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This study utilized a pigmented human epidermal equivalent model to incorporate melanocytes into the epidermis and found enhanced differentiation potential compared to conventional in vitro systems, reflecting in vivo cellular trajectories and highlighting melanocyte-to-keratinocyte communication pathways.

In this study, Trf1 genetic deletion in mice, including those with cancer-prone mutations, was shown to not affect overall viability and cause only mild effects, while being necessary for tumor formation, suggesting a potential therapeutic window for Trf1 as an anti-cancer target.

This study found that dermal fibroblast cultures, especially those with higher alpha-smooth muscle actin expression, can be used to produce skin-derived precursor cells, unlike human hair follicle dermal papilla cultures.

This review summarizes fundamental concepts and recent advancements in hair follicle biology, including insights from mouse models into broader molecular and cellular processes relevant to regeneration and development.

This study demonstrates that bioengineered lacrimal gland germs can successfully develop and restore tear production and ocular surface protection in a mouse model with lacrimal gland dysfunction.

This review discusses the identification and characteristics of melanocyte stem cells, emphasizing their role in hair pigmentation, greying, and skin repigmentation, but reports no new research findings.

This review summarizes recent advancements in follicular targeting for drug delivery via hair follicles and calls for pilot studies in humans to explore potential clinical applications.

This review discusses the various stem cell populations associated with hair follicles and their potential in regenerative medicine, highlighting differences between murine and human hair follicles but reports no new clinical results.

This review discusses the shared molecular and cellular processes in the early development stages of skin appendages like hair follicles, teeth, and mammary glands, reporting no new results.

This review provides a comprehensive guide to serum-free human hair follicle organ culture methods, highlighting research opportunities, standardization efforts, and potential applications without reporting new empirical findings.

This review evaluates existing research on Keratin 15 to assess its validity as a marker for epidermal stem cells, reporting no new results.

This review discusses the use of Dermal Papilla cells as in vitro models for studying hair growth modulators, emphasizing their role in aiding the development of new hair treatments, but reports no new clinical results.

This review discusses the biology of hair follicle stem cells and highlights their potential for applications in regenerative medicine, drug, and gene delivery, but reports no new clinical results.

This review discusses hormonal influences on hair growth and suggests that understanding hormone-gene interactions may improve treatment of hirsutism and alopecia, but reports no new clinical findings.

This review explores the complex relationship between thyroid hormones and skin, discussing potential mechanisms and known interactions but reports no new clinical results, emphasizing the need for further research.

Scarring alopecias are complex hair loss disorders that require early treatment to prevent permanent hair loss.

This mini-review discusses human hair follicle development and summarizes genetic disorders linked to abnormalities in hair follicle morphogenesis, structure, or regeneration, but reports no new experimental results.

This review explores the novel roles of white adipose tissue in tissue homeostasis and regeneration, emphasizing its impact on epithelial, muscle, and immune tissues, and reports no new clinical results.

This study found that hair follicle stem cells could enhance burn wound healing and improve tissue tensile strength in rats.

This study reports that GLP-1 receptors and proglucagon are expressed in the skin of newborn mice, with GLP-1 potentially playing a role in skin development and hair follicle formation.

Bone-marrow and epidermal stem cells help heal wounds differently, with bone-marrow cells aiding in blood vessel formation and epidermal cells in hair growth.

This review explores the potential of using genetically-manipulated stem cells as both therapeutic agents and gene delivery vehicles for enhanced wound regeneration, but it reports no new clinical results.

In this study, epidermal Notch activation increased jagged 1 expression, leading to skin changes like thickening and blistering, with these effects inhibited when jagged 1 was absent.

This study found that measuring reproductive hormone levels in brown bear hair may effectively support non-invasive genetic sampling, though larger samples or more sensitive techniques are needed for broader application.

This study found that the PI3K-Akt signaling pathway is essential for regenerating new hair follicles when epidermal stem cells and skin-derived precursors are combined, suggesting potential therapeutic applications for hair regeneration.

In this study, researchers found that L-cysteine interacted electrostatically with anionic ions on the surface of keratin fibers in human hair, reducing the rate of disulfide bond disconnection at pH 9.0.

This study found that conditional knockout of N-WASP in keratinocytes of mice led to skin barrier defects, increased immune cell infiltration, and hyperproliferation of keratinocytes, indicating its crucial role in skin homeostasis.

This study found that PBX1 enhances the proliferation and reprogramming of hair follicle mesenchymal stem cells by activating the AKT/GSK3β signaling pathway, promoting NANOG expression, and inhibiting apoptosis.

This study found that androgen signaling has complex effects on bone formation in male AR3.6-transgenic mice, with varying impacts based on the embryonic lineage of cells.

In this study, researchers reported that CD34 expression in the isthmic region of canine hair follicles suggests a potential stem cell compartment in this area.