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900-930 / 1000+ resultsresearch Development of a system for clinical evaluation of the biotin status of sows.
In this animal study, serum biotin levels and clinical symptoms in gilts suggested that serum biotin could serve as a sensitive indicator of biotin deficiency, and a system to evaluate biotin status was proposed.
research Reversal of androgenic alopecia by minoxidil: lack of effect of simultaneously administered intermediate doses of cyproterone acetate.
In this case study, a male volunteer with frontal alopecia experienced new hair growth during combined daily treatment with cyproterone acetate and minoxidil, but the new hair was lost after stopping minoxidil.
research [Contribution to hair medulla study (author's transl)].
This study found that medullary cell content in mammal hair evolves from an amorphous form to a biphasic phase, with human and anthropoid hair containing both macrofibrils and microfibrils.
research Diffuse hair loss in women.
This report reviews various presumptive factors contributing to diffuse hair loss in women, emphasizing the need for comprehensive assessment to identify potential underlying causes; it presents no new clinical results.
research [The Netherton syndrome with alopecia and prolinuria].
This case study describes a six-month-old boy diagnosed with Netherton syndrome, featuring ichthyosiform erythroderma and alopecia, possibly linked to aminoaciduria.
research Effect of hair oils and fatty acids on the growth of dermatophytes and their in vitro penetration of human scalp hair.
This study found that mustard oil and unsaturated fatty acids completely suppressed dermatophyte growth and prevented hair penetration at concentrations of 1% and above in Sabouraud's dextrose agar medium.
research The iron content of human hair. II. Individuals with disturbed iron metabolism.
research Enhancing dermal collagen density towards youthfulness: A comparative study of PCL, PLLA, and PDO thread implantation in aging rats model.
This study compared the effectiveness of different thread types in improving collagen profiles in UVB-exposed aging model rats, finding that PCL threads were more effective than PDO and PLLA in enhancing dermal collagen characteristics.
research LncRNA MSTRG.14227.1 regulates the morphogenesis of secondary hair follicles in Inner Mongolia cashmere goats via targeting ADAMTS3 by sponging chi-miR-433
In this study, researchers identified the lncRNA MSTRG.14227.1 in cashmere goats and found it inhibits the morphogenesis of secondary hair follicles by interacting with the chi-miR-433/ADAMTS3 signaling axis, affecting cashmere yield and quality.
research Human Placenta Extract (HPH) Suppresses Inflammatory Responses in TNF-α/IFN-γ-Stimulated HaCaT Cells and a DNCB Atopic Dermatitis (AD)-Like Mouse Model
This study found that human placenta hydrolysate effectively inhibited atopic dermatitis development in stimulated human cells and a mouse model, suggesting its potential as a therapeutic agent for related skin diseases.
research Line‐field confocal optical coherence tomography: Characteristic hints for the diagnosis of scarring alopecia due to lupus erythematodes: A preliminary study
In this study, LC-OCT imaging was found to noninvasively identify specific features of cicatricial alopecia due to lupus erythematosus, such as hyperreflective collagen fibers, which may aid in distinguishing it from other types of scarring alopecia.
research Trichoscopy of Discoid Lupus Erythematosus in Caucasian Scalp: A Review
This study observed that trichoscopy of long-lasting lesions in a chronic stage revealed specific features such as absence of follicular openings, cicatricial patches, and thick arborizing vessels.
research In vitro study of the antioxidant, sun factor protection, antimicrobial, and antifungal activities with molecular docking of methanolic extracts from leaves and fruit of Phillyrea angustifolia L.
research hsa_circ_0002980 prevents proliferation, migration, invasion, and epithelial-mesenchymal transition of liver cancer cells through microRNA-1303/cell adhesion molecule 2 axis
In liver cancer cells, this study found that upregulating hsa_circ_0002980 inhibits cell proliferation, metastasis, and EMT by modulating the miR-1303/CADM2 axis, suggesting it as a potential therapeutic target.
research Relative search popularity of five advanced prostate cancer medications using Google Trends
research Long-term follow-up of a case of feline leishmaniosis treated with a combination of allopurinol and meglumine antimoniate.
This case report describes a rare instance of successful treatment of feline leishmaniosis in a cat, with noted nephrotoxic effects possibly linked to long-term allopurinol use.
research Amelioration of trichotillomania with onabotulinumtoxinA for chronic migraine
This case report describes a woman with trichotillomania who experienced marked improvement and hair regrowth after off-label onabotulinumtoxinA treatment.
research Pseudallescheria boydii infection associated with IgG4-related disease
This report identifies a novel splice-site variant in the LAMB3 gene linked to junctional epidermolysis bullosa, emphasizing the need for gene sequencing in diagnosing the disease.
research Alopecia areata as an immune-related adverse event associated with response to immune checkpoint inhibitors
In this study, researchers using multistate modeling reported that patients with psoriasis treated with brodalumab had a higher probability of achieving and maintaining a therapeutic response compared to those treated with ustekinumab over 52 weeks, based on absolute PASI measurements.
research Hairfluencer social media trends every dermatologist should know in 2021
research Techniques and Applications of Lower Extremity Feminization and Masculinization
This review examines existing plastic surgery techniques for gender affirmation of the lower extremities, noting a lack of outcomes-based literature needed to establish best practices.
research Platelet Rich Plasma for the Treatment of Scarring Alopecia Due to Discoid Lupus Erythematosus.
This review discusses the use of platelet-rich plasma in treating various forms of alopecia, including androgenic alopecia and alopecia areata, but provides no new clinical results.
research The level of stress and the assessment of selected clinical parameters in patients with androgenetic alopecia.
In this study, female patients with androgenetic alopecia reported high stress levels, but the type of hair loss treatment did not significantly affect stress alleviation.
research [Influence of the stiffness of three-dimensionally bioprinted extracellular matrix analogue on the differentiation of bone mesenchymal stem cells into skin appendage cells].
This study observed that bone marrow mesenchymal stem cells cultured in three-dimensionally bioprinted hydrogels with higher stiffness, like 3A8G, tend to differentiate more into hair follicle cells compared to those in less stiff hydrogels, like 1A4G.
research Alopecia Areata: A Complex Cytokine Driven Disease
This research discusses the complex immune pathogenesis of alopecia areata and highlights the success of Jak inhibitors and IL-4Rα antagonists, while IL-17A and PDE4 inhibitors showed limited efficacy; controlled trials are advocated to better understand cytokine involvement.
research Progress in the Use of Platelet-rich Plasma in Aesthetic and Medical Dermatology.
This review discusses the potential efficacy and applications of platelet-rich plasma in dermatology, highlighting its use in various skin conditions but reporting no new clinical results; the authors call for standardization of preparation and treatment methods.
research The Use of Natural Ingredients in the Treatment of Alopecias with an Emphasis on Central Centrifugal Cicatricial Alopecia: A Systematic Review.
This review discusses the absence of clinical trials on natural ingredients for managing Central Centrifugal Cicatricial Alopecia and highlights a need for more research.
research [Differences in efficacy between drug-eluting beads transbronchial arterial chemoembolization combined with systemic chemotherapy and systemic chemotherapy alone for unresectable lung squamous cell carcinoma].
This study found that DEB-BACE combined with systemic chemotherapy was more effective than chemotherapy alone for unresectable lung squamous cell carcinoma, reducing side effects and improving survival rates.
research IGF1- and BM-MSC-incorporating collagen-chitosan scaffolds promote wound healing and hair follicle regeneration.
This study found that using insulin-like growth factor 1 with bone marrow-derived mesenchymal stem cells in a collagen-chitosan scaffold enhanced wound healing and hair follicle regeneration in rats.