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    Did you mean Non-Classical Adrenal Hyperplasia?
    Glossary Non-Classical Adrenal Hyperplasia

    partial enzyme deficiency causing excess androgen production

    Non-Classical Adrenal Hyperplasia (NCAH) is a milder form of congenital adrenal hyperplasia that typically presents later in life, often during adolescence or adulthood. It is caused by a partial deficiency in the enzyme 21-hydroxylase, leading to an overproduction of androgens (male hormones). Symptoms can include irregular menstrual cycles, excessive hair growth (hirsutism), and acne in females, while males may experience early signs of puberty.

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    Research 30 of 738

    1. A Prospective Study of the Prevalence of Nonclassical Congenital Adrenal Hyperplasia among Women Presenting with Hyperandrogenic Symptoms and Signs The Journal of Clinical Endocrinology and Metabolism · 2007 · 150 citations
    2. Phenotypic profiling of parents with cryptic nonclassic congenital adrenal hyperplasia: findings in 145 unrelated families European journal of endocrinology · 2011 · 62 citations
    3. Recommendations for treatment of nonclassic congenital adrenal hyperplasia (NCCAH): An update Steroids · 2011 · 56 citations
    4. Nonclassic Congenital Adrenal Hyperplasia International Journal of Pediatric Endocrinology · 2010 · 49 citations
    5. Nonclassic congenital adrenal hyperplasia Current Opinion in Endocrinology, Diabetes and Obesity · 2012 · 30 citations
    6. The diagnosis of nonclassic congenital adrenal hyperplasia due to 21-hydroxylase deficiency, based on serum basal or post-ACTH stimulation 17-hydroxyprogesterone, can lead to false-positive diagnosis Clinical Endocrinology · 2015 · 25 citations
    7. CYP21A2 Genotypes do not Predict the Severity of Hyperandrogenic Manifestations in the Nonclassical Form of Congenital Adrenal Hyperplasia Hormone and Metabolic Research · 2013 · 14 citations
    8. Sexual Function and Depressive Symptoms in Young Women With Nonclassic Congenital Adrenal Hyperplasia The Journal of Sexual Medicine · 2016 · 11 citations
    9. Nonclassic congenital adrenal hyperplasia and the heterozygote carrier Expert Review of Endocrinology & Metabolism · 2013 · 2 citations
    10. Nonclassical Congenital Adrenal Hyperplasia and Pregnancy Case reports in endocrinology · 2015 · 1 citations
    11. Nonclassic Congenital Adrenal Hyperplasia: An Overview Journal of Pediatric Nursing · 2009
    12. NonClassic Congenital Adrenal Hyperplasia International Journal of Pediatric Endocrinology · 2010 · 59 citations
    13. Management of the Female With Non-classical Congenital Adrenal Hyperplasia (NCCAH): A Patient-Oriented Approach Frontiers in Endocrinology · 2019 · 30 citations
    14. Novel Systematics of Nomenclature and Classification of Female Functional Androgenization (Including Polycystic Ovary Syndrome and Non-Classic Congenital Adrenal Hyperplasia) Journal für Kardiologie (Krause & Pachernegg GmbH) · 2010 · 8 citations
    15. Non-classical congenital adrenal hyperplasia: current insights into clinical implications, diagnosis and treatment Endocrine · 2025 · 5 citations
    16. Roux-en-Y gastric bypass in the treatment of non-classic congenital adrenal hyperplasia due to 11-hydroxylase deficiency BMJ case reports · 2013 · 5 citations
    17. Challenges in treatment of patients with non-classic congenital adrenal hyperplasia Frontiers in Endocrinology · 2022 · 4 citations
    18. Genetic analysis does not confirm non-classical congenital adrenal hyperplasia in more than a third of the women followed with this diagnosis Hormones · 2014 · 1 citations
    19. Severe Hirsutism in Non Classic Congenital Adrenal Hyperplasia: A Case Report and Literature Review Open Access Macedonian Journal of Medical Sciences · 2020
    20. Endocrinology and auxology of sibships with non-classical congenital adrenal hyperplasia. Archives of Disease in Childhood · 1996 · 13 citations
    21. A case of androgen-secreting adrenal carcinoma with non-classical congenital adrenal hyperplasia Indian Journal of Endocrinology and Metabolism · 2013 · 11 citations
    22. Plasma levels of C19 steroid glucuronides in pre-menopausal women with non-classical congenital adrenal hyperplasia 1992 · 7 citations
    23. Urinary 5-ene-steroid excretion in non-classical congenital adrenal hyperplasia due to 3β-hydroxysteroid dehydrogenase deficiency (NC-3BHSD) Journal of Steroid Biochemistry · 1990 · 3 citations
    24. EP1729 - LBA_ECE_1452 - When PCOS is not PCOS: a diagnostic pitfall of non-classical congenital adrenal hyperplasia European Journal of Endocrinology · 2026
    25. Non-classical Congenital Adrenal Hyperplasia Presenting With Severe Androgenic Alopecia: A Case Report Cureus · 2025
    26. Unusual presentation with polymenorrhagia and markedly high 17-hydroxy progesterone levels in a lady with Non-Classic Congenital Adrenal Hyperplasia. PubMed · 2015 · 1 citations
    27. Approaching fertility in congenital adrenal hyperplasia: exploring P30L mutation-induced 21-hydroxylase deficiency with a presentation between non-classical and simple virilizing phenotypes. A case report Medicine and Pharmacy Reports · 2023
    28. Study of Human Leukocyte Antigen ( HLA ) in 13 cases of familial frontal fibrosing alopecia: CYP 21A2 gene p.V281L mutation from congenital adrenal hyperplasia linked to HLA class I haplotype HLA ‐ A*33:01 ; B*14:02; C*08:02 as a genetic marker Australasian Journal of Dermatology · 2019 · 7 citations
    29. 7696 Ovarian Steroid Cell Tumor Presenting As Non-classical Adrenal Hyperplasia Journal of the Endocrine Society · 2024
    30. An Update of Congenital Adrenal Hyperplasia Annals of the New York Academy of Sciences · 2004 · 151 citations