research A Simple Non-Invasive Approach Toward Efficient Transdermal Drug Delivery Based on Biodegradable Particulate System
A new method for delivering drugs through the skin using biodegradable particles was found to be effective.
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research Expression of an Olfactomedin-Related Gene in Rat Hair Follicular Papilla Cells
FP-1 is a key protein in rat hair growth, active only during the growth phase.
research Topical Odorant Application of the Specific Olfactory Receptor OR2AT4 Agonist, Sandalore, Improves Telogen Effluvium-Associated Parameters
Sandalore® improves hair growth and quality in people with hair loss.
research Topical Sandalore, a Specific OR2AT4-Stimulating Odorant, Ameliorates Female Telogen Effluvium: Randomized, Double-Blinded, Placebo-Controlled Clinical Trial
Sandalore®, a synthetic scent, improved hair loss and satisfaction in women with telogen effluvium.
research Olfactory Receptor OR2AT4 Regulates Human Hair Growth
A certain smell receptor in hair follicles can affect hair growth when activated by a synthetic sandalwood scent.
research Symptom Profile of Patients With Post-Covid-19 Conditions and Influencing Factors for Recovery
Zinc acetate hydrate may help reduce fatigue and hair loss in post-COVID-19 patients.
research The Adenosine-Generating Ecto-Enzyme CD73 Regulates Human Hair Growth
The enzyme CD73 helps control human hair growth and could be targeted to treat hair growth disorders.
research BMP Signaling in the Control of Skin Development and Hair Follicle Growth
BMP signaling is crucial for skin and hair growth.
research Wnt Signaling Regulates Symmetry of Division of Neural Stem Cells in the Adult Brain and in Response to Injury
Wnt signaling helps control how brain stem cells divide and is important for brain repair after injury.
research Realizing the Therapeutic Potential of Neuroactive Steroid Modulators of the GABAA Receptor
Neuroactive steroids show promise for treating mental and neurological disorders by targeting GABA_A receptors.
research Transnasal Cooling: A Pandora’s Box of Transnasal Pathophysiology
Transnasal cooling could reveal new insights into various physiological conditions and may be a natural way to transfer heat from the brain.
research The Role of Neurorehabilitation in Post-COVID-19 Syndrome
Tailored neurorehabilitation programs improve life quality for post-COVID-19 patients.
research Ocular Manifestations in a Case of Kallmann Syndrome: An Interesting Case Report on Isolated Gonadotropin-Releasing Hormone Deficiency
Kallmann syndrome can cause eye issues and other health problems, requiring various treatments.
research Diffuse Idiopathic Skeletal Hyperostosis in a 33-Year-Old Woman with PCOS and Metabolic Syndrome: A Rare Scenario
A 33-year-old woman with PCOS and metabolic syndrome was unusually diagnosed with a bone condition called DISH, suggesting a possible link between these conditions.
research Effect of 5-Alpha Reductase Inhibitors in Animal Models of Parkinson's Disease
5-alpha reductase inhibitors may help protect the brain and gut in Parkinson's disease.
research MC4R Variants rs12970134 and rs17782313 Are Associated with Obese Polycystic Ovary Syndrome Patients in the Western Region of Saudi Arabia
Certain MC4R gene variants are linked to higher BMI in obese women with PCOS but do not cause PCOS.
research Consequences of Steroid-5α-Reductase Deficiency and Inhibition in Vertebrates
Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.
research New Intranasal and Injectable Gene Therapy for Healthy Life Extension
Gene therapy in mice increased lifespan and improved health without causing cancer.
research Group IID, IIE, IIF, and III Secreted Phospholipase A2s
Different sPLA2 enzymes affect immunity, skin and hair health, reproduction, and may be potential targets for therapy.
research COVID-19 and Endocrine and Metabolic Diseases: An Updated Statement from the European Society of Endocrinology
People with diabetes or obesity should manage their conditions carefully as they have a higher risk of severe COVID-19.
research Chemical Characterization and Ameliorating Effect of Centratherum Anthelminticum Extract Against Polycystic Ovary Syndrome in Wistar Rats
Centratherum anthelminticum seed extract effectively treats Polycystic Ovary Syndrome in rats.
research Enzymes
Enzymes play crucial roles in metabolism, health, and disease management.
research Neurosteroidogenesis Today: Novel Targets for Neuroactive Steroid Synthesis and Action and Their Relevance for Translational Research
New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.
research Impact of Nutrition and Exercise on Polycystic Ovarian Syndrome
Eating healthy and exercising can help manage Polycystic Ovarian Syndrome and its related health problems.
research Trends in Nanotechnology for Practical Applications
Nanotechnology is improving drug delivery and targeting, with promising applications in cancer treatment, gene therapy, and cosmetics, but challenges remain in ensuring precise delivery and safety.
research Selection of Antidepressants in Geriatric Dermatoses: A Questionnaire Study of Dermatologists in Western Rajasthan, India
Dermatologists in Western Rajasthan often prescribe doxepin for elderly patients with skin and mental health issues.
research Cardiovascular Disease Risk in Women with Hyperandrogenism, Oligomenorrhea, or Polycystic Ovaries: A Systematic Review and Meta-Analysis
Women with irregular periods have a higher risk of heart disease.
research Neonatal Inhibition of Androgen Activity Alters the Programming of Body Weight and Orexinergic Peptides Differentially in Male and Female Rats
Blocking androgen activity in newborn rats affects body weight and appetite-related hormones differently in males and females.
research Pharmacological BACE1 and BACE2 Inhibition Induces Hair Depigmentation by Inhibiting PMEL17 Processing in Mice
Blocking BACE1 and BACE2 enzymes causes hair color loss in mice.
research Mapping Penetration of Cosmetic Compounds into Hair Fibers Using Time-of-Flight Secondary Ion Mass Spectrometry (TOF-SIMS)
Different oils penetrate hair differently; monounsaturated oils like olive oil penetrate better than polyunsaturated oils.