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Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

Some herbal therapies may help with skin conditions, but more research is needed to confirm their safety and effectiveness.

Some medicinal plants can help heal wounds and may lead to new treatments.

Epidermal stem cells are diverse and vary in activity, playing key roles in skin maintenance and repair.

Low-Level Laser Therapy is effective and safe for hair growth with minimal side effects.

Hair follicle stem cells are key for hair and skin regeneration, can be reprogrammed, and have potential therapeutic uses, but also carry a risk of cancer.

Blocking JAK-STAT signaling can lead to hair growth.

Keratinocytes help heal skin wounds by interacting with immune cells and producing substances that kill pathogens.

Some viruses can cause cancer by changing cell processes and avoiding the immune system; vaccines and targeted treatments help reduce these cancers.

Turmeric may have benefits for skin health, but more research is needed to confirm its effectiveness.

Exosomes could potentially enhance tissue repair and regeneration with lower rejection risk and easier production than live cell therapies.

Different types of stem cells and their environments are key to skin repair and maintenance.

Fat-derived stem cells show promise for skin repair and reducing aging signs but need more research for consistent results.

Inflammation may be linked to hair loss, and targeting specific enzymes could help treat it.

The skin's internal clock affects healing, cancer risk, aging, immunity, and hair growth, and disruptions can harm skin health.

Janus kinase inhibitors are promising treatments for autoimmune skin diseases like eczema and psoriasis.

Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.

The telogen phase of hair growth is active and important for preparing hair follicles for regeneration, not just a resting stage.

Asia has made significant progress in tissue engineering and regenerative medicine, but wider clinical use requires more development.

Modern lifestyles, including poor diet, stress, and long-term use of certain medications, hinder the body's ability to heal from inflammation, leading to chronic diseases.

Smoking harms the skin, causing early aging and increasing cancer risk, but stopping smoking can improve skin health.

Blocking the Wnt pathway could lead to new treatments for cancer and tissue repair but requires careful development to avoid side effects.

Low-level light therapy safely improves hair growth and thickness for androgenetic alopecia.

Formyl-peptide receptor agonists could be new anti-inflammatory drugs.

A specific drug can help treat Lichen Planopilaris, a condition causing permanent hair loss.

Olive oil compounds may help prevent cancer in animals, but human results are mixed.

The document concludes that adult mammalian skin contains multiple stem cell populations with specific markers, important for understanding skin regeneration and related conditions.

Nutraceuticals may improve skin health and protect against aging, but more research is needed on their optimal use and possible health risks.

Cholesterol sulfate buildup due to a genetic mutation disrupts the skin barrier, leading to the scaling skin seen in X-linked ichthyosis.

The Foxn1 gene mutation causes hairlessness and immune system issues, and understanding it could lead to hair growth disorder treatments.