5 citations
,
January 2001 in “Advances in protein chemistry” This chapter reviews recent advances in 5α-reductase inhibitors for treating disorders mediated by dihydrotestosterone and reports no new clinical findings.
3 citations
,
April 2015 in “International research journal of pharmacy” This study concluded that the follicular route is a significant pathway for delivering gentamicin through the skin, as demonstrated by higher drug permeation in non-plugged pig's ear skin compared to plugged skin.
1 citations
,
November 2023 in “Clinical, cosmetic and investigational dermatology” In this review, researchers examined the current status and advancements in using long-pulse alexandrite lasers for treating hair removal, vascular lesions, and pigmented lesions, aiming to guide clinical use based on how the laser's 755nm wavelength is absorbed by melanin and hemoglobin.
August 2023 in “Malaysian Journal of Medicine and Health Sciences/Malaysian journal of medicine and health sciences” This study found that aqueous extract of Pueraria mirifica, when administered to a rat model, significantly reduced prostate weight, prostatic index, and serum dihydrotestosterone levels, while also improving prostate histomorphology, suggesting its potential as an anti-BPH treatment.
January 2022 in “Dermatology Review” This study found that patients with chronic kidney disease-associated pruritus had elevated serum levels of interleukin 31, suggesting a possible role of this cytokine in the condition.
August 2018 in “Journal of The American Academy of Dermatology” Older men's scalp damage increases with age and sun exposure, a baby girl in the Philippines has Schimmelpenning syndrome, and thyroid screening is advised for children with hair loss and certain risk factors.
January 2018 in “Skin appendage disorders” The document focused on hair disorders, especially alopecia, and discussed treatments and impacts on quality of life.
May 2015 in “Journal of The American Academy of Dermatology” A woman with Parry-Romberg syndrome developed new curly hair on one side of her scalp, a condition not previously linked to the syndrome.
178 citations
,
August 2016 in “Advances in wound care” This article discusses advancements in understanding how skin stem cells and fibroblasts contribute to scar formation, highlighting current and potential therapies aimed at preventing or reducing scarring, yet notes that effective treatments without significant side effects are still lacking.
150 citations
,
October 2010 in “The American Journal of Pathology” This review discusses the pathogenesis and challenges in treating primary cicatricial alopecia, highlighting the need to understand immune protection collapse in hair follicle stem cells; it reports no new clinical results.
148 citations
,
February 2005 in “Autoimmunity Reviews” This article discusses the distinct skin findings associated with lupus erythematosus, noting that some are specific to lupus while others are nonspecific and occur with various diseases; it reports no new results.
116 citations
,
December 2017 in “International Journal of Women's Dermatology” This review discusses various treatment options for adult female acne, highlighting the need for tailored approaches due to individual patient needs and reports no clinical outcomes.
99 citations
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December 2010 in “Journal of The European Academy of Dermatology and Venereology” This article discusses the association of acne with various systemic diseases, emphasizing the role of androgen steroids, insulin resistance, and inflammation in acne pathogenesis, but it reports no new clinical results.
38 citations
,
September 2021 in “Signal Transduction and Targeted Therapy” This review discusses genetic factors contributing to susceptibility and outcomes in COVID-19, including ACE, ACE2, TMPRSS2 variants, HLA genotype, and ABO blood group, but reports no new experimental results.
35 citations
,
February 1994 in “Fundamental and applied toxicology” High doses of finasteride cause cell growth and tumors in mice.
23 citations
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February 2004 in “Clinical and Experimental Ophthalmology” This case report describes a 68-year-old woman with metastatic breast cancer who experienced significant improvement in visual acuity after stopping tamoxifen, which was associated with bilateral optic neuropathies.
22 citations
,
June 2007 in “Radiologia Medica” Testicular microlithiasis may increase the risk of testicular cancer and patients with it should be closely monitored.
19 citations
,
January 2021 in “Experimental dermatology” This study found that acne inversa is primarily an epithelial-driven disease, with cyst-forming tendrils causing inflammation due to rupture and the release of debris, highlighting limitations of punch biopsies for analysis.
13 citations
,
January 2024 in “Cureus” This study reviewed the physiological and psychological impacts of acne vulgaris, highlighting its complex interactions with endocrine issues, sebum production, and immune response, while suggesting that a multidisciplinary approach can inform future treatments and improve quality of life for those affected.
13 citations
,
February 2004 in “Clinical and Experimental Ophthalmology” This report describes the clinical and histopathological features of lipoid proteinosis in a brother and sister with lid lesions, highlighting the importance of recognizing such lesions for diagnosis.
11 citations
,
February 2004 in “Clinical and Experimental Ophthalmology” In this case report, the authors suggest an association between prolonged finasteride use and anterior subcapsular cataracts, as observed in a 43-year-old man, marking the first reported instance.
11 citations
,
September 1999 in “Journal of the European Academy of Dermatology and Venereology” This review examines various immunomodulatory therapies for cutaneous lymphoma and notes that they are most effective in the disease's early stages.
11 citations
,
January 1991 in “Urology” This article reviews the potential of combining antiandrogenic and antiestrogenic treatments for BPH, highlighting aromatase inhibitors, but presents no new clinical results; further research is needed.
10 citations
,
November 2019 in “Cold Spring Harbor Perspectives in Biology” This review discusses how recent advances in live imaging have revealed the dynamic and adaptable nature of stem cells during various biological processes, and reports no clinical results.
7 citations
,
February 2004 in “Clinical and Experimental Ophthalmology” This case report details a 65-year-old woman who developed malignant melanoma in her right eye socket following previous eye trauma, treated by orbital exenteration.
7 citations
,
July 1990 in “Journal of the American Academy of Dermatology” This case report describes a patient who developed severe alopecia and a rash after increasing captopril dosage, which resolved upon discontinuing the medication.
6 citations
,
February 2004 in “Clinical and Experimental Ophthalmology” This case report indicates that retinoblastoma can occur in a microphthalmic eye and recommends using multiple imaging techniques due to potential differences in calcification visibility.
research Acne
4 citations
,
January 2019 This analysis examines acne vulgaris using an integrative approach, highlighting its links with psychopathology, lifestyle, and diet, but reports no new results.
4 citations
,
January 1974 in “The BMJ” All medications can cause skin rashes, often without a clear cause, and better tests are needed to identify these drug-related skin issues.
2 citations
,
January 2014 in “Elsevier eBooks” This review discusses drug-induced hypersensitivity syndrome and drug reaction with eosinophilia and systemic symptoms, highlighting clinical features, potential viral reactivations, and treatment, but reports no new clinical findings.