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This study observed that microneedling-induced microinjury promotes hair growth via a TNF-α, Wnt, and VEGF pathway, while blocking TNF-α inhibits this process.

This study found that overexpression of betacellulin in transgenic mice delayed hair follicle morphogenesis and cycling, increased keratinocyte proliferation, and enhanced wound angiogenesis without affecting wound healing strength.

Immune cells boost stem cell activity in hairy moles, causing more hair growth.

In this study, researchers found that simple hair clipping in mice induced dynamic plasticity and axogenesis in skin sensory axons, linked to follicular activation and HGF signaling.

This study suggests that hairlessness in nude mice may be due to insufficient expression of phospholipase C-δ1, a molecule essential for normal hair development downstream of the Foxn1 gene.

In this study, transgenic mice with a truncated latent transforming growth factor-beta-binding protein showed reduced keratinocyte proliferation and alterations in the hair cycle due to mis-localization of transforming growth factor-beta.

This study found that overexpressing the BMP inhibitor Noggin in transgenic mice led to a significant loss of nontylotrich hair follicles, suggesting a critical role for BMP signaling in hair follicle morphogenesis and cycling.

This article discusses melanocyte development from neural crest cells and reports no new experimental results; the authors suggest a broader range of functions for melanocytes than previously recognized.

In this study, researchers used NIR-II fluorescence imaging to track the survival and migration of EPI-NCSCs in rat models, finding that these stem cells aided in repairing facial nerve defects when applied via acellular nerve allografts.

This phase I study reported that ETC-159, targeting Wnt signalling, showed tolerable safety profiles at doses that inhibit its pathway, though bone turnover markers increased, warranting early and regular monitoring. No tumor responses were observed, but two patients achieved stable disease for several cycles.

This study demonstrates that neural stem cells in the adult vertebrate brain coordinate their division decisions using delayed local feedback mechanisms, involving Notch-mediated inhibition and dispersion effects, to maintain population homeostasis.

This case report describes a rare co-existence of Becker nevus and plexiform neurofibroma in a child with genetically confirmed neurofibromatosis type 1, offering insights into the potential cellular and molecular links between these lesions.

Zeb2 is crucial for nerve repair by controlling Schwann cell function.

In this study, the researchers reported that altering β-catenin signaling in a transgenic mouse model led to changes in skin cell fate, notably converting hair follicle cells into epidermal cells and forming cysts instead of follicles.

This study found that the transcription factor Trps1 acts as a novel regulator of the Wnt signaling pathway and early hair follicle progenitors in developing vibrissa follicles in mice.

This study found that adiponectin promotes hair growth in cultured human hair follicles, suggesting its receptors could be a target for clinical hair growth strategies.

This article reviews the protective and regenerative mechanisms of nerve fibers and Schwann cells after injury but reports no new findings.

Mutations in the ACTB gene cause Becker’s nevi and may lead to muscle issues in Becker’s nevus syndrome.

In this study, researchers demonstrated that human hair follicle outer root sheath cells release ATP, serotonin, and histamine in response to mechanical stimulation, which subsequently activates surrounding sensory neurons.

This case report found that a 48-year-old woman with idiopathic twenty-nail dystrophy experienced significant improvement in nail appearance after six months of treatment with oral Upadacitinib.

This study identified the Itpr3 gene as responsible for the tufted hair loss phenotype in the BTBR mouse strain.

This study found that GDNF promotes hair formation and skin wound repair by enhancing the self-renewal and differentiation of bulge stem cells in mice.

This study found that the BMP antagonist noggin induces hair growth in postnatal skin by neutralizing BMP4's inhibitory activity, potentially mediated by changes in Shh expression.

This review discusses the role of jumonji family proteins in chromatin regulation and development, highlighting their involvement in transcriptional repression and histone demethylation, but reports no new experimental findings.

This study found that hair follicles in both mice and humans may serve as an important site for melatonin synthesis and signaling, potentially influencing hair cycle regulation by modulating keratinocyte apoptosis.

In this study, researchers observed that nestin-expressing cells in mice can differentiate into blood-vessel-like and nerve-like structures within human melanoma tumors, while bevacizumab treatment altered the origin of these structures to trans-differentiated melanoma cells without significantly impacting tumor growth.

This study identifies Activin A and follistatin as key regulators of hair cell differentiation in the mouse auditory sensory epithelium, influencing the timing and pattern of hair cell development.