815 citations
,
April 2010 in “The Journal of Clinical Endocrinology & Metabolism” This review examines the relationship between polycystic ovary syndrome and cardiovascular disease risk, but reports no new clinical findings; the panel calls for guidelines to prevent CVD in this population.
122 citations
,
November 1998 in “Archives of Dermatology” This study found that aromatherapy involving essential oils significantly improved symptoms of alopecia areata compared to carrier oils alone in a randomized controlled trial.
29 citations
,
February 2007 in “Hormone and metabolic research” This study found that antisense oligonucleotides can significantly reduce androgen receptor expression in cultured human sebocytes and may offer new therapeutic possibilities for androgen-associated skin diseases.
22 citations
,
April 2020 in “Scientific reports” This study explored gene expression in Changthangi goats and found that higher expression of keratin-related genes and specific signaling pathways may play a role in the development of Pashmina fiber.
19 citations
,
December 2015 in “Journal of Materials Chemistry B” This study found that using layer-by-layer encapsulation techniques on dermal papilla cells can support their function and may help treat hair loss when used in conjunction with freshly isolated epidermal cells.
19 citations
,
June 2007 in “Veterinary Dermatology” In this study, amitraz was found to be an effective and well-tolerated treatment for resolving sarcoptic mange in alpacas, demonstrating no relapse over a 10-month follow-up.
18 citations
,
October 2018 in “Nutrients” This study found that Annurca apple polyphenolic extracts reprogram hair follicle metabolism in mice, enhancing mitochondrial activity and keratin production while inhibiting some metabolic pathways.
12 citations
,
August 2017 in “Pharmaceutical medicine” This study found that physician knowledge of thromboembolism risk associated with cyproterone acetate/ethinylestradiol was generally high, although it varied for complex or less common topics.
10 citations
,
March 2014 in “Scandinavian journal of clinical and laboratory investigation” This study found that MDA-modified DNA may contribute to immune responses in alopecia areata patients by creating neo-epitopes, providing new insights into the condition's immunological mechanisms.
2 citations
,
January 2015 in “Elsevier eBooks” The document says biodegradable cosmetics and packaging are better for the environment and user experience.
1 citations
,
October 2023 in “PloS one” This study found that testosterone concentrations in hair samples were moderately stable over three months, with cosmetic treatments like coloring increasing testosterone levels, while natural hair color in untreated hair did not affect testosterone measurements.
June 2026 in “Frontiers in Materials” This review examines advancements in "smart" hydrogel dressings for complex wound healing, highlighting innovations in materials that provide multifunctionality, such as responsive drug delivery and regenerative capabilities. The study also addresses potential challenges in clinical application, like manufacturing and regulatory hurdles.
December 2025 in “Applied and Computational Engineering” In this study, researchers explored the potential allergenicity and harmful effects of hair dyes, noting that adverse effects such as sensitization and potential carcinogenicity are not inevitable and can vary based on individual physiological differences.
September 2025 in “Journal of Health Sciences” In this study, researchers developed an antioxidant hair tonic using Dipteryx odorata (cumaru) extract, aimed at treating scalp psoriasis, which could potentially improve quality of life for patients due to its natural anti-inflammatory and antioxidant properties.
August 2025 in “Advances in Therapy” In this study, the researchers noted that physicians in China prioritize clinical hyperandrogenism when making PCOS treatment decisions, highlighting a need to align clinical practices with guidance recommendations and to clarify the role of biochemical hyperandrogenism in future guidelines.
In this systematic review, the authors reported that both FUE and FUT hair transplant techniques induce oxidative stress and inflammation, impacting graft survival, but interventions like PRGF, CO2 laser, and dermal microtissues can enhance healing, reduce inflammation, and improve follicular survival.
January 2023 in “Journal of pharmacognosy and phytochemistry” This discussion concluded that many herbal home remedies are effective for treating alopecia and other hair conditions without causing adverse reactions, as opposed to allopathic medicines that often have undesirable side effects.
212 citations
,
September 2015 in “Journal of Investigative Dermatology” This article presents a comprehensive guide for classifying human hair follicle cycle stages in vivo using scalp xenografts on immunocompromised mice, offering valuable resources for researchers in the field.
17 citations
,
September 2020 in “Journal of Endocrinological Investigation” This study found that the gut microbiota composition in patients with post-finasteride syndrome differs significantly from healthy controls, with reduced diversity and specific microbial changes, suggesting a potential diagnostic marker and therapeutic target.
4 citations
,
January 2019 in “Elsevier eBooks” This review examines the current landscape of drug repositioning, highlighting that computational methods expand possibilities for reusing existing drugs to treat unmet medical needs. The authors discuss both the potential of these methods and the challenges faced in identifying new therapeutic applications.
1 citations
,
October 2023 In this study, the authors found that syntax-based neural networks performed comparably to pre-trained Transformers on tasks involving definitely unseen sentences, suggesting they are a more transparent and parameter-efficient alternative for certain Natural Language Processing applications.
December 2025 in “Scientific Reports” In this study, researchers observed that DHEA-induced PCOS rats experienced significant changes in gut microbiota and metabolic profiles, particularly affecting steroid and lipid metabolism, suggesting the gut-ovary axis may play a role in the pathogenesis of PCOS.
This study suggests that pre-trained Transformers only outperform syntactic and lexical neural networks on unseen DarkNet sentences after extreme domain adaptation, indicating unexpected advantages from their massive pre-training corpora.
330 citations
,
December 2009 in “Cell stem cell” This study suggests that skin-derived precursors from Sox2(+) hair follicle dermal cells have the potential to function as dermal stem cells, supporting hair morphogenesis, dermal maintenance, and wound-healing.
115 citations
,
March 2019 in “Nature Communications” This study identified significant genetic associations with frontal fibrosing alopecia at four genomic loci, suggesting it is a genetically predisposed immuno-inflammatory disorder influenced by the HLA-B*07: 02 allele.
1 citations
,
November 2017 in “Expert opinion on orphan drugs” This review discusses the genetic basis of ectodermal dysplasia, highlighting that identification of gene pathologies enhances diagnosis and supports prenatal DNA testing, but it reports no new clinical results.
522 citations
,
January 2001 in “Cancer investigation” This review describes the unique pharmacological profile and clinical applications of pegylated liposomal doxorubicin, emphasizing its role in Kaposi's sarcoma and recurrent ovarian cancer, but reports no new clinical results.
253 citations
,
April 2014 in “Drugs” This review discusses the preclinical and clinical data on teriflunomide for multiple sclerosis, highlighting its selective action on immune cells without causing clinical immune suppression, and provides no new clinical results.
234 citations
,
April 2000 in “Gene” This review discusses the expression patterns and biochemical roles of Msx and Dlx genes during development but does not present new research findings.
204 citations
,
May 2014 in “The Journal of Sexual Medicine” This study concluded that current cross-sex hormone treatments for trans men and trans women are effective with a low risk of side effects in the short term, though they did observe specific clinical changes.