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The document concludes that understanding sulfation biology is crucial for creating treatments due to its importance in biological functions and disease.

Four-amino acid part makes enzyme sensitive to finasteride.

The TGF-β family helps control how cells change and move, affecting skin, hair, and organ development.

Skin has specialized touch receptors that can tell different sensations apart.

Hair shedding is an active process that could be targeted to treat hair loss.

Certain mutations in the H6PD gene cause Cortisone Reductase Deficiency by affecting hormone production.

Follistatin helps hair growth and cycling, while activin prevents it.

White lupin uses specific genes to grow root hairs and access phosphorus when it's scarce.

Mice without the Sept4/ARTS gene heal wounds better due to more stem cells that don't die easily.

Muscles and nerves that cause goosebumps also help control hair growth.

SHISA6 helps maintain certain stem cells in mouse testes by blocking signals that would otherwise cause them to differentiate.

Human skin cells produce proenkephalin, which changes with environmental factors and skin diseases.

A20 protein is crucial for normal skin and hair development.

The human type II 5α-reductase gene has a specific structure important for understanding certain medical conditions.

Cells in hair follicles help create fat cells in the skin by releasing a protein called Sonic Hedgehog.

Sphynx cats are hairless and Devon Rex cats have curly hair due to specific genetic mutations.

Hair color loss can indicate the effectiveness of a drug targeting the KIT protein in mice and humans.

A protein called CBP is found in prostate cancer and can increase the effectiveness of certain prostate cancer treatments.

The p53 protein helps control hair follicle shrinking by promoting cell death in mice.

Topical drugs and near-infrared light therapy show potential for treating alopecia.

Keratin proteins are crucial for healthy skin, but mutations can cause skin disorders with no effective treatments yet.

Maintaining DNA health in stem cells is key to preventing aging and tissue breakdown.

Abnormal Hedgehog signaling in blood cancers may help tumors grow and resist chemotherapy, suggesting potential for targeted treatments.

The document concludes that for hair and feather growth, it's better to target the environment around stem cells than the cells themselves.

The document concludes that there are no effective clinical treatments for hearing loss due to hair cell damage, but research is ongoing.

The hair follicle is a great model for research to improve hair growth treatments.

Skin fat has important roles in hair growth, skin repair, immune defense, and aging, and could be targeted for skin and hair treatments.

Blocking BMP signaling causes hair loss and disrupts hair growth cycles.

The p53 protein has complex, sometimes contradictory functions, including tumor suppression and promoting cell survival.

A deficiency in the TTC7A gene causes immune problems, gut issues, and hair loss.