research The Role of AUTS2 in Neurodevelopment and Human Evolution
The AUTS2 gene is linked to neurological disorders and may affect human brain development and cognition.
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research Eph/Ephrin Signaling in Epidermal Differentiation and Disease
Eph/ephrin signaling is important for skin cell behavior and could be targeted to treat skin diseases.
research Dermal EZH2 Simultaneously Orchestrates Dermal Differentiation and Epidermal Proliferation During Murine Skin Development
Dermal EZH2 controls skin cell growth and differentiation in mice.
research Regeneration of Fat Cells from Myofibroblasts During Wound Healing
Some wound-healing cells can turn into fat cells around new hair growth in mice.
research Hormonal Regulation of Hair Follicles Exhibits a Biological Paradox
Androgens can both stimulate and cause hair loss, and understanding their effects is key to treating hair disorders.
research Lineage Commitment of Dermal Fibroblast Progenitors Is Mediated by Chromatin De-repression
Skin cell types develop when specific genes are turned on by removing certain chemical tags from DNA.
research The Biology of Hair Growth
Hair growth is influenced by hormones and goes through different phases; androgens can both promote and inhibit hair growth depending on the body area.
research Dissecting Fibroblast Heterogeneity in Health and Fibrotic Disease
Different types of fibroblasts play various roles in both healthy and diseased tissues, and understanding them better could improve treatments for fibrotic diseases.
research Follistatin Promotes LIN28B-Mediated Supporting Cell Reprogramming and Hair Cell Regeneration in the Murine Cochlea
Follistatin and LIN28B together improve the ability of inner ear cells in mice to regenerate into hearing cells.
research Multi-Scale Spatial Mapping of Cell Populations Across Anatomical Sites in Healthy Human Skin and Basal Cell Carcinoma
The research created a detailed map of skin cells, showing that certain cells in basal cell carcinoma may come from hair follicles and could help the cancer grow.
research Adam10 Haploinsufficiency Causes Freckle-Like Macules in Hairless Mice
A mutation in the Adam10 gene causes freckle-like spots on Hairless mice.
research Dermal β-Catenin Activity in Response to Epidermal Wnt Ligands Is Required for Fibroblast Proliferation and Hair Follicle Initiation
Skin needs dermal β-catenin activity for hair growth and skin cell multiplication.
research Detecting the Mechanism Behind the Transition from Fixed Two-Dimensional Patterned Sika Deer (Cervus Nippon) Dermal Papilla Cells to Three-Dimensional Pattern
The study concluded that changing the culture conditions can cause sika deer skin cells to switch from a flat to a 3D pattern, which is important for creating hair follicles.
research Induction of Dermal Fibroblasts into Dermal Papilla Cell-Like Cells in Hydrogel Microcapsules for Enhanced Hair Follicle Regeneration
Hydrogel microcapsules help create cells that boost hair growth.
research FOXN1: A Master Regulator Gene of Thymic Epithelial Development Program
The FOXN1 gene is crucial for developing immune cells and preventing immune disorders.
research Defining the Identity of Mouse Embryonic Dermal Fibroblasts
Researchers identified specific genes that are important for mouse skin cell development and healing.
research Apoptosis May Explain the Pharmacological Mode of Action and Adverse Effects of Isotretinoin, Including Teratogenicity
Isotretinoin's effects and side effects, like birth defects and depression, might be due to it causing cell death in various cells.
research The Transcriptional Regulator Prdm1 Is Essential for the Early Development of the Sensory Whisker Follicle and Is Linked to the Beta-Catenin First Dermal Signal
Prdm1 is necessary for early whisker development in mice but not for other hair, and its absence changes nerve and brain patterns related to whiskers.
research Thymic Mesenchymal Cells Have a Distinct Transcriptomic Profile
Thymic mesenchymal cells have unique gene expression that supports their specific functions in the thymus.
research Main Plenary Sessions: Summaries of Papers
The document concludes that accurate diagnosis and treatment are crucial in dermatology, and it presents various findings on skin conditions and treatments.
research Anatomy and Function of the Skin
The skin is the largest organ, protecting the body, regulating temperature, and producing hormones.
research Structure and Development of the Skin and Cutaneous Appendages
Understanding skin structure and development helps diagnose and treat skin disorders.
research Dermal Fibroblasts in Cutaneous Development and Healing
Skin cells called dermal fibroblasts are important for skin growth, hair growth, and wound healing.
research Skin Fibroblast Functional Heterogeneity in Health and Disease
Different types of skin fibroblasts have unique roles in skin health and disease.
research A Molecular Wound Response Program Associated With Regeneration Initiation in Planarians
Planarian regeneration begins with a specific gene activation caused by injury, essential for healing and tissue regrowth.
research Site of Beige and Leaden Pigment Gene Expression Determined by Recombinant Embryonic Skin Grafts and Aggregation Mouse Chimaeras Employing Sash Homozygotes
Beige and leaden pigment genes act within melanocytes, affecting pigment patterns.
research A Review of the Etiologies, Clinical Characteristics, and Treatment of Canities
Gray hair is caused by reduced melanin production or transfer issues, linked to aging and possibly health conditions, with treatments focusing on color camouflage.
research Inhibition of β-Catenin Signaling in Dermal Fibroblasts Enhances Hair Follicle Regeneration During Wound Healing
Blocking β-catenin in skin cells improves hair growth during wound healing.
research WNT Signaling in Disease
The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.
research Steroidogenic Factor-1 Lineage Origin of Skin Lesions in Carney Complex Syndrome
Skin lesions in Carney Complex are caused by a gene change in some skin cells that leads to increased pigmentation and may lead to tumors.