Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This study explored a new dutasteride nanocarrier for alopecia therapy, concluding that ingredient concentration is key to achieving the optimal particle size, stability, and skin permeation for extended drug release.

This study optimized efinaconazole spanlastic nanovesicles using risk management and multivariate analysis for potential transungual delivery to treat onychomycosis, achieving improved drug permeability and dissolution efficiency.

In testosterone-induced AGA mouse models, this study found that a dual-drug-loaded cationic nanoemulsion of minoxidil and finasteride enhanced follicle-associated retention, supporting hair regeneration while reducing systemic absorption and showing good skin compatibility, indicating a promising approach for androgenetic alopecia treatment.

In this study, researchers developed and optimized ethanol-free microemulsion systems for transdermal finasteride delivery, finding that the predicted formulations closely matched their physical and chemical characteristics, potentially reducing adverse effects compared to oral administration.

This study demonstrated that liquid-state vesicles may reduce the absorption of finasteride through the skin while increasing its concentration and retention in the dermis layer in hamster models.

In this study, a new herbal hair oil formulation, consisting of plant-derived antifungal agents and natural stabilizers, was developed and demonstrated strong antifungal activity, skin compatibility, and additional hair health benefits in preclinical evaluations, offering a potential alternative for managing fungal scalp infections.

This in-silico study found that Finasteride interferes with neurotransmitters and may increase psychopathology when it decomposes into a carboxylic acid similar to Cortisol.

Terbinafine is more effective than itraconazole for toenail fungus, especially in older patients, and debridement improves its effectiveness.

This study aimed to enhance the skin penetration of brown algae fucoidan using a Nanostructured Lipid Carrier, achieving a formulation with good physical quality and stability.

This study suggests that weekly oral finasteride may be a promising alternative to isotretinoin for treating nodulocystic acne, showing substantial improvements with lower incidence of sexual dysfunction.

This article describes a new synthesis method for finasteride that reduces the use of costly and toxic reagents, making it more suitable for large-scale production, but reports no clinical results.

This study found that the optimized nanostructured lipid carrier formulation effectively enabled caffeine to penetrate and accumulate in hair follicles, suggesting potential for intrafollicular delivery in treatments for hair loss.

This study reports a new industrial process for making finasteride using novel protective groups, demonstrated through spectral data of newly prepared compounds.

NB-002 is a promising new topical treatment for fungal nail infections, showing better results than a non-medicated option.

This study found that preparing finasteride as a nanosuspension increased its aqueous solubility by more than 2.5 times, potentially enhancing drug bioavailability.

The flutamide-loaded hydrogel is a promising, skin-friendly treatment for acne and hair loss, potentially requiring less frequent application.

This study found that terbinafine HCl nail solutions with or without DDAIP HCl significantly outperformed ciclopirox nail lacquer in treating guinea pig dermatophytosis, suggesting potential effectiveness for human nail infections.

Nanostructured lipid carriers can improve alopecia treatment by enhancing drug delivery and promoting hair growth.

This study reviewed early research on topical finasteride for androgenetic alopecia, finding it appears safe and promising, though further investigation is needed to determine optimal dosing, frequency, and potential applications for other types of alopecia.

This study successfully developed a synthetic route for finasteride that achieves a 30.6% yield and is suitable for industrial production, avoiding the use of expensive or poisonous reagents.

This study concluded that niosomes could effectively serve as stable carriers for topical aminexil delivery, showing promising stability and a slow, biphasic release profile in laboratory settings.

The two lotions used day and night may be a good alternative to minoxidil for hair loss treatment with better cosmetic effects and tolerance.

In this study, researchers reported that topical nanostructured lipid carriers containing tea seed or lavender oil significantly enhanced hair regrowth in female Wistar albino rats over 30 days compared to placebo, with increased hair length and follicular density observed.

This study observed that nicotinamide can effectively inhibit human hair growth and promote hair follicle regression in cultured human scalp models without negatively affecting epidermal vitality, suggesting its potential as a hair growth inhibitor in cosmetic applications.

This study found that injecting nanofat into the scalp significantly improved hair density and led to high patient satisfaction among 20 individuals with androgenic alopecia, with minimal side effects, although further research is necessary to refine the technique and confirm these results.