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TRPA1 is crucial for mechanical sensitivity in skin sensory neurons.

The skin's layers protect, sense, and regulate the body's internal balance, but can be prone to cancer.

Some drugs can cause rare but potentially deadly skin reactions, and early treatment and avoiding the drug again are key.

Niosomes are a promising, stable, and cost-effective drug delivery system with potential for improved targeting and safety.

Hair follicles help absorb and store topical compounds, aiding targeted drug delivery.

Hormone therapy for trans individuals is effective and generally safe in the short term.

Dermatologists need to understand hair products to treat hair and scalp issues better.

Essential oils in cosmetics can offer benefits but may cause allergies and should be used carefully.

Fibrinogen/LDL apheresis may improve speech perception in sudden hearing loss, especially for those with high fibrinogen and LDL levels.

COVID-19 can cause different skin symptoms that may help with early diagnosis and show how severe the disease is.

Hormone treatments in transsexual individuals reduce hair growth and oil production in male-to-females and increase them in female-to-males.

Women look young for their age due to larger lips, less sun damage, and genes that prevent gray hair and wrinkles.

Demodicosis is common and often missed, needing more recognition and treatment in skin care.

The document concludes that the exact way alcohol causes harm to fetal development is unknown, but it significantly affects nutrient transport to the fetus and a safe level of alcohol during pregnancy is not determined.

Tributyltin exposure causes sex changes, sterilization, and decline in the snail Ocinebrina aciculata, risking its extinction.

Patients with certain skin symptoms and high ANA titers should be monitored for potential systemic lupus.

Lupus affects the body and skin, causing joint pain and skin issues that can be treated with steroids and antimalarial drugs.

Young adults have about 230,000 tactile nerve fibers, decreasing 5-8% per decade with age.

Pregnancy can cause skin darkening, varicose veins, more sweating, hair growth, hair loss after birth, nail changes, and gum inflammation.

Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.

Protoporphyrin IX is useful in cancer treatment but can cause health problems if not properly regulated.

Early detection and intensive treatment of diseases caused by Staphylococcus aureus toxins are crucial for reducing severe health effects.

Skin problems are very common in people with systemic lupus erythematosus and important for diagnosis.

Choosing the right patients, using proper techniques, and having thorough knowledge are key to preventing and managing dermal filler complications.

The document concludes that understanding hair structure is key to diagnosing hair abnormalities and recommends gentle hair care for management.

Isotretinoin effectively treats severe acne and similar conditions, but has common, mostly reversible side effects, requiring careful patient monitoring.

Testosterone's muscle-building effects do not require its conversion to DHT.

Diffuse alopecia in women may be related to androgens and iron deficiency, and basic hormone and nutrient screening is useful.

Most people on isotretinoin had chapped lips, but only a few stopped the medicine due to side effects.

Asia has made significant progress in tissue engineering and regenerative medicine, but wider clinical use requires more development.