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BI 2536 had limited effectiveness against several advanced cancers and caused significant side effects.

The document tests knowledge and decision-making in hematology through multiple-choice questions.

The document provides 70 multiple choice questions to improve haematology skills.

Blocking IL-1 could help treat some hair loss conditions; alopecia affects liver detox systems; spironolactone is better than finasteride for female hair growth; focusing on the catagen hair phase could lead to new alopecia treatments.

A man had a non-cancerous, fast-growing skin lump on his arm that was removed with surgery.

Some brain cancer cells avoid immune system detection, and certain treatments could target this to slow their growth; also, certain fat cell precursors help regenerate hair and skin after injury.

Zidovudine may cause hair loss in advanced-stage HIV patients.

Some drugs can cause hair loss, and stopping these drugs often leads to hair regrowth.

A man got six skin cancers within a year after a cell transplant for leukemia but was cancer-free 32 months later; skin checks are important post-transplant.

Cancer therapy can cause various skin problems, including hair loss, skin darkening, painful hand-foot syndrome, and severe skin damage.

Stem cell niches are adaptable and key for tissue maintenance and repair.

Minoxidil promotes hair regrowth in early baldness stages and prevents baldness in non-bald scalps.

The growth of the Epstein-Barr virus in the patient's cells was linked to the worsening of her lymphoma.

The medication lopinavir-ritonavir may cause severe hair loss.

Photodynamic therapy may not work for erythroplasia of Queyrat and could lead to invasive squamous cell carcinoma.

Mesotherapy is more effective than topical spray for female hair loss treatment.

Chemotherapy with docetaxel can cause painful nail and skin side effects that may lead to stopping treatment.

Finasteride may effectively treat hair loss in Klinefelter Syndrome patients.

African spiny mice can regenerate skin, hair, and cartilage, but not muscle, and their unique abilities could be useful for regenerative medicine.

CDP is crucial for lung and hair follicle cell development.

Cathepsin L is essential for normal hair growth and development.

The research identified various cell types in mouse and human teeth, which could help in developing dental regenerative treatments.

Mutant CDP/Cux protein causes hair defects and reduced male fertility in mice.

Wool follicles are complex, involving interactions between different cell types and structures.

Inherited ichthyoses cause widespread skin scaling and thickening due to gene mutations.

Hair shedding is an active process that could be targeted to treat hair loss.

The document concludes that proper diagnosis and FDA-approved treatments for different types of hair loss exist, but treatments for severe cases often fail and future improvements may focus on hair follicle stem cells.

Mice lacking a key DNA methylation enzyme in skin cells have a lower chance of activating stem cells necessary for hair growth, leading to progressive hair loss.

S100A4 and S100A6 proteins may activate stem cells for hair follicle regeneration and could be potential targets for hair loss treatments.

HFMs can help study hair growth and test potential hair growth drugs.