Contribution to Hair Medulla Study

This study investigated the anatomical characteristics of hair medullary cells across different mammalian genera. It was found that the medullary cells, which are sulfur-poor but rich in citrulline and proteins bound by epsilon(gammaglutamyl)lysine dipeptides, evolved in complexity similar to other hair cells. Observations using SEM and TEM revealed that while some mammals have amorphous medullary cell content, superior mammals exhibit a biphasic or granular phase. In humans and closely related anthropoids, medullary cells contain macrofibrils and microfibrils, akin to those in the inner root sheath, explaining the presence of citrulline and specific peptide bonds in these cells.