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Low doses of some substances can be beneficial, while high doses can be harmful or toxic.

Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.

Cepharanthine is a well-tolerated drug with multiple medical uses, including anti-inflammatory and anti-cancer properties.

Cytokeratin 19 and cytokeratin 15 are key markers for monitoring the quality and self-renewing potential of engineered skin.

Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.

The document concludes that while significant progress has been made in understanding skin biology and stem cells, more research is needed to fully understand their interactions with their environment.

The hydrogel with a 1:3 ratio of hydroxyethyl cellulose to hyaluronic acid is effective for delivering drugs through the skin to treat acne.

The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.

JAK inhibitors help with skin conditions but need more research on dosing and safety.

Scientists turned rat thymus cells into stem cells that can help repair skin and hair.

Some drugs can cause skin, nail, and hair problems, which are important for healthcare professionals to recognize and report.

Fullerenes show potential in skin care but need more safety research.

Androgens can both stimulate and cause hair loss, and understanding their effects is key to treating hair disorders.

Different soft tissue fillers can cause various skin reactions; biodegradable fillers are safer and non-biodegradable ones like silicone can lead to long-term problems.

Minoxidil effectively treats severe hypertension but may cause side effects, so careful monitoring is needed.

Alopecia areata treatment varies, with no optimal method established yet.

Treatments for permanent hair loss from scarring aim to stop further loss, not regrow hair, and vary by condition, with partial success common.

Obesity increases the risk of developing polycystic ovary syndrome, and weight loss can improve the condition.

Wool follicles are complex, involving interactions between different cell types and structures.

Targeted cancer therapies often cause skin reactions, so dermatologists must manage these effects.

Minoxidil helps hair growth by activating the β-catenin pathway.

The document concludes that specific itchy skin diseases during pregnancy have varying fetal risks and treatments, including corticosteroids and other medications.

Layer-by-Layer self-assembly is promising for biomedical uses like tissue engineering and cell therapy, but challenges remain in material safety and process optimization.

MDP hydrogel heals wounds faster and better than other treatments in diabetic mice.

Mammals might fail to regenerate not because they lack the right cells, but because of how cells respond to their surroundings, and changing this environment could enhance regeneration.

Mannosylerythritol lipids are good for skin and hair care products.

Treatments for melanin disorders exist, but more effective options needed.

Certain types of T cells are essential for healthy skin and play a role in skin diseases, but more research is needed to improve treatments.

Nanoparticle systems make cancer treatment less toxic.

Despite progress, better treatments and understanding are needed for the high rates of long-term issues and deaths linked to eating disorders.