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The protein p53 directly reduces the production of Keratin 17, a skin and hair protein, in rats with radiation dermatitis.

Anti-cancer treatments can cause reversible hair loss, skin sensitivity, pigmentation changes, nail damage, and skin reactions, with a need for more research on managing these side effects.

Hair keratins evolved from ancient proteins, diversifying through gene changes, crucial for forming claws and later hair in mammals.

Patients with chronic renal failure on hemodialysis often have skin problems like dry skin, itching, and nail changes.

Hair and wool have diverse keratins and keratin-associated proteins.

RSPO1 mutations in certain patients lead to skin cells that don't develop properly and are more likely to become invasive, increasing the risk of skin cancer.

Elkonyxis, a rare nail condition, improved when patients stopped their nail-picking habits.

Keratin protein production in cells is controlled by a complex system that changes with cell type, health, and conditions like injury or cancer.

The document says that there are treatments for hair and nail diseases.

Understanding keratinization is crucial for treating skin conditions like ichthyoses and psoriasis.

Early diagnosis and treatment of nail and skin conditions can improve health and appearance.

The document concludes that skin and nail changes can indicate various underlying health conditions.

Human hair keratin might be good for filtering out harmful substances from water.

Uncombable hair syndrome causes frizzy hair and can affect the nervous system, eyes, and ears, often co-occurring with other hair, skin, nail, and teeth conditions, and is linked to three specific gene mutations.

Diabetic patients often have ingrown nails due to obesity, high blood pressure, past injuries, bad nail trimming, nail fungus, weak foot pulse, and weak knee reflex.

Darier-White disease causes skin and nail issues, starts around age 20, worsens until 40-50, and has poor treatment options.

No link between scalp patterns and alopecia severity in children, but more severe cases often had nail abnormalities.

Online medical education helps doctors make better clinical decisions and increases their knowledge in treating fungal nail infections.

Low-dose acitretin helps nail psoriasis, stem cells may treat scarring alopecia, Chinese men have lower baldness rates, lateral foldplasty is good for ingrown toenails, hair diameter helps diagnose female baldness, childhood trauma linked to alopecia areata, certain hair-weaving leads to scalp conditions in African American women, and new methods for hair research and understanding hair and sweat gland development were introduced.

Keratin proteins are increasingly recognized as important for cell health and are linked to many diseases.

Progerin affects cell shape but not hair or skin in mice.

Keratin proteins are essential for keeping the cells in the human colon healthy and stable.

Mutations in specific keratin genes cause improper hair structure in mice due to faulty keratin protein assembly.

Keratin from hair binds well to gold and BMP-2, useful for bone repair.

The KRTAP11-1 gene promoter is crucial for specific expression in sheep wool cortex.

pCLCA2 protein may help maintain skin structure and function.

The C-terminal tail of AHF/trichohyalin is essential for organizing keratin filaments in keratinocytes.

Genes related to keratin, skin cell differentiation, and immune functions are key in hedgehog skin and spine development.

YH0618 helps reduce chemotherapy-induced hair loss by targeting specific proteins and pathways.