research Using the Frog Embryonic Epidermis as a Model to Study Desmosome Function During Development
Frog skin cells need the protein desmoplakin for proper development and cell layer formation.
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research Comparative Analysis of Treatment Methods for Androgenetic Alopecia Using a Combination of Zinc Hyaluronate Gel and Physical Factors
Combining zinc hyaluronate electroporation with photostimulating therapy is more effective for treating hair loss in men and women.
research Faculty Opinions Recommendation of Thymic Peptides Differentially Modulate Human Hair Follicle Growth
Thymic peptides can either promote or inhibit human hair growth.
research Patent Evaluation: Δ-4,6-Steroids as Potent 5α-Reductase Inhibitors
New steroids were patented as effective for treating acne, hair loss, and other conditions related to hormones.
research Expression Patterns of MITF During Human Cutaneous Embryogenesis: Evidence for Bulge Epithelial Expression and Persistence of Dermal Melanoblasts
Melanocyte precursors in human fetal skin follow a specific migration pattern and some remain in the skin's deeper layers.
research Efficacy of Metformin Therapy in Adolescent Girls with Androgen Excess: Relation to Sex Hormone-Binding Globulin and Androgen Receptor Polymorphisms
Metformin works better for adolescent girls with PCOS who have certain genetic variations.
research New Approach to 3-Oxo-4-Aza-5α-Androst-1-Ene-17β-(N-Tert-Butylcarboxamide)
A new method was developed to make finasteride for treating hair loss.
research Minoxidil Topical Treatment May Be More Efficient If Applied on Damp Scalp Compared to Dry Scalp
Minoxidil works better when applied on a damp scalp than a dry one.
research Effect of Melatonin Supplementation from Mid to Late Gestation on Hair Growth and Skin Temperature of Beef Cattle
Melatonin supplementation may lower skin temperature in unshaved areas of pregnant beef cattle.
research Consumption of a Low-Carbohydrate and High-Fat Diet Exaggerates Biotin Deficiency in Mice
The ketogenic diet can worsen biotin deficiency, suggesting a need for biotin supplements.
research Inhibition of 5α-Reductase Alters Pregnane Metabolism in the Late Pregnant Mare
Inhibiting 5α-reductase increases progesterone levels in late pregnant mares.
research Preparation and Evaluation of Hair Growth Formulations of Indian Ginseng (Withania Somnifera) for Alopecia
Indian Ginseng may help promote hair growth for treating alopecia.
research Psycho-Emotional Conditions in Patients with Non-Scarring Alopecia (Circumscribed, Androgenetic)
Patients with non-scarring hair loss often have emotional disorders.
research A Biochemical Marker In A Dominant Mouse Trait
The study investigated the biochemical differences in hair between mice heterozygous for the Naked (N) trait and normal mice. It found that the mutant hair had significantly lower levels of glycine and tyrosine, with 20% less glycine and 27% less tyrosine compared to normal hair. Further analysis showed that proteins extracted from Nn hair contained 30% less glycine and 40% less tyrosine. These findings indicated that the Nn hair was deficient in a specific protein fraction rich in glycine and tyrosine, which comprised about 25% of the total protein in mouse hair. This mutation served as a biochemical marker for a dominantly inherited trait.
research Hair Growth-Promoting Activity of Hot Water Extract of Thuja Orientalis
Thuja orientalis hot water extract may help hair grow by starting the growth phase and improving hair follicle development.
research The Role of Patients in Alopecia Areata Endpoint Development: Understanding Physical Signs and Symptoms
The main goal for new Alopecia Areata treatments should be significant improvement in scalp hair growth.
research Psycho-Emotional Conditions of Patients with Non-Scarring Alopecia (Circumscribed, Androgenetic)
Patients with non-scarring alopecia often experience emotional disorders like depression and stress.
research Irregular Menstruation, Acne, Hirsutism, and the Possibility of PCOS
Women with irregular periods should be checked for PCOS and treated early to prevent complications, with birth control pills helping to manage symptoms.
research Relationships Between Cerebrospinal Fluid GABAergic Neurosteroid Levels and Symptom Severity in Men with PTSD
Lower levels of certain brain chemicals are linked to worse PTSD symptoms in men.
research Effect of Constant-Release Melatonin Implants and Prolonged Exposure to a Long Day Photoperiod on Prolactin Secretion and Hair Growth in Mouflon (Ovis Gmelini Musimon)
Melatonin implants and long daylight hours alter the timing of hormone release and hair growth in mouflon sheep.
research Template-Directed Self-Assembly and Growth of Insulin Amyloid Fibrils
A new method speeds up insulin amyloid fibril growth, useful for studying diseases.
research Incomplete Recovery of Erectile Function in Rats After Discontinuation of Dual 5-Alpha Reductase Inhibitor Therapy
Rats had lasting erectile problems after stopping a certain medication.
research Transforming Growth Factor-β, Smad, and Collagen Expression Patterns in Fetal and Adult Keratinocytes
Keratinocytes show more TGF-β system activity and collagen production as they age, which might affect wound scarring.
research 3,3-Diphenylpentane Skeleton as a Steroid Skeleton Substitute: Novel Inhibitors of Human 5α-Reductase 1
A new compound effectively inhibits human 5α-reductase 1.
research Self-Consistent Field Theory for the Interactions Between Keratin Intermediate Filaments
Keratin filaments' elasticity is influenced by their terminal domains and surrounding medium.
research Process Development and Crystallization in Oiling-Out System of a Novel Topical Antiandrogen
In 2017, a new method was created to efficiently produce a topical antiandrogen, a compound used to treat excess sebum and acne, with a high yield and purity.
research Finasteride in Hospitalized Adult Males with COVID-19: A Risk Factor for Severity or an Adjunct Treatment - A Randomized Controlled Clinical Trial
Taking finasteride can partially improve oxygen levels in hospitalized male patients over 50 with COVID-19 pneumonia, but it doesn't affect other outcomes like death rate or hospital stay length.
research Suppression of Cutibacterium Acnes-Mediated Inflammatory Reactions by Fibroblast Growth Factor 21 in Skin
FGF21 can help reduce skin inflammation caused by C. acnes.
research Involvement of Neurosteroids in the Control of Hypothalamic-Pituitary-Adrenal Axis Activity in Pregnant Sheep Under Basal and Stressful Conditions
Neurosteroids play a key role in controlling the brain-adrenal gland activity in pregnant sheep, both in normal and stressful situations.
research Serum C-19 Steroid Sulphates in Females with Clinical Hyperandrogenism
Women with hyperandrogenism have higher androgen levels and lower SHBG, which may contribute to conditions like excessive hair growth and early puberty.