September 2019 in “Journal of Investigative Dermatology” This clinical trial found that Sandalore® 1% significantly reduced hair shedding and increased hair volume and anagen hair follicles in women with telogen effluvium compared to placebo.
April 2019 in “Journal of Investigative Dermatology” This clinical trial found that topical application of Sandalore® 1% significantly reduced hair shedding and increased hair volume in women with telogen effluvium compared to placebo.
April 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” This study suggests that stimulating olfactory receptors in human hair follicles with Sandalore® increases antimicrobial activity by upregulating dermcidin production, potentially offering a novel approach for treating hair follicle diseases with bacterial issues.
15 citations
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September 2018 in “Indian Research Journal of Pharmacy and Science” This article reviews the historical and therapeutic aspects of aromatherapy, discussing its effects on psychological and physical well-being but providing no new clinical findings.
May 2024 in “International journal of medicine and psychology.” In this study, researchers analyzed the effects of 100% natural essential oils on psycho-emotional states, finding changes in brain activity, stress levels, and overall condition, suggesting a potential for self-correction programs.
May 2020 in “Authorea (Authorea)” This review discusses the diverse functions and therapeutic potential of ectopic olfactory receptors throughout the body, emphasizing their roles in various cellular processes and potential in cancer detection and therapy, but reports no new clinical results.
September 2019 in “Journal of Investigative Dermatology” This clinical trial reported that Sandalore® 1% significantly reduced hair shedding and increased hair volume and anagen HFs in women with telogen effluvium compared to placebo, supporting its potential use in hair growth treatments.
September 2019 in “Journal of Investigative Dermatology” This study reports that thermography and high-frequency ultrasound show promise as diagnostic tools for personalizing treatment plans in atopic dermatitis and psoriasis vulgaris by assessing skin lesion characteristics.
September 2019 in “Journal of Investigative Dermatology” This study demonstrated that an RO formulation significantly improved neck wrinkles after 8 weeks of application, compared to a placebo, in Japanese female subjects.
January 2025 in “Current Allergy and Asthma Reports”
4 citations
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November 2024 in “Cell Biology and Toxicology” This study suggests that targeting olfactory receptors in the lung epithelium might help treat odorant-induced asthma in cases without type 2 inflammation, as these receptors could play a role in airway sensitivity to smells.
82 citations
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September 2018 in “Nature Communications” This study found that stimulating the olfactory receptor OR2AT4 in human hair follicles with a synthetic sandalwood odorant promotes hair growth ex vivo by decreasing apoptosis and increasing IGF-1 production.
April 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” The researchers reported that DHT may reduce the inflammatory responses induced by C. acnes in androgen-sensitive human sebocyte cells, suggesting a potential link between androgens and infection in sebaceous disorders.
December 2012 in “한국피부미용향장학회지” This study suggests that aroma oils categorized by scalp type have similar chemical compositions, potentially enhancing their effectiveness in aromatherapy for scalp issues.
1 citations
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April 2019 in “Journal of Investigative Dermatology” This study concluded that the topical gel VB1953 reduced inflammatory and non-inflammatory acne lesions and resistant bacteria in patients with clindamycin-resistant acne, showing promise as an effective treatment.
1 citations
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April 2019 in “Journal of Investigative Dermatology” This study examined the safety and efficacy of dupilumab in adolescents with moderate-to-severe atopic dermatitis, finding that it was well tolerated and significantly improved symptoms over 52 weeks, with its safety profile similar to that in adults.
April 2019 in “Journal of Investigative Dermatology” This study observed that people with autoimmune blistering skin disorders report higher food intolerance rates, particularly avoiding alcohol, citrus, and spicy foods, and suggests potential dietary influences on symptom management.
10 citations
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April 2022 in “Critical reviews in food science and nutrition” This review examines the potential role of odorant receptors in human skin cells responding to flavor compounds and their implications for skin health and disease, without providing new clinical results.
4 citations
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July 2024 in “European Archives of Oto-Rhino-Laryngology” This study found that platelet-rich plasma injections significantly improved olfactory function in patients with long-lasting postviral olfactory dysfunction, suggesting potential as a therapeutic strategy.
January 2024 in “Deleted Journal” In this narrative review, essential oils like lavender, chamomile, and bergamot are identified as effective interventions for stress management, influencing emotional processes through various application methods and promoting both physical and emotional well-being.
February 2023 in “Han'gug miyong haghoeji/Journal of the Korean society of cosmetology” This study observed that using an aroma shampoo containing essential oils for 4 weeks improved hair density and number in the occipital area, unlike a general shampoo used by the control group, which led to decreased hair number and thickness in the parietal area.
December 2023 in “Gugje bogeon mi-yong haghoeji” In this study, researchers observed that aroma oil-enhanced scalp scaling significantly improved scalp conditions over 8 weeks, marked by increased water and oil content, reduced keratin and surface value, and higher satisfaction in hair-related outcomes compared to the control group.
July 2024 in “Journal of Investigative Dermatology” Linalool in fragrances may harm hair follicles and contribute to hair loss.
This chapter reports that essential oil-based therapy, or aromatherapy, poses potential benefits for managing various disorders, such as pain, psychological issues, and skin conditions, although toxicity risks necessitate careful use under professional supervision.
April 2024 in “Contribuciones a las ciencias sociales” This literature review found that combining essential oils with clay therapy can treat dandruff and seborrhea, but notes that this approach is not widely recognized, indicating a need for further research.
June 2021 in “Dépôt Institutionnel de lUniversité de Tlemcen” This survey reported that essential oils are predominantly used by Algerian women for cosmetic and medical purposes, with applications ranging from skincare to treating respiratory illnesses and other conditions.
November 2022 in “Journal of Investigative Dermatology” This study found that stimulating the olfactory receptor OR2A4/7 with cyclohexyl salicylate promoted human hair growth and increased progeny of hair follicle epithelial stem cells in an ex vivo setting.
November 2025 in “The Laryngoscope” This article reviews the use of sodium fluoride in otosclerosis management, finding limited evidence of its efficacy in preventing hearing deterioration and highlighting potential toxicity concerns.
January 2025 in “Letters in Drug Design & Discovery” This study found that ozonated olive oil exhibited antifungal activity against Trichophyton mentagrophytes, comparable to the standard antifungal terbinafine, in an in vivo rat study, suggesting it may serve as an alternative treatment for dermatophytosis.