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The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

The document concludes that future heart disease research should account for sex-specific differences to improve diagnosis, treatment, and outcomes.

The current system can't fully test all combination treatments, so alternative methods and regulatory flexibility are needed.

Aldesleukin can treat certain cancers and increase HIV patient CD4+ counts but often causes severe side effects.

The AUTS2 gene is linked to neurological disorders and may affect human brain development and cognition.

Discoid Lupus Erythematosus often causes scarring hair loss, is influenced by genetics and environment, and requires early treatment to prevent worsening.

Hair health is influenced by genetics, aging, and environmental factors, with proper care needed to maintain it.

UVB radiation harms hair growth and health, causing cell death and other changes in human hair follicles.

PCOS affects nearly 25% of female medical and dental students, impacting their academic and social lives.

MEL-A from soybean oil can boost fibroblast and papilla cells, potentially aiding hair growth.

The new palladium catalyst is effective and reusable for making pharmaceutical ingredients.

An elderly man with skin amyloidosis and abnormal blood proteins was monitored without finding widespread disease after 18 months.

Combining cantigi and henna leaf extracts boosts antioxidant activity.

Certain factors like patchy hair loss at the back of the head, being female, and younger age at diagnosis can lead to a worse outcome for alopecia areata.

Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.

Dienogest combined with ethinylestradiol is a highly effective birth control that improves menstrual symptoms and has manageable side effects.

New treatments for Hepatitis C show promise but need more research to confirm their safety and effectiveness for clinical use.

New methods to make oxasteroids show promise for medical treatments like osteoporosis and breast cancer.

Aging alone rarely causes significant hair loss; hormones are a bigger factor.

People with HIV and low T cell counts have more hair and scalp problems.

Minoxidil use during pregnancy may cause fetal harm.

Runx1 controls fat-related genes important for normal and cancer cell growth, affecting skin and hair cell behavior.

Nellore cattle have genetic variations linked to their adaptation to tropical environments.

Testosterone implants in women require pharmacological dosing to be effective and are generally safe and well-tolerated.

Spironolactone may help reduce hair loss in androgenic alopecia.

High and low doses of prednisolone helped 62% of children with severe alopecia regrow hair with some weight gain and mild acne as side effects.

Demodex mites rarely cause scalp infections leading to hair loss, but when they do, treatment is effective.

Mycophenolate mofetil helped reduce steroid use in treating a dog's autoimmune skin disease.

In 2017, a new method was created to efficiently produce a topical antiandrogen, a compound used to treat excess sebum and acne, with a high yield and purity.

Minoxidil dissolves better in propylene glycol and water as temperature and propylene glycol amount increase.