Influence of the Stiffness of Three-Dimensionally Bioprinted Extracellular Matrix Analogue on the Differentiation of Bone Mesenchymal Stem Cells into Skin Appendage Cells

November 2020 in “ PubMed ”

Enhejirigala, Y J Zhang, J J Li, Bin Yao, Wei Song, Sha Huang, Xiaobing Fu

extracellular matrix bone marrow mesenchymal stem cells BMSCs hair follicle cells skin appendage cells sweat gland cells hydrogels 3A8G hydrogel 1A4G hydrogel

Studysummary This study observed that bone marrow mesenchymal stem cells cultured in three-dimensionally bioprinted hydrogels with higher stiffness, like 3A8G, tend to differentiate more into hair follicle cells compared to those in less stiff hydrogels, like 1A4G.

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