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Pubertal acne is linked to hormonal changes, affects quality of life, and is treated similarly to adult acne.

Using steroids can increase the risk of heart problems.

Hormones and metabolism play a complex role in prostate enlargement, and more research is needed to improve diagnosis and treatment.

Testosterone treatment can improve sexual function and bone density in women but may have adverse effects and requires more research on safety and guidelines.

Childhood obesity is rising globally due to various factors, and early prevention and healthy lifestyle changes are crucial.

Balding people may have higher heart disease risk.

A mix of Polygonatum sibiricum and Nelumbinis semen may ease menopause symptoms with fewer side effects.

Antiandrogens like flutamide are effective in treating conditions like prostate cancer and hair loss, but there's a need for more potent versions. Understanding their structure can help develop better treatments.

The document concludes that treating androgen excess needs patience, managing expectations is important, and many drugs used are not officially approved, suggesting cosmetic options for mild cases.

Nellore cattle have genetic variations linked to their adaptation to tropical environments.

The Androgen Receptor could be a target for treating diseases like cancer, but more research is needed to confirm the effectiveness of potential treatments.

New treatments for male hypogonadism are effective and should be personalized.

Testosterone and its metabolites have varied effects on different body systems, especially during puberty.

Taking Saw palmetto and Pygeum africana can change the levels of certain steroids in urine, which could cause confusion in doping tests.

PSA levels could help detect illegal steroid use in female athletes but face challenges like cost and PCOS prevalence.

Androgens and androgen receptors are important for metabolic health, affecting how the body uses glucose and fats through mitochondrial function.

Taking oral testosterone with finasteride or dutasteride doubles testosterone levels, and food slightly affects it.

Cross-sex hormone therapy is important for managing gender dysphoria and requires careful monitoring and healthcare provider education.

Special proteins are important for skin balance, healing, and aging, and affect skin stem cells.

The document concludes that there are still unknowns about the effectiveness, risks, and detection of performance-enhancing drugs, and doping remains a challenge.

The guideline provides healthcare professionals in South Africa with instructions for comprehensive, multidisciplinary gender-affirming care, including HIV prevention and treatment for transgender and gender diverse individuals.

Insulin resistance may contribute to various skin diseases and treating it could improve skin health and prevent more serious conditions.

The guideline suggests using specific criteria to diagnose PCOS, recommends various treatments for its symptoms, and advises screening for related health issues.

Women with only irregular periods or excess hair have a better hormone profile than those with full PCOS, but both groups are similar, indicating a need for better PCOS diagnosis methods.

Changes in testosterone and estrogen receptor genes can affect how men age, influencing body fat, hair patterns, and possibly leading to skin disorders.

Dutasteride, usually used for prostate issues and hair loss, could potentially treat Amyotrophic Lateral Sclerosis (ALS) due to its neuroprotective, antioxidant, and anti-inflammatory properties, but more testing is needed.

Minoxidil boosts elastin production, potentially helping skin diseases.

Celiac disease requires more than just a gluten-free diet for effective management.

TGF-β signaling is crucial for stem cell maintenance, differentiation, and has implications for cancer treatment.

Skin, hair, and nail changes can help detect eating disorders early.