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Scientists successfully created and analyzed the structure of a part of the human androgen receptor with specific modulators and a peptide to understand how it binds differently in various tissues.

L-PGDS has specific binding sites for its functions and could help in drug delivery system design.

Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.

Scientists improved an enzyme to better produce a hair growth-promoting chemical from an immunosuppressant.

Gene therapy with the Math1 gene helped regenerate balance-related cells and improve balance in mice.

The structure of SRD5A reveals how it reduces steroids, aiding drug design for related health conditions.

Scalp cooling can help prevent chemotherapy-induced hair loss with a 50-90% success rate and is safe for patients.

FGF9 controls which receptors it binds to through a process where two FGF9 molecules join, and changes in FGF9 can lead to incorrect receptor activation.

Using CDK inhibitors on rats showed a reduction in chemotherapy-caused hair loss, but later experiments could not repeat these results.

ΔNp63α stops TAp73β from working in skin cancer by blocking its access to specific genes, not by directly interacting with it.

The research explains how a human enzyme binds and processes its substrate, which could relate to its role in biological functions and hair loss.

The study concludes that certain domains in Clostridium histolyticum enzymes are structurally unique, bind calcium to become more stable, and play distinct roles in breaking down collagen, with potential applications in medicine and drug delivery.

Mutations in the enzyme don't significantly change how it binds to its specific substances.

Get3d protein helps maintain photosynthesis in plants and photosynthetic bacteria.

Minoxidil can reduce functions related to androgen receptors.

New treatments for ichthyosis, like protein replacement and gene therapy, show promise and may become standard care.

Newborn screening and gene therapy are expected to improve outcomes for Omenn syndrome patients.

Skin aging is caused by stem cell damage and can potentially be delayed with treatments like antioxidants and stem cell therapy.

Lizards can regrow their tails, and studying this process helps understand scar-free healing and limb regeneration.

Estrogen loss during menopause worsens skin health, but hormone replacement therapy may improve it, though more research is needed.

New treatments targeting skin stem cells show promise for skin repair, anti-aging, and cancer therapy.

Women have a higher risk of blood clots from hormonal factors and need careful treatment, especially during pregnancy.

Estrogens can improve skin aging but carry risks; more research is needed on safer treatments.

New treatments and early diagnosis methods for permanent hair loss due to scar tissue are important for managing its psychological effects.

Experts met to improve care for ichthyosis patients in Spain.

There are many treatments for permanent hair loss disorders, but their effectiveness varies and there's no clear best option.

The document concludes that sex hormones are crucial for mammalian reproduction, health, and behavior, and require more research for therapeutic use.

Skin stem cells are crucial for maintaining and repairing the skin and hair, using a complex mix of signals to do so.

Sex and stress steroids quickly change brain cell structures in the hippocampus.

Testosterone plays a big role in heart and nervous system damage caused by inflammation in male rats, suggesting that blocking testosterone production could help manage this condition.