research The Cellular Basis of Mechanosensory Merkel-Cell Innervation During Development
BMP signaling is essential for the development of touch domes.
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870-900 / 918 resultsresearch Cellular and Metabolic Basis for the Ichthyotic Phenotype in NIPAL4 (Ichthyin)–Deficient Canines
Mutations in NIPAL4 cause skin issues by disrupting lipid layers, but some improvement is seen with topical treatment.
research Current Treatments for Alopecia Areata
There is no cure for alopecia areata, but treatments like JAK inhibitors show promise.
research Commonalities Between COVID-19 and Radiation Injury
Some drugs may help treat both COVID-19 and radiation injury.
research Erlotinib-Induced Skin Inflammation Is IL-1 Mediated in KC-Tie2 Mice and Human Skin Organ Culture
Erlotinib causes skin inflammation through IL-1, which can be reduced by anakinra.
research Vitamin D Status in Scarring and Nonscarring Alopecia
People with certain types of hair loss, especially lichen planopilaris and telogen effluvium, as well as African Americans, Asians, and men, are more likely to have severe vitamin D deficiency.
research Interleukin 6 and STAT3 Regulate p63 Isoform Expression in Keratinocytes During Regeneration
The conclusion is that the IL-6/STAT3 activation affects p63 expression in healing wounds, which may help in hair follicle regeneration.
research Alopecia Areata After Denosumab Treatment for Osteoporosis
Denosumab treatment for osteoporosis can cause hair loss.
research Montagna Symposium 2014: Skin Aging - Molecular Mechanisms and Tissue Consequences
The symposium concluded that understanding the molecular mechanisms of skin aging could lead to better clinical practices and treatments.
research Comparison of the Acute Ultraviolet Photoresponse in Congenic Albino Hairless C57BL/6J Mice Relative to Outbred SKH1 Hairless Mice
B6.Cg-Tyr c−2J Hr hr /J mice have a stronger delayed sunburn reaction and are good for UV research.
research Brigham Eyebrow Tool for Alopecia: A Reliable Assessment of Eyebrow Alopecia Areata
The Brigham Eyebrow Tool for Alopecia is a simple and reliable way to measure eyebrow hair loss.
research A Potential Role for IL-4 and IL-13 in an Alopecia Areata–Like Phenotype: A Clinical Perspective
IL-4 and IL-13 might play a role in a type of hair loss similar to alopecia areata.
research 2-Deoxy D-Glucose Treatment Does Not Elicit a Hair Growth Response in Alopecia Areata
2-deoxy D-glucose does not help with hair regrowth in alopecia areata.
research Alopecia Areata After COVID-19 Vaccines
Some people with a history of autoimmune hair loss experienced worsening symptoms after COVID-19 vaccination.
research Multiple Basal Cell Carcinomas in a Patient with Myotonic Dystrophy Type 1
A man with myotonic dystrophy type 1 had 28 skin cancers, suggesting a link between the disease and skin cancer, emphasizing the need for sun protection and regular skin checks.
research Adverse Events in Patients Treated With Jak-Inhibitors for Alopecia Areata: A Systematic Review
JAK-inhibitors for alopecia areata are generally safe with mostly mild side effects and a low rate of treatment withdrawal.
research The Mechanisms of Anabolic Steroids, Selective Androgen Receptor Modulators, and Myostatin Inhibitors
Anabolic steroids boost muscle growth, SARMs increase muscle mass and bone density without side effects, and myostatin inhibitors block a protein that stops muscle growth, but each has potential risks.
research Anabolic and Metabolic Effects of Testosterone and Other Androgens: Direct Effects and Role of Testosterone Metabolic Products
Testosterone and its metabolites have varied effects on different body systems, especially during puberty.
research Vitamin D Levels in Patients With Seborrheic Dermatitis
People with seborrheic dermatitis often have lower vitamin D levels.
research Role of Growth Factors-Rich Plasma, Gel, and Membrane in Dermal Wound Healing and Injured Tissue Restoration and Regeneration
Growth factors-rich plasma treatments can significantly speed up wound healing and tissue regeneration.
research Use of Botulinum Toxin for Androgenic Alopecia: A Systematic Review
Botulinum toxin injections can help treat common hair loss in men, but more research is needed to confirm this and understand how it works.
research Evaluating Treatments for Male Androgenetic Alopecia: Clinical Profile and Comparative Efficacy of Platelet Rich Plasma and Minoxidil with Finasteride
Combining PRP with minoxidil and finasteride is the most effective treatment for male hair loss.
research The Relationship Between Pregnant Women Hair Loss And Ferritin Levels And Vitamin D3 In Salah Al-Din Governorate
Low vitamin D3 and ferritin levels may cause hair loss in pregnant women.
research 1,25-(OH)2D3 Promotes Hair Growth by Inhibiting NLRP3/IL-1β and HIF-1α/IL-1β Signaling Pathways
1,25-(OH)2D3 helps hair grow by blocking certain harmful signals.
research The Role of Platelet-Rich Plasma in Androgenetic Alopecia: A Systematic Review
Platelet-rich plasma may improve hair density and count in male pattern hair loss, but more high-quality research is needed.
research Expecting Scalp Hair Regrowth During Severe Alopecia Areata Treatment with Baricitinib: Insights from Patient Trajectories in Phase III Trials
Hair regrowth from severe alopecia areata treatment with baricitinib can vary, with faster results in those with shorter hair loss duration.
research Systematic Review of Mesotherapy for the Treatment of Hair Loss
Mesotherapy might improve hair growth, but more research is needed to confirm its safety and effectiveness.
research Head and Neck Restoration in Scar Alopecia: Hair Transplantation in Scalp, Eyebrows, Beard, and Mustache
Hair transplantation is effective for treating scar-related hair loss on the head and neck.
research The Spade Sign as a Pathognomonic Histopathologic Feature of Acne Keloidalis: Analysis of 33 Cases of Cicatricial Alopecia
The "spade sign" is a highly specific indicator for diagnosing acne keloidalis.
research Is the Effect Worth the Risk? The Most Common Complaints During Oral Isotretinoin Anti-Acne Therapy and Controversies Around Its Adverse Effects
Most patients on isotretinoin for acne experience mild, dose-related side effects, but the connection to depression or bowel disease is uncertain.