research The Stem Cell Quiescence and Niche Signaling Is Disturbed in the Hair Follicle of the Hairpoor Mouse, an MUHH Model Mouse
Disrupted stem cell signals in hairpoor mice cause hair loss.
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960-990 / 1000+ resultsresearch Dual-Mode Vasodilator M119 Delivery to Hair Follicle via Dissolving Microneedle for Advanced Alopecia Treatment
A new microneedle system effectively delivers a vasodilator to hair follicles, promoting hair growth better than current treatments.
research Psychiatric Morbidity in Children and Adolescents with Dermatological Disorders
Kids with skin problems are more likely to have mental health issues.
research Mapping the Molecular and Structural Specialization of the Skin Basement Membrane for Inter-Tissue Interactions
The skin's basement membrane is specially designed to support different types of connections between skin layers and hair follicles.
research Ovarian Vein Sampling, and Serum and Urine Testosterone Monitoring in Ovarian Leydig Cell Tumors: A Report of Two Cases
Ovarian vein sampling helped diagnose rare ovarian tumors causing high testosterone, and surgery to remove the tumors lowered the testosterone levels.
research The Effects of Oral 5-Alpha Reductase Inhibitors on Penile Intracavernosal Pressures and Penile Morphology in a Rat Model
Oral finasteride and dutasteride may negatively affect erectile function in rats.
research The Mossman–Pacey Paradox: Evolutionary Contradictions in Male Enhancement Treatments
Men using steroids or finasteride to look more attractive may harm their fertility and sexual function, creating a paradox where they seem fit but may be less able to reproduce.
research Understanding Skin Morphogenesis Across Developmental, Regenerative, and Evolutionary Levels
The article concludes that studying how skin forms is key to understanding skin diseases and improving regenerative medicine.
research Molecular Profiling of Frontal Fibrosing Alopecia Reveals TH1 and JAK-STAT Up-Regulation with No Suppression of Hair Keratins
Frontal fibrosing alopecia shows increased inflammation and JAK-STAT pathway activity without reduced hair proteins.
research High-Throughput and Direct Measurement of Androgen Levels Using Turbulent Flow Chromatography Liquid Chromatography-Triple Quadrupole Mass Spectrometry to Discover Chemicals That Modulate Dihydrotestosterone Production in Human Prostate Cancer Cells
Researchers found four natural compounds that can change DHT levels in prostate cancer cells.
research Generation of iPS-Derived Model Cells for Analyses of Hair Shaft Differentiation
Researchers created a mouse cell line to study hair growth and test hair growth drugs.
research Comparison of Effects on Gene Expression Activity of Low-Molecular-Weight Lychee Fruit Polyphenol (Oligonol), Adenosine, and Minoxidil in Human Dermal Papilla Cells
Lychee fruit polyphenol (Oligonol®) may regulate genes linked to cell growth and inflammation in human scalp cells.
research Mycophenolate Mofetil in Induction and Maintenance Therapy for Juvenile Onset Severe Lupus Nephritis
Mycophenolate mofetil is effective for treating severe lupus nephritis in children.
research The Most Efficient Follicular Regenerating Unit and the Smallest Follicular Regenerating Unit: Potential Treatments for Hair Loss
Identifying specific hair follicle parts could lead to better hair loss treatments.
research A Hierarchical Bayesian Hidden Markov Model for Multi-Dimensional Discrete Data
Non-denatured soybean extracts are effective for skin care, offering skin lightening, anti-aging, and UV protection benefits.
research Seasonal Moulting in Adult Male Raccoon Dog (Nyctereutes Procyonoides)
Adult male raccoon dogs shed their winter fur in spring and grow new fur for winter in autumn.
research Stabilization of Epithelial Beta-Catenin Compromises Mammary Cell Fate Acquisition and Branching Morphogenesis
Keeping β-catenin levels high in mammary cells disrupts their development and branching.
research Convergent Decay of Skin-Specific Gene Modules in Pangolins
Pangolins have lost some skin-related genes, but kept others, showing complex skin evolution.
research Peripheral Neuroprotective and Immunomodulatory Effects of 5α-Reductase Inhibitors in Parkinson's Disease Models
Dutasteride may help protect neurons and reduce inflammation in Parkinson's disease.
research Mycophenolate Mofetil in the Management of Lichen Planus Pigmentosus in a Woman with Frontal Fibrosing Alopecia
Mycophenolate mofetil effectively improved skin pigmentation and itching in a woman with lichen planus pigmentosus and frontal fibrosing alopecia.
research Development and Validation of Androgen-Induced Hair Loss and Anagen Induction Mouse Models for Pharmacological Evaluation of Anti-Androgenic Agents
The mouse models are effective for testing new hair loss treatments.
research The Evolution of Emerging Nanovesicle Technologies for Enhanced Delivery of Molecules into and Across the Skin
Nanovesicles improve drug delivery through the skin, offering better treatment outcomes and fewer side effects.
research Comparing Current Therapeutic Modalities of Androgenic Alopecia: A Literature Review of Clinical Trials
Some treatments for hereditary hair loss are effective but vary in results and side effects; new therapies show promise but need more research.
research In Quest of the Mysterious Holistic Vedic Herb Bacopa Monnieri (L.) Pennell
Bacopa monnieri, or Brahmi, is a traditional herb that may improve memory and treat various conditions, but more research is needed.
research DKK1-Targeting Cholesterol-Modified siRNA Implication in Hair Growth Regulation
Blocking DKK1 with siRNA can improve hair growth.
research Inhibition of a Signaling Modality Within the Gp130 Receptor Enhances Tissue Regeneration and Mitigates Osteoarthritis
Blocking a certain signal in the gp130 receptor can improve tissue healing and lessen osteoarthritis symptoms.
research In Silico Modelling of Transdermal Delivery of Macromolecule Drugs Assisted by a Skin Stretching Hypobaric Device
The simulation showed that hypobaric pressure improves drug delivery through the skin, but stretching alone doesn't fully explain the increase.
research Acetate Meliorates Depressive-Like Behaviour in a Rat Model of PCOS Through Suppression of HDAC2 Expression and DNA Methylation
Acetate helps reduce depression in rats with PCOS by lowering specific gene expression and DNA changes in the brain.
research Long COVID: Current Status in Japan and Knowledge About Its Molecular Background
Long COVID in Japan involves persistent symptoms like fatigue and may be caused by lasting organ damage and prolonged inflammation, with vaccination as a potential treatment.
research Non-Invasive Monitoring of Low Molecular Weight Biomarkers Relevant to Skin Inflammation and Cancer
Non-invasive methods can effectively monitor skin inflammation and cancer biomarkers.