research Synthesis and Actions of 5α-Reduced Metabolites of Testosterone in the Nervous System
Testosterone and its metabolites affect brain functions and could help treat neurological disorders.
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research De Novo Single-Nucleotide and Copy Number Variation in Discordant Monozygotic Twins Reveals Disease-Related Genes
The research found genetic differences in identical twins that could explain why one twin has a disease while the other does not.
research Hair Analysis in Health Assessment
Hair mineral analysis might help diagnose diseases early, but standard methods are needed.
research Association of Lifelong Intake of Barley Diet with Healthy Aging: Changes in Physical and Cognitive Functions and Intestinal Microbiome in Senescence-Accelerated Mouse-Prone 8 (SAMP8)
Eating barley for life may lead to healthier aging in mice.
research How Biodegradable Polymers Can Be Effective Drug Delivery Systems for Cannabinoids: Perspectives and Challenges
Biodegradable polymers can improve cannabinoid delivery but need more clinical trials.
research From Gene to Therapy in Spinal and Bulbar Muscular Atrophy: Are We There Yet?
Effective treatments for spinal and bulbar muscular atrophy are not yet available; more research is needed.
research Hunting the Genes in Male-Pattern Alopecia: How Important Are They, How Close Are We and What Will They Tell Us?
Genes play a significant role in male-pattern baldness, and understanding them could lead to new treatments and insights into related health issues.
research Aging Skin: A Window to the Body
Skin aging reflects overall body aging and can indicate internal health conditions.
research Association Between Genetically Predicted Leukocyte Telomere Length and Non-Scarring Alopecia: A Two-Sample Mendelian Randomization Study
Shorter telomeres in white blood cells may increase the risk of a common type of hair loss.
research Role of Drug Repurposing in Sustainable Drug Discovery
Drug repurposing speeds up drug development, saves money, and has led to about a third of new drug approvals.
research Potential Therapeutic Applications of Bee Venom on Skin Disease and Its Mechanisms: A Literature Review
Bee venom might be a good alternative treatment for various skin conditions because it has many healing properties.
research Culture of Pyramidal Neural Precursors, Neural Stem Cells, and Fibroblasts on Various Biomaterials
Different materials affect the growth of brain cells and fibroblasts, with matrigel being best for brain cell growth.
research NF-κB in Biology and Targeted Therapy: New Insights and Translational Implications
NF-κB signaling is crucial in many diseases and can be targeted for new treatments.
research Low-Level Laser and Light Therapy
Low-Level Laser Therapy can stimulate healing and cell function, potentially leading to wider medical use.
research Toxicology and Pharmacology of Botulinum and Tetanus Neurotoxins: An Update
Botulinum and tetanus neurotoxins are better understood now, with updated information on their effects and treatment.
research Therapeutic Effects of Stem Cells in Different Body Systems: A Comprehensive Review
Stem cell therapy is promising for treating various health conditions, but more research is needed to understand its full potential and address challenges.
research Questionnaire Modifications and Alternative Scoring Methods of the Dermatology Life Quality Index: A Systematic Review
There is a significant need for better-validated quality of life tools in dermatology.
research Clinical and Genetic Aspects of Alopecia Areata: A Cutting Edge Review
Hair loss from Alopecia Areata is caused by both genes and environment, with several treatments available but challenges in cost and relapse remain.
research Mechanism of Action of Bolandiol (19-Nortestosterone-3β,17β-Diol), a Unique Anabolic Steroid with Androgenic, Estrogenic, and Progestational Activities
Bolandiol, a synthetic steroid, builds muscle and bone without greatly affecting sex glands, and works differently from other hormones.
research The Mechanisms of Anabolic Steroids, Selective Androgen Receptor Modulators, and Myostatin Inhibitors
Anabolic steroids boost muscle growth, SARMs increase muscle mass and bone density without side effects, and myostatin inhibitors block a protein that stops muscle growth, but each has potential risks.
research Adverse Health Effects of Androgen Use
Using anabolic androgenic steroids can cause serious, lasting health problems in many parts of the body.
research Aesthetic Rehabilitation Medicine: Enhancing Wellbeing Beyond Functional Recovery
Aesthetic rehabilitation techniques can improve life quality and wellbeing for disabled patients.
research Industry Update: The Latest Developments in the Field of Therapeutic Delivery, July 2018
New partnerships, clinical trials, and drug approvals marked progress in therapeutic delivery in July 2018.
research Eph Receptors and Ephrins: Therapeutic Opportunities
Eph receptors and ephrins may be promising targets for treating diseases, but more understanding is needed for effective and safe therapies.
research Perspectives of Kennedy's Disease
Kennedy's disease leads to muscle weakness and sensory issues, has no cure but manageable symptoms, and future treatments look promising.
research Exploring the Drug Repurposing Versatility of Valproic Acid as a Multifunctional Regulator of Innate and Adaptive Immune Cells
Valproic Acid could potentially be used to treat immune-related conditions due to its ability to modify immune cell functions.
research Men With Kennedy Disease Have a Reduced Risk of Androgenetic Alopecia
Men with Kennedy disease have less chance of hair loss.
research Altered Resting-State Activity in Seasonal Affective Disorder
People with Seasonal Affective Disorder have different brain activity in certain areas when resting.
research TSPO Activation Modulates the Effects of High Pressure in a Rat Ex Vivo Glaucoma Model
Activating TSPO helps protect the retina from damage caused by high eye pressure in glaucoma.
research TLR2 Regulates Hair Follicle Cycle and Regeneration via BMP Signaling
TLR2 is important for hair growth and can be targeted to treat hair loss.