56 citations,
April 1998 in “Steroids” Finasteride reduces hair loss and treats BPH without major hormone changes, but may cause sexual dysfunction.
41 citations,
March 1998 in “Archives of Dermatological Research” The enzyme that changes testosterone to a stronger form is mostly found in the part of the hair follicle called the dermal papilla.
14 citations,
May 2012 in “Endocrine Research” The same hormone can affect gene expression differently in various tissues, which could lead to new treatments for conditions like hair loss.
June 2012 in “Springer eBooks” Skin changes can indicate starvation and nutritional deficiencies in anorexia nervosa.
35 citations,
December 2009 in “Human reproduction” Metformin taken during pregnancy increases SHBG in newborns but doesn't change other hormone levels in mothers or babies.
18 citations,
May 2014 in “Menopause” A 5 mg dose of transdermal testosterone cream effectively restores testosterone levels in postmenopausal women.
62 citations,
April 2004 in “Expert Opinion on Pharmacotherapy” Finasteride effectively treats male pattern baldness, improving hair growth and density.
6 citations,
September 2005 in “Expert Opinion on Pharmacotherapy” Androgen therapy can help with symptoms like low libido in women, but more research is needed to understand its long-term safety and effects on health.
January 2003 in “Humana Press eBooks” Dihydrotestosterone and 5α-Reductase play a role in hair loss and prostate health, and finasteride can increase hair growth in men without affecting sperm production, but it doesn't work for postmenopausal women with hair loss.
59 citations,
August 1998 in “International Journal of Dermatology” Genetics and hormones cause hair loss; finasteride treats it safely.
9 citations,
March 1985 in “Head & Neck Surgery” Topical minoxidil is the most promising treatment for male pattern hair loss, but more research is needed to confirm its effectiveness and safety.
57 citations,
January 1986 in “The Prostate” The document suggests that targeting the hormone DHT could be a more effective treatment for prostate cancer than targeting testosterone.
102 citations,
July 2020 in “International journal of molecular sciences” Hormones like testosterone and estrogen significantly affect hair growth and structure.
40 citations,
January 1994 in “Skin Pharmacology and Physiology” Male hormones affect oil-producing skin cells differently based on their body location, and the drug spironolactone can reduce these effects.
Caffeine can potentially treat common hair loss by counteracting hair follicle shrinkage caused by hormones.
89 citations,
February 1993 in “Journal of Medicinal Chemistry” New compounds called benzoquinolinones may treat conditions linked to excess DHT.
28 citations,
November 2003 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” The normal human prostate does not significantly affect blood DHT levels.
3 citations,
May 2021 in “Dermatologic Clinics” The document concludes that more research is needed to understand hair loss in men and to find new treatments.
6 citations,
August 1996 in “The Journal of Clinical Endocrinology and Metabolism” MK-386 and finasteride together effectively reduce DHT levels, potentially treating acne and male pattern baldness.
6 citations,
January 2017 in “Dermato-endocrinology” ADT-G may be a useful indicator of increased androgen levels in women with acne and can be lowered with certain birth control pills.
1 citations,
October 2017 in “Elsevier eBooks” Antiandrogens can treat female hormonal conditions, but environmental ones may harm reproductive health.
December 2024 in “Research Journal of Pharmacy and Technology” Androgenic alopecia is mainly caused by DHT, and new treatments focus on hair regeneration and aging factors.
76 citations,
October 2016 in “Clinics in dermatology” Sex hormones, especially androgens, play a key role in causing acne.
3 citations,
October 1995 in “International Journal of Dermatology” Finasteride helps treat skin issues like acne and baldness by blocking testosterone conversion.
1 citations,
August 2020 in “Food Research” Plant extracts like Avicennia marina, Boehmeria nipononivea, and Camellia sinensis could potentially treat hair loss with fewer side effects than synthetic drugs.
21 citations,
August 1994 in “Clinical endocrinology” 5α-Reductase inhibitors can help treat hair loss, acne, and prostate issues by reducing DHT levels.
6 citations,
February 1996 in “Clinical Pharmacology & Therapeutics” Scale created to measure hair loss in men and women; MK-386 reduces acne; Niaspan treats dyslipidemia; minoxidil increases heart rate.
January 2021 in “HAMDAN MEDICAL JOURNAL” Finasteride treats hair loss and reduces prostate cancer risk.
2 citations,
January 2010 in “Hormone Molecular Biology and Clinical Investigation” Low dose finasteride decreases certain steroids, possibly increasing depression risk.
April 2022 in “Molecules” Teak leaf extract contains compounds that could help treat hair loss.