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Exposure to certain sex hormones can increase health risks, while some hormone therapies may offer benefits for specific conditions.

Skin aging is caused by stem cell damage and can potentially be delayed with treatments like antioxidants and stem cell therapy.

Estrogens help reduce skin aging, and SERMs might offer similar benefits without the risks of hormone therapy.

Stem cells compete for space using cell adhesion, and mutations can affect their competitive success, with implications for tissue health and disease.

Hirsutism in women is often due to hormone sensitivity and has significant psychological effects.

Testosterone and dihydrotestosterone treatments can help with penile growth in males with 5α-reductase type 2 deficiency, with dihydrotestosterone being more effective in infancy.

Targeting thyroid hormone receptor α in liver cells may help treat liver fibrosis.

Pharmaceutical care in transplantation faces challenges but has promising future opportunities for better outcomes.

Transplant success has improved with better immunosuppressive drugs and donor matching.

The current system can't fully test all combination treatments, so alternative methods and regulatory flexibility are needed.

Hormone therapies like birth control pills and spironolactone are safe and effective for treating women's adult acne.

New skin substitutes for treating severe burns and chronic wounds are being developed, but a permanent solution for deep wounds is not yet available commercially.

The document suggests a need for collaboration, better evidence, and a responsible framework to safely and effectively advance regenerative therapies to clinical use.

Proteoglycans are important for hair growth, and a specific treatment can help reduce hair loss.

Old treatments for other skin conditions showed promise for hair regrowth in mice with a hair loss condition.

Male hormones cause different growth in identical human hair follicles due to their unique epigenetic characteristics.

Keratinocytes and adipose-derived stem cells can effectively heal difficult skin wounds.

Hormonal therapies are effective for managing hair and skin symptoms in women with PCOS.

Estrogen loss during menopause worsens skin health, but hormone replacement therapy may improve it, though more research is needed.

The Multi-Organ-Chip improves the growth and quality of skin and hair in the lab, potentially replacing animal testing.

Cell-based therapies using dermal papilla cells and adipocyte lineage cells show potential for hair regeneration.

Targeted cancer therapies can cause skin side effects, which should be treated early to help patients' quality of life and treatment adherence.

Secretome-based therapies could improve hair growth better than current treatments.

The man's fatigue and erectile dysfunction were improved by treating his obesity-related low testosterone without needing testosterone replacement.

A group has developed therapies that show promise for treating cancer and various other conditions.

The conclusion is that effective cancer treatment often requires a combination of therapies, but must be carefully managed due to serious side effects and the risk of immunosuppression.

Mice with enhanced regeneration abilities may help develop new regenerative medicine therapies.

The document concludes that a complete skin restoration biomaterial does not yet exist, and more clinical trials are needed to ensure these therapies are safe and effective.

New materials and methods could improve skin healing and reduce scarring.

Human skin has multiple layers and functions, with key roles in protection, temperature control, and appearance.