December 2023 in “Frontiers in endocrinology” This review explores the role of hyperandrogenism, including adrenal-derived 11-oxygenated androgen, in the development of polycystic ovarian syndrome and discusses potential therapeutic strategies targeting androgen excess, without reporting new clinical results.
July 2020 in “Vestnik urologii” This review examines the contentious issue of post-finasteride syndrome linked to 5-alpha reductase inhibitors and reports mixed findings on its sexual, physical, and psychological effects; the authors call for more rigorous studies.
11 citations
,
January 2019 in “Sexual Medicine” This study found that among MtF transgender individuals, those with early-onset gender dysphoria exhibited differences in age at surgery, sexual orientation, and sexual activity compared to those with later-onset dysphoria.
55 citations
,
August 2003 in “Ultrasound in Obstetrics and Gynecology” This study suggests that ultrasound and color Doppler analyses may enhance the differential diagnosis of GnRH-dependent precocious puberty in girls with premature breast development or pubic hair growth.
57 citations
,
July 2016 in “The Journal of Sexual Medicine” This study concluded that 5α-reductase inhibitors were linked to increased sexual dysfunction in men with benign prostatic hyperplasia, but not in men with androgenetic alopecia.
1 citations
,
June 2014 in “L Endocrinologo” Finasteride can cause lasting sexual and mood issues even after stopping the drug.
2 citations
,
January 2023 in “Sexual Medicine” This study found that the MTCK, a masturbation aid, significantly improved intravaginal ejaculation latency time and some related sexual function scores in men with premature ejaculation after 8 weeks of use.
2 citations
,
February 2022 in “Pakistan Armed Forces Medical Journal” This study found that women with PCOS reported significant appearance-related distress and social anxiety, especially in social settings.
February 2024 in “International journal of health, medicine and nursing practice” This study suggests that improving public awareness and educational initiatives about polycystic ovary syndrome could lead to earlier diagnoses and treatments, enhancing women's quality of life while reducing healthcare costs.
21 citations
,
February 2016 in “Reproductive Biomedicine Online” This review examines how genetic variants associated with polycystic ovary syndrome affect reproductive success differently in men and women, supporting the theory that intralocus sexual conflict may explain its persistence.
34 citations
,
February 2013 in “The Journal of Clinical Endocrinology and Metabolism” This study estimates the prevalence of hyperandrogenic states in late adolescent and young females, revealing that these disorders often begin at a young age.
5 citations
,
January 2019 in “cIRcle (University of British Columbia)” This research observed that women with PCOS may improve insulin resistance and reduce hyperandrogenism by increasing fiber and magnesium intake, and face higher anxiety symptoms potentially linked to societal appearance expectations.
This review discusses the evidence for testosterone therapy to improve sexual desire in women after bilateral oophorectomy and provides prescribing recommendations for nurse practitioners, but it reports no new clinical results.
36 citations
,
May 2011 in “The Journal of Clinical Endocrinology & Metabolism” Treatment with a hormone agonist can reduce excess male hormones in postmenopausal women without surgery.
This paper addresses diagnostic criteria and treatment options for polycystic ovary syndrome, emphasizing lifestyle changes and combination oral contraceptives as primary management strategies, but it reports no new clinical results.
October 2025 in “Journal of the Endocrine Society” This case report illustrates a rare instance of mixed germ cell tumor in the pituitary with hyperandrogenism, emphasizing the importance of thorough examination and hormone evaluation in identifying hormonal dysfunctions.
December 2019 in “Reactions Weekly” Man stopped medications due to sexual side effects, found relief with prostatic artery embolisation.
This review discusses the pilocutaneous syndrome of menopause, associated with skin and hair changes due to estrogen decline, and highlights an unmet need for recognition and targeted treatment.
16 citations
,
February 2014 in “Iranian Red Crescent Medical Journal” This qualitative study revealed that women with PCOS often see themselves as less feminine, affected by symptoms like excess hair and irregular menstruation, which challenged their gender roles.
23 citations
,
June 2005 in “Journal of cosmetic dermatology” This article reviews the psychosocial impacts of androgenetic alopecia on men, highlighting the importance of addressing both hair loss and associated psychological disorders for improved treatment satisfaction.
2 citations
,
May 2018 in “Diagnosis” This case report presents a rare instance of an ovarian steroid cell tumor in a 68-year-old female with virilism, which normalized androgen levels following surgical removal.
November 2017 in “International journal of family & community medicine” This case report observed that hypogonadism and cold sensation resolved in a patient after discontinuing 5-alpha-reductase inhibitors, suggesting these medications may contribute to such symptoms.
76 citations
,
November 2009 in “Medical Clinics of North America” This article reviews the hormonal and medication-related factors associated with acne development but does not present new research findings.
16 citations
,
December 2007 in “Expert Review of Pharmacoeconomics & Outcomes Research” This review discusses the impact of polycystic ovary syndrome on health-related quality of life, highlighting its negative effects which may be influenced by cultural perceptions, obesity, infertility, and menstrual issues.
11 citations
,
March 2019 in “Journal of The American Academy of Dermatology” This review identifies evidence of sexual adverse effects, particularly linked to finasteride, in men using systemic dermatologic medications but reports no new clinical findings.
May 2013 in “Journal of the ASEAN Federation of Endocrine Societies” This case study reports that a 61-year-old woman with high testosterone levels due to stromal luteoma of the left ovary experienced rapid normalization of testosterone levels after surgical removal of the tumor.
4 citations
,
May 2007 in “Oral and Maxillofacial Surgery Clinics of North America” This article reviews gender differences in planning and managing female cosmetic surgery patients and reports no new clinical findings.
March 2026 in “The Journal of Sexual Medicine” In this study, older women aged 70 and above, treated for sexual dysfunction using carefully monitored hormone therapy, reported improvements in sexual function and symptom relief, with no incidences of cancer or thromboembolic events, though some experienced breast tenderness and hair changes.
January 2025 in “JCEM Case Reports” Among postmenopausal women, this case study observed that a rare ovarian tumor called thecoma, found via MRI, was associated with high testosterone levels and symptoms of mild virilization such as hirsutism, indicating surgery as the primary treatment.
January 2024 in “JEADV clinical practice” This study reviewed research on the psychosocial effects of gender-affirming dermatology treatments in transgender populations, finding mostly positive associations but noting significant limitations and the need for more comprehensive studies to clearly understand these effects.