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Gonadal hormones significantly affect the severity of alopecia areata in mice.

Metformin helps manage diabetes, PCOS, and weight in kids but needs more research for long-term safety.

The conclusion is that the best initial treatment for hirsutism is usually oral contraceptives, with the addition of antiandrogens or insulin sensitizers if needed, and topical eflornithine or laser treatments as supplementary options.

Local testosterone treatment improved sexual desire in a female with fragile X syndrome.

A protein from certain immune cells is key for new hair growth after skin injury in mice.

A simple screening method found that 6.3% of women in a semiurban area in Sri Lanka have polycystic ovary syndrome, with most showing menstrual irregularities.

The document concludes that accurate diagnosis and personalized treatment are important for skin problems in women with PCOS.

Antiandrogens, particularly flutamide and CPA, are most effective for treating hirsutism, with long-term use needed for best results.

Excess male hormones in postmenopausal women can cause health issues and increase the risk of heart disease and diabetes; treatment depends on the cause.

Gene mutations can cause problems in male genital development.

High-dose dutasteride reduces PMDD symptoms by stabilizing neurosteroid levels.

Hormonal treatments can help with acne, especially in women, by lowering androgen levels or blocking their effects.

Menopause reduces skin collagen and elasticity, and while estrogen therapy can help, its risks require careful consideration.

Hormonal treatments can help with acne but are not the first choice due to side effects and the need for careful patient selection.

Low-dose gonadotropin treatment is effective for infertility in women with PCOS, leading to high ovulation rates and comparable pregnancy rates with fewer complications.

PCOS in teens is hard to diagnose, linked to genetics and lifestyle, and managed with weight loss and medication.

Activin B improves wound healing and hair growth by helping stem cells move using certain cell signals.

Gonadal dysgenesis, like Turner's and Klinefelter's syndromes, negatively affects bone health, but hormone treatments can help.

Some plant-derived compounds may help with hormonal conditions, but more research is needed to confirm their effectiveness.

Most skin changes during pregnancy go away after giving birth.

Future osteoporosis treatments should focus on increasing bone growth, with many promising options available.

Antiandrogens have important biological effects, but more research is needed to understand them fully and compare their effectiveness and side effects to other treatments.

The document says that understanding the causes of PCOS is important for treatment, especially in distinguishing the syndrome from just having cystic ovaries, and that losing weight is key for obese women with PCOS.

Testosterone therapy can help improve mood, sexual function, and bone health in women with low androgen levels, but more research is needed to establish safe and effective guidelines.

Treating excessive hair in women requires a holistic approach, including medical, aesthetic, and emotional support.

Women with greater androgen sensitivity respond better to finasteride for hair loss.

CAH is a genetic disorder affecting cortisol production and causing hormonal imbalances, with treatment and diagnosis varying by form and symptoms.

Obstetrician/gynecologists can diagnose and manage female hair loss with careful history taking and examination.

5α-reductase inhibitors like finasteride may not be effective or safe for transgender individuals, and more research is needed.

Hormonal therapies, like flutamide and cyproterone acetate, are safe and effective for treating adult women's acne, especially those with hormone imbalance or resistant acne.