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This study found that the overexpression of the lncRNA HOTTIP in glioma cells increased resistance to the chemotherapy drug temozolomide, suggesting a key role for miR-10b and EMT processes in this resistance.

In a mouse model of chemotherapy-induced alopecia, this study found that enhancing ETV2 expression improved angiogenesis and hair regrowth following 5-fluorouracil treatment.

This study found that the absence of the stress-responsive protein Sesn2 increased hair cell susceptibility to gentamicin in the inner ear, indicating Sesn2's potential protective role against aminoglycoside-induced damage.

This study successfully established Tsc2-deficient embryonic stem cells from Eker rats and found these cells have distinct gene expression compared to non-mutant cells, which could help identify new therapeutic targets for TSC-related pathogenesis.

This study reported that a new coating made with delaminated Ti₃C₂ MXene nano-sheets and a tea-derived compound effectively protects hair keratin from damage by providing UV screening, thermal dissipation, and antioxidation, while also enhancing mechanical strength and restoring wettability.

This study found that topical application of mitochondrial electron transport chain inhibitors stimulated hair follicle stem cell activation and hair regrowth in aged mice by promoting lactate production.

Sirolimus can reduce tumor cell size in TSC-related skin tumors, but continuous treatment is needed to maintain benefits.

This study found that Carthamus tinctorius floret ethanolic extract stimulated melanogenesis in B16F10 murine melanoma cells without cytotoxicity, suggesting its potential as a treatment for gray hair.

This study evaluated local treatment with minoxidil 2% watery solution in patients with androgenetic alopecia but did not report detailed clinical outcomes.

This study found that the tetracycline-regulated transcription system effectively controls conditional gene expression in the mouse epidermis, allowing suppression and activation of specific genes with doxycycline.

This study indicates that a helminth-derived protein, TGF-β mimic, may accelerate wound healing and promote regenerative processes in skin tissue by interacting with TGF-β receptors.

This study presented at the ASCO Annual Meeting reported that the epidermal growth factor receptor antibody ABX-EGF showed preliminary efficacy in renal cell cancer patients, with tolerable side effects, while bortezomib demonstrated clinical benefit in a significant proportion of multiple myeloma patients.

In this randomized, placebo-controlled study, Titagen® was found to improve skin, hair, and nail health in adults consuming 5g daily, and reduce pain and improve quality of life for osteoarthritis patients taking 10g daily, without related adverse events.

In this study, researchers found two non-synonymous SNPs in the TERT gene associated with mean wool staple strength in sheep, suggesting TERT as a potential candidate gene for improving wool traits.

This case report describes a successful treatment of sarcoidal foreign body reactions caused by permanent makeup ink with local steroid injections, while also identifying the involvement of M2 macrophages in the reaction.

In this study, researchers found that BST2 expression is significantly upregulated in skin sections of mice with alopecia areata, implicating BST2's role in the disease pathogenesis through the action of epidermal γδ T cells and macrophages.

In this clinical study involving individuals with localized alopecia areata, TrA injections were found to significantly outperform MTX, leading to better hair regrowth and higher patient satisfaction, though both treatments had similar mild side effects.

This case report describes an unusual variant of Turner Syndrome in a 20-year-old female that required comprehensive medical and psychological care, including hormonal therapy that resolved symptoms like alopecia.

This observational study reviewed thyroid eye disease patients treated with teprotumumab at one center, reporting common side effects like fatigue and dry eye symptoms, with serious adverse events including two cases of blood clots and one pulmonary embolism.

This study found that combining hair transplantation with platelet-rich plasma led to significantly better outcomes, such as reduced hair loss area and increased hair regeneration, compared to hair transplantation alone in patients with androgenic alopecia.

This study found that mycophenolate mofetil was well tolerated and effective as a second-line treatment for autoimmune hepatitis in patients who were intolerant to azathioprine.

This study reported that both topical methotrexate 1% gel and minoxidil 5% gel were effective in treating localized alopecia areata, with no significant differences in efficacy between the two treatments.

This study found that mTOR signaling plays a crucial role in activating hair follicle stem cells by balancing BMP-mediated repression, essential for hair regeneration.

In this study, the researchers reported that minoxidil-loaded transfersomes using a cyclodextrin strategy significantly increased drug stability, skin permeation, and hair regrowth in a mouse model of androgenetic alopecia compared to traditional formulations and commercial tinctures.

In this study, TASP0382088 showed potent selective inhibition of the ALK5 receptor, significantly reducing Smad2 phosphorylation in mouse skin following topical application.

The authors reported that 4-O-methylhonokiol decreased TGF-β1-induced cell cycle arrest and oxidative stress markers in human keratinocyte cells, suggesting a potential protective role in TGF-β1-mediated cell cycle regulation.

In this study, the medicated oil made from Martynia annua leaves showed strong hair growth-promoting activity in a mouse model of testosterone-induced alopecia, potentially outperforming the standard treatment, finasteride.

This study found that topical application of triiodothyronine (T3) can induce the transition of hair follicles from the telogen to the anagen phase in mice and stimulate hair shaft growth in vitro.

Long-standing benign tumors can become cancerous, especially in people with weakened immune systems.

This study found that a TYK2 inhibitor, BMS-986202, may restore immune privilege in hair follicles and promote hair regrowth in a humanized alopecia areata mouse model by inhibiting IL-12-mediated signaling.