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Chemotherapy and radiotherapy can cause skin side effects like rashes, hair loss, and nail changes, which are usually managed with conservative treatments.

The document concludes that ERBB2 mutations are common in extramammary Paget disease and may respond to systemic treatments like cancer immunotherapy.

Intralesional chemotherapy with 5-fluorouracil and methotrexate may worsen keratoacanthoma-type skin cancer in transplant patients.

WNT10A mutations often cause ectodermal dysplasias, with males showing more tooth issues than females.

FGF5 gene mutations cause long hair in domestic cats.

The document concludes that while some organisms can regenerate body parts, mammals generally cannot, and cancer progression is complex, involving mutations rather than a strict stem cell hierarchy.

Mutations in Gasdermin A3 cause skin inflammation and hair loss by disrupting mitochondria.

Stem cells compete for space using cell adhesion, and mutations can affect their competitive success, with implications for tissue health and disease.

Mutations in Plcd1 and Plcd3 together cause severe hair loss in mice.

Keratin proteins are crucial for healthy skin, but mutations can cause skin disorders with no effective treatments yet.

The ITGB6 gene is important for tissue repair and hair growth, and mutations can lead to enamel defects and other health issues.

Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.

The document concludes that Borrelia afzelii causes a skin condition in France, a gene is linked to hair loss in Caucasian women, and various genetic mutations affect skin diseases.

The transgene likely activated an oncogene or interrupted a tumor suppressor gene, causing melanoma in mice.

Keratin mutations cause skin diseases and could lead to new treatments.

The document concludes that mouse models are crucial for studying hair biology and that all mutant mice may have hair growth abnormalities that require detailed analysis to identify.

Most adrenal cortex tumors are benign and non-secreting, but proper diagnosis and treatment are important due to the rare possibility of cancer.

Inhibiting AP-1 changes skin tumor types and affects tumor cell identity.

Inhibiting AP-1 changes skin tumor types and affects tumor cell identity.

The research shows that a gene called Wnt3 affects hair growth and structure, causing short hair and balding when overactive.

The conclusion is that proper signaling is crucial for hair growth and development, and errors can lead to cancer or hair loss.

FGF5 gene mutations cause unusually long eyelashes by affecting hair growth regulation.

Disrupting Stat3 in hair follicle stem cells greatly reduces skin tumor formation.

Future research on ectodysplasin should explore its role in diseases, stem cells, and evolution, and continue developing treatments for genetic disorders like hypohidrotic ectodermal dysplasia.

Keratin is crucial for keeping skin cells healthy and its changes can lead to diseases and affect cell behavior.

Skin lesions in Carney complex are likely caused by a specific group of skin cells that promote pigment production due to a genetic mutation.

Minoxidil showed a 30% success rate for hair growth in a study, and various skin treatments were effective, but some had limitations or side effects.

Melanocytes are crucial for skin pigmentation and can affect conditions like melanoma, vitiligo, and albinism, as well as hair color and hearing.

Lamins are vital for cell survival, organ development, and preventing premature aging.

The article explains the genetic causes and symptoms of various hair disorders and highlights the need for more research to find treatments.