Contribution to Hair Medulla Study

    January 1981 in “ PubMed ”
    Clément Jl, Le Pareux A, Ceccaldi Pf
    TLDR Hair medullary cells in mammals vary in complexity, with humans having more structured cells similar to inner root sheath cells.
    The study by J L Clément et al. focused on the anatomical characteristics of hair medullary cells across different mammalian genera. It was found that the medulla and inner root sheath are sulfur-poor but rich in citrulline, with proteins bound by epsilon(gammaglutamyl)lysine dipeptides. Observations using SEM and TEM revealed that medullary cells are complex and evolve differently among mammals. In superior mammals, medullary cells transition to a biphasic or granular phase, while in humans and closely related anthropoids, they contain macrofibrils and microfibrils. These microfibrils are similar to those in the inner root sheath, explaining the presence of citrulline and epsilon(gammaglutamyl)lysine bonds in medullary cells.
    Discuss this study in the Community →

    Related Community Posts Join

    6 / 1000+ results

      community Hair Loss “Cure” for Inflammation: Topical Roflumilast

      in Research/Science  31 upvotes 3 days ago
      Topical roflumilast is effective for reducing inflammation in various scalp conditions like seborrheic dermatitis, psoriasis, and eczema, but not proven to stop scarring alopecia. Alternatives like apremilast and Vtama are also discussed for their anti-inflammatory benefits.

      community Hair loss stack thoughts? New to this!

      in Treatment  2 upvotes 5 days ago
      The conversation is about a hair loss treatment plan involving finasteride, minoxidil, microneedling, GHK-CU injections, Nizoral shampoo, and RU58841. The user is advised to start with a simpler regimen to minimize side effects and assess effectiveness before adding more treatments.

      community Hair loss over a year following depression and taking antidepressants

      in Side effects?  196 upvotes 1 week ago
      A 33-year-old experienced significant hair loss after a depressive episode and taking paroxetine, possibly due to telogen effluvium or androgenic alopecia. Suggestions included reducing alcohol, considering finasteride and minoxidil, and consulting a doctor about antidepressant side effects.

      community Hair loss journey - progress check & questions

      in Progress Pictures  1 upvotes 1 week ago
      The user shared their hair loss journey, using Minoxidil 2%, Serenoa repens, topical finasteride, a topical antiandrogen, Vitamin D, and lifestyle changes, noting improvements but still seeking more density. They are considering switching to Minoxidil 5% but prefer focusing on finasteride and antiandrogen for better results.

    Related Research

    1 / 1 results