Larsson syndrome can lead to different levels of severity, suggesting other factors influence the symptoms.

Enzymes are classified into six types and are essential for many biological processes, with only a few targeted by drugs.

Some people experience lasting sexual, psychological, and sleep problems after using finasteride or SSRI antidepressants, possibly due to similar underlying causes.

New treatments for hair loss should target eight main causes and use specific plant compounds and peptides for better results.

Congenital Adrenal Hyperplasia is a rare inherited disease causing hormone imbalances, affecting growth, fertility, and heart health, diagnosed through blood tests and treated with medication and lifestyle changes.

Different skin cells process testosterone differently, and certain drugs can change this process, possibly helping treat acne and hair loss.

Finasteride inhibits enzyme activity in rhesus macaques, suggesting they're useful for evaluating similar drugs.

Certain 4-azasteroids are effective at blocking the enzyme that processes testosterone in human skin and could help treat acne, excessive hair growth, and male pattern baldness.

The study found that two enzymes linked to hair loss are located in different parts of the scalp, supporting a common treatment's effectiveness.

Finasteride effectively blocks rat enzymes, but with varying methods and strength.

Gene mutations can cause problems in male genital development.

Antiandrogens can help treat skin conditions like acne and excessive hair in women when used carefully.

People with hair loss have more androgen receptors and enzymes in certain follicles, with men and women showing different patterns.

Male pattern baldness involves genetics, hormones, and needs better treatments.

Fadrozole and finasteride change gene expression related to sex hormones and thyroid hormones in frog larvae development.

Antiandrogens, particularly flutamide and CPA, are most effective for treating hirsutism, with long-term use needed for best results.

The protein StAR is found in 17 different organs and can affect hair loss and brain functions, but its full role is not yet fully understood.

The conclusion suggests that prostate cancer should be classified by castration status and that new therapies targeting androgen receptor signaling show promise.

Ketoconazole shampoo with finasteride improves hair density in men with hair loss.

Dermatologists should screen for and manage psychological issues in patients with skin conditions to improve their quality of life.

Sex hormones affect hair and feather growth and may help manage alopecia and hormone-dependent cancers.

Progesterone byproduct 5αP stimulates mammary tumor growth, but finasteride can suppress it.

Plant-based remedies may treat hair loss by reducing inflammation and improving insulin resistance.

The conclusion is that while oral contraceptive pills are effective for PCOS-related high androgen levels, new treatments with fewer side effects are needed.

Testosterone helps human pancreatic cells increase insulin release.

COX-2 levels change during the hair cycle and affect skin and hair growth.

Glioblastoma cells can make androgens, which might help the tumor grow.

The study created a new method to test drugs that affect hormone processing in skin.

The study concluded that changing the culture conditions can cause sika deer skin cells to switch from a flat to a 3D pattern, which is important for creating hair follicles.