20 citations
,
April 2009 in “Cell Biology International” This study demonstrates that bulge KSCs from hair follicles can transdifferentiate into corneal epithelial-like cells under specific conditions, which could support bioengineered cornea development.
44 citations
,
April 2017 in “Genes & development” This study identified hair shaft progenitors in the matrix that regulate hair growth and pigmentation by creating a niche dependent on stem cell factor, implicating KROX20+ cells in these processes.
April 2016 in “Plastic and reconstructive surgery. Global open” This abstract catalogs resources from the American Society of Plastic Surgeons but presents no research findings.
1 citations
,
October 2019 in “Journal of Craniofacial Surgery” In this study, 3D planned resection and reconstruction for skull defects after resection of cSCC with bony invasion led to accurate procedures, though patient-specific factors should guide treatment decisions.
January 2025 in “bioRxiv (Cold Spring Harbor Laboratory)” This study explored how T cells interact with hair follicles in primary cicatricial alopecias by using spatial transcriptomics across mice, dogs, and human samples, revealing specific communication pathways and potential drug targets like CFD and S100A8/9 for future therapeutic research.
October 2024 in “Journal of the Endocrine Society” This case report describes a patient with an ovarian steroid cell tumor that initially presented as non-classical adrenal hyperplasia, emphasizing the difficulty in differential diagnosis with hyperandrogenism and the importance of close clinical monitoring.
June 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that the HoxC gene cluster is crucial for the development of hair and nails in mice, with key regulation by two mammalian-specific enhancers.
November 2024 in “Frontiers in Endocrinology” This study used a novel extraction method to detect and measure mineralocorticoids and glucocorticoids in hair follicles, concluding these steroids may serve as effective biomarkers for diagnosing conditions related to steroid excess or deficiency, such as Cushing’s syndrome and congenital adrenal hyperplasia.
10 citations
,
January 2011 in “Journal of biomedical optics” This study found that optical coherence tomography provides highly reproducible and less variable measurements of hair shaft thickness compared to standard light microscopy, offering a promising noninvasive tool for clinical practice.
5 citations
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April 2011 in “The Lancet” This case report describes a 60-year-old man with a rare 46, XX karyotype who presented with cerebellar infarct and polycythaemia, leading to further endocrine investigations after adrenal gland enlargement was found.
85 citations
,
January 2014 in “Hormone Research in Paediatrics” This study found that hair cortisol concentrations can be reliably measured in healthy children and generally increase with age, unaffected by gender, puberty, or hair care practices.
151 citations
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December 2004 in “Annals of the New York Academy of Sciences” This review discusses nonclassical 21-hydroxylase deficiency as the most common autosomal recessive disorder in humans and highlights the effectiveness of glucocorticoid treatment in reversing related symptoms.
January 2024 in “Animals” This study suggests that the transcription factors SP1 and KROX20 regulate CUX1 gene's effect on the proliferation of ovine dermal papilla cells in vitro.
May 2021 in “Journal of the Endocrine Society” This case study reports a patient with ACTH-driven cortisol secretion 14 years after adrenalectomy, suggesting possible residual adrenal tissue or extra-adrenal steroid synthesis, challenging the need for lifelong steroid replacement.
62 citations
,
March 2011 in “European journal of endocrinology” This study found that parents identified with cryptic NCCAH through genetic testing are mostly asymptomatic but may experience temporary female infertility and require glucocorticoid stress coverage in specific circumstances.
28 citations
,
March 2014 in “Biological reviews/Biological reviews of the Cambridge Philosophical Society” This study introduces the multiple papillary centres model, offering a new explanation for hair twisting by combining known hair morphology features with differential growth rates caused by dermal papillae.
July 2011 in “Neurotoxicology and Teratology”
August 2009 in “Mechanisms of Development” Adult hair follicle cells can create new hair follicles from corneal cells with the right support.
13 citations
,
July 2009 in “Pediatrics in Review” This review discusses the diagnosis and treatment of 21-hydroxylase deficiency in congenital adrenal hyperplasia and emphasizes the need for earlier detection and proper management; it reports no clinical results.
This study found that the Lim-homeodomain transcription factor Lhx2 regulates Sonic Hedgehog signaling during early retinal neurogenesis in mice by controlling the expression of pathway genes in retinal progenitor cells.
6 citations
,
March 2021 in “Frontiers in surgery” This case report describes a 64-year-old woman with hirsutism who was found to have a borderline adrenocortical oncocytoma, successfully treated with adrenalectomy.
45 citations
,
May 2012 in “CRC Press eBooks” The book helps doctors better understand and treat hair disorders due to gaps in their training.
April 2021 in “Journal of Investigative Dermatology” Krox20 is crucial for hair growth and maintaining skin stem cells.
May 2026 in “The Knowledge Bank (The Ohio State University)” This study observed significantly higher hair cortisol concentrations in foals compared to mares, with a strong positive correlation between the two, suggesting that hair cortisol can reflect maternal and fetal cortisol exposure during the last trimester of gestation in horses.
July 2019 in “Dermatologic Surgery” This abstract provides contact information for François Kuonen at the Lausanne University Hospital Center and reports no new research findings.
11 citations
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June 2001 in “British Journal of Dermatology” This study found that asynchronous differentiation in human anagen hair follicles involves specific localization of c-Myc and interrelated genes Max and Bin1 along the inner root sheath.
February 2024 in “Journal of Dermatological Science” This study examined the formation of acquired curved hair and found that the fusion of hair matrix cells during follicle regeneration contributes to asymmetric follicle shapes and curved hair, potentially linked to changes in type IV collagen and protein expression levels.
January 2025 in “Haematology International Journal” This study describes a functional disorder in the ovary, known as stromal hyperplasia, characterized by the proliferation of ovarian stroma and luteinization of stromal cells, which is linked to excessive androgen production and elevated testosterone levels.
27 citations
,
July 1993 in “The journal of investigative dermatology/Journal of investigative dermatology” 28 citations
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September 2011 in “Stem Cell Reviews and Reports”