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New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.

Potassium channel openers are effective in treating heart conditions, high blood pressure, pulmonary diseases, bladder issues, and hair loss, but more selective drugs are needed.

More men are getting benign prostatic hyperplasia, and there are many treatments, from medication to surgery, with new methods being developed.

Men over 66 taking medication for prostate enlargement have a higher risk of depression and self-harm, especially in the first 18 months of treatment.

The article concludes that better understanding gene regulation related to seasonal changes can offer insights into the mechanisms of seasonal timing in mammals.

The three estrogen receptor genes are highly expressed in zebrafish neuromasts during development.

Finasteride affects brain and blood steroids, causing lasting sexual and emotional side effects.

Post-finasteride patients show changed neuroactive steroid levels, possibly causing erectile dysfunction and depression.

Finasteride may cause suicidal thoughts and mental side effects, especially in young people with hair loss.

Neuroactive steroids show promise for treating mental and neurological disorders by targeting GABA_A receptors.

Finasteride treatment in male rats causes long-lasting effects on depression-like behavior, brain cell growth, inflammation, and gut bacteria composition.

Finasteride reduces new brain cells in male mice, possibly causing depression.

Neuroactive steroids could become safe, effective treatments with more understanding of their complex brain actions and metabolism.

LPA3 is crucial for embryo implantation and links LPA to prostaglandin signaling.

Early onset baldness in men may indicate a condition similar to PCOS, linked to heart disease, diabetes, and prostate issues.

Gene therapy, especially using atoh1, shows promise for creating functional sensory hair cells in the inner ear, but dosing and side effects need to be managed for clinical application.

Trichodynia is a painful scalp condition linked to hair loss and inflammation, often with anxiety, affecting more women and needing better treatment options.

Taking tamsulosin or finasteride and being older increase the risk of floppy iris during cataract surgery.

COVID-19 might worsen symptoms and progression of benign prostatic hyperplasia, possibly due to inflammation and metabolic disturbances in the prostate gland. More research is needed to confirm this.

Some diseases can improve the outcomes of other diseases, leading to new treatment possibilities.

5 alpha-reductase inhibitors can slightly improve symptoms of enlarged prostate but have a high risk of sexual side effects.

Effective treatments for spinal and bulbar muscular atrophy are not yet available; more research is needed.

Metabolic syndrome linked to urinary symptoms; hair loss not significant.

Metformin helps manage diabetes, PCOS, and weight in kids but needs more research for long-term safety.

Finasteride and dutasteride are effective for long-term treatment of enlarged prostates but have sexual side effects and a risk of high-grade prostate cancer.

α-Blockers and 5-ARIs for BPH can cause sexual dysfunction, including erectile and ejaculatory issues.

Exosomes help nerve fibers grow by affecting specific cell signaling pathways.

Blocking 5α-reductase can harm memory and brain structure, and increase harmful brain changes in male mice used for Alzheimer's disease research.

Fluoxetine's effectiveness as an antidepressant in mice depends on a specific protein activity and a 5-minute pretest.

People with early hair loss may have a higher chance of enlarged prostate and metabolic syndrome, so they should be checked for urinary and metabolic issues.