research Off-Label Uses of Retinoids in Dermatology
Retinoids are effective for various skin conditions and hair loss but have serious side effects, so low doses are recommended.
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research Common Causes of Pediatric Alopecia
Hair loss in children is often caused by scalp infections, immune disorders, hair pulling, stress, and requires careful treatment due to emotional effects.
research A Kaleidoscope of Keratin Gene Expression and the Mosaic of Its Regulatory Mechanisms
Keratin protein production in cells is controlled by a complex system that changes with cell type, health, and conditions like injury or cancer.
research Autologous Platelet and Extracellular Vesicle-Rich Plasma as Therapeutic Fluid: A Review
Autologous Platelet and Extracellular Vesicle-Rich Plasma (PVRP) has potential in enhancing tissue regeneration and improving hair conditions, but its effectiveness varies due to individual differences.
research Recombinant Thrombomodulin Used to Successfully Treat Cronkhite-Canada Syndrome with Disseminated Intravascular Coagulation Due to Sepsis in a Compromised Patient
Recombinant thrombomodulin can effectively treat severe complications in Cronkhite-Canada syndrome.
research Hair and Nail Manifestations of Systemic Disease
Early baldness in men may indicate risks for obesity, metabolic syndrome, insulin resistance, and heart disease, similar to women with PCOS. Alopecia areata is often linked with autoimmune diseases and mental health issues. Certain hair disorders are due to genetic issues, and chemotherapy can cause hair loss through specific biological pathways. Iron deficiency's link to hair loss is still disputed.
research The Nutrient–Skin Connection: Diagnosing Eating Disorders Through Dermatologic Signs
Skin, hair, and nail changes can help detect eating disorders early.
research Dermatologic Manifestations of Thyroid Disease: A Literature Review
Thyroid disease can cause skin, hair, and nail problems, and treating the thyroid condition often improves these symptoms.
research Skin Manifestations of Rheumatological Diseases
Different rheumatological diseases can cause specific skin problems.
research The Keratins and Their Disorders
Mutations in keratin genes cause cell fragility and various skin disorders.
research Epidermolysis Bullosa Simplex: A Paradigm for Disorders of Tissue Fragility
Epidermolysis bullosa simplex causes easily blistered skin due to faulty skin cell proteins, leading to new treatment ideas.
research Clinical Cases of Darier-White Follicular Dyskeratosis
Darier-White disease causes skin and nail issues, starts around age 20, worsens until 40-50, and has poor treatment options.
research Oral Retinoids in Dermatology
Oral retinoids are effective for severe skin conditions but require careful use due to side effects.
research Hair and Scalp Disorders in Women of African Descent
Afro-textured hair is more fragile and prone to certain scalp conditions, requiring careful treatment and more research for effective management.
research Dermatological History and Examination
A thorough skin history and examination are essential for diagnosing and treating skin conditions effectively.
research Epidermolysis Bullosa in Animals: A Review
Epidermolysis bullosa is a genetic disease causing fragile skin and blisters in both animals and humans.
research Nail Involvement in Frontal Fibrosing Alopecia
Frontal fibrosing alopecia may affect nails and could be a type of lichen planus, treatable with certain medications.
research Adverse Reactions to Oral Retinoids: An Update
Oral retinoids can cause side effects ranging from mild to severe, including birth defects, and require careful monitoring and contraception.
research Ion Pairs of Risedronate for Transdermal Delivery and Enhanced Permeation Rate on Hairless Mouse Skin
Ion-paired risedronate significantly increases skin penetration without irritation compared to risedronate alone.
research Unraveling the Molecular Mechanisms of Hair and Nail Genodermatoses
Genetic discoveries are key for understanding, diagnosing, and treating inherited hair and nail disorders.
research Granulation Tissue Developed After Minor Trauma in a Psoriatic Patient on Long-Term Etretinate Therapy
Long-term etretinate use may cause delayed wound healing and extra tissue growth after injury.
research Light Microscopic Hair Abnormalities in Children: Retrospective Review of 119 Cases in a 10-Year Period
Over half of the children had abnormal hair under a microscope, with many having genetic hair conditions.
research Marie-Unna Hereditary Hypotrichosis
A 12-year-old boy with a rare genetic condition has progressive hair loss with no effective treatment.
research Stem Cells in the Hair Follicle and Interfollicular Epidermis of Mice Following Topical Application of Fluocinolone Acetonide
Fluocinolone acetonide slows down hair follicle stem cells but speeds up skin cell growth in mice.
research Disorders of the Skin Appendages
The document concludes that proper recognition and treatment of skin appendage disorders are important for management.
research Wound Healing: A Cellular Perspective
The document concludes that better targeted treatments are needed for wound healing, and single-cell technologies may improve cell-based therapies.
research Physiologic Skin Changes in Pregnancy
Pregnancy can cause skin darkening, varicose veins, more sweating, hair growth, hair loss after birth, nail changes, and gum inflammation.
research Effects of Turmeric (Curcuma Longa) on Skin Health: A Systematic Review of the Clinical Evidence
Turmeric may have benefits for skin health, but more research is needed to confirm its effectiveness.
research Androgen Sensitivity Gateway to COVID-19 Disease Severity
Men's sensitivity to male hormones might affect how severe COVID-19 gets for them.
research Physiological Changes in the Skin During Pregnancy
Pregnancy can cause skin pigmentation, stretch marks, and changes in hair, nails, and sweat glands, with most resolving after birth.