PC038: A Rare Case of Strawberry Gingivitis Associated with Granulomatosis with Polyangiitis (Wegener Granulomatosis)
June 2018
in “
Journal of Clinical Periodontology
”
TLDR A patient with "strawberry gingivitis" improved after correct treatment for Granulomatosis with polyangiitis, highlighting the need for early diagnosis.
The document presents a case report of a 35-year-old female patient with a rare presentation of "strawberry gingivitis," which is associated with Granulomatosis with polyangiitis (GPA), formerly known as Wegener granulomatosis. The patient's gingival hyperplasia developed rapidly over two days and was initially misdiagnosed due to nonspecific histological results and high anti-EBV and CMV antibody titers, leading to a several-week delay in proper treatment. The patient's condition deteriorated, affecting multiple organs and major blood vessels, but improved with aggressive immunosuppressive therapy (corticosteroids and cyclophosphamide) combined with vasodilation therapy. The case emphasizes the importance of early diagnosis in autoimmune vasculitis to control disease progression and administer adequate therapy. The unusual gingival hyperplasia was the initial manifestation of the underlying immune vasculitis, and its early recognition could accelerate proper treatment administration.