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DHEA may help with sexual function when used intravaginally by menopausal women but is similar to hormone therapy in other aspects and might cause more side effects like acne and hair loss.

Some drugs have gained approval for new uses, while others like tricyclic antidepressants and aspirin show promise but aren't yet approved for these uses.

Hair analysis is better than urine and blood for detecting past drug use.

Jasmonic acid and its derivatives play important roles in plant health and have potential uses in medicine and agriculture.

The study found that urine metabolites M1b or M4 are the best indicators of ATD use in horses, with detection possible up to 77 hours in urine and 28 hours in blood.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

St. John's wort increases finasteride metabolism, reducing its effectiveness; use caution when combining them.

Machine learning can predict symptoms and quality of life in chronic skin disease patients using smartphone app data, and shows that app use varies with patient characteristics.

Smoking increases early hair loss risk in men; quitting may help prevent it.

No single method is best for quitting smoking; it depends on individual preferences and health.

Smoking increases the risk of hair loss, especially male pattern baldness.

Smoking harms skin health, causing slower wound healing, more wrinkles, and worsening some skin conditions, but may protect against certain others.

LCN may improve finasteride delivery for hair loss treatment.

Non-hormonal treatments should be used first for sexual dysfunction in postmenopausal breast cancer patients on aromatase inhibitors, with hormones as a second option.

Tofacitinib, an arthritis drug, helped hair growth in alopecia universalis but long-term safety needs more research.

PSI-MS quickly and accurately measures finasteride in tablets, helping with quality control.

Some natural remedies may help with hair regrowth, but more research is needed to confirm their effectiveness and safety.

Dhatryadi Rasayana, an Ayurvedic herbal mix, may be a safe and effective way to prevent premature hair greying.

Pig skin is a good substitute for human skin to measure drug absorption, but differences in skin structure and enzymes across species must be considered.

Microneedles improve drug delivery in various body parts, are safe and painless, and show promise in cosmetology, vaccination, insulin delivery, and other medical applications.

Vesicular carriers like liposomes may improve cosmetic skin treatment delivery and effectiveness but need more human research.

Systemic retinoids are effective for psoriasis but have side effects; benefits may outweigh risks, especially when reducing cancer risks from other treatments.

Heparin and protamine are promising in tissue repair and organ regeneration, including skin and hair.

Adjuvants, diet changes, and laser therapy may improve male pattern hair loss.

The document suggests that blocking sweat glands with antiperspirants might allow skin-generated hormones to be absorbed, possibly increasing breast and prostate cancer risk.

Caffeine improves hair growth, thickness, and reduces shedding.

More high-quality research is needed to recommend flavonoids and saponins for clinical use.

Finasteride given to baby rats reduces dopamine release and increases alcohol consumption in adult males.

Liposomal systems show promise for delivering drugs through the skin but face challenges like high costs and stability issues.

Chitosan, a natural substance, can be used to create tiny particles that effectively deliver various types of drugs, but more work is needed to improve stability and control of drug release.