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In this review, researchers critically examine contemporary treatments for androgenetic alopecia, emphasizing advanced drug delivery systems, regenerative medicine, and emerging molecular targets, while identifying significant gaps that hinder translating these innovations into clinical practice.

This study reports that brief exposure to low intensity and low frequency ultrasound was able to transiently break cellular microtubules and mitigate hair follicle damage, suggesting a potential method to prevent hair loss during chemotherapy with taxanes like paclitaxel.

This study suggests that black ginseng concentrate protects human follicle dermal papilla cells against oxidative stress, potentially offering a natural approach to prevent cellular dysfunction linked to hair loss.

This study reviewed current scientific evidence on how scalp microbiome alterations may affect hair growth, citing connections to inflammatory and immune processes and suggesting potential for therapeutic targeting, though further studies are needed to confirm clinical applications.

This review synthesizes preclinical evidence suggesting that Centella asiatica may extend healthspan by modulating aging hallmarks, enhancing DNA repair, improving mitochondrial function, and reducing inflammation and oxidative stress, potentially paving the way for future gerotherapeutic strategies.

In this study, researchers found that parasitic dermatitis in dogs is predominantly caused by ectoparasites like fleas and mites, with flea allergy dermatitis being particularly prevalent, and noted that diagnosis typically relies on laboratory methods, while treatments involve insectoacaricidal drugs and prevention strategies.

This study evaluated an in vitro inhalation method to assess the toxicological impacts of aerosols from heated hair products, revealing significant differences in cellular stress and IL-8 release among different test materials, which may help in developing safer products.

This case report suggests that Post-Finasteride Syndrome may involve a sustained imbalance in gut bacteria, with fermenting and hydrogen sulphide-producing bacteria disrupting hormone and mitochondrial functions.

This case report proposes that Post-Finasteride Syndrome might be sustained by specific microbes in the small intestine affecting hormone excretion and mitochondrial function, warranting further investigation in a larger cohort.

In this study, gold nanoparticle-conjugated curcumin and thymoquinone formulations were more effective against melanoma cells in 3D bioprinted scaffolds than free or co-administered phytochemicals, sustaining stress responses and overcoming tumor adaptation barriers.

In this case report, a young goat with mixed ectoparasitic infestations including Psoroptes spp. showed significant clinical improvement and resolution of skin lesions after treatment with ivermectin-based therapy and supportive care, illustrating the importance of early diagnosis and comprehensive management for recovery.

This study reviews melatonin's diverse roles in dermatology, highlighting its potential to protect skin from UV damage and oxidative stress, enhance DNA repair, and influence hair follicle cycling, suggesting therapeutic applications in skin care and hair renewal.

This review discusses the mechanisms, scientific support, and FDA clearance of photobiomodulation mask devices but reports no new research findings.

This study found that targeting peroxisomal dysfunction with catalytic nanozymes enhanced hair follicle regeneration and outperformed minoxidil in promoting hair growth and maintaining efficacy in immunodeficient mice.

This review highlights that iron deficiency is a significant yet often overlooked contributor to the development of immune-mediated inflammatory skin diseases, suggesting that iron dysregulation may drive inflammation and metabolic imbalances in conditions like psoriasis and atopic dermatitis.

This paper proposes a novel theory that certain symptoms of Post-Finasteride Syndrome may be caused by an overgrowth of hydrogen sulphide-producing bacteria in the small intestine, which acts as a mitochondrial toxin, with implications for treatment targeting the gut microbiome.

This theoretical paper proposes that a subset of Post-Finasteride Syndrome cases may be driven by a gut-derived toxic process involving hydrogen sulphide-producing bacteria, suggesting that the small intestinal microbiome could be a potential target for treating this condition.

This study found that upcycled postbiotic cell-free supernatants from Limosilactobacillus fermentum MG901 and MG4237 protected human dermal papilla cells from oxidative stress, enhancing wound-healing capacity and mitochondrial function, suggesting potential as a sustainable cosmetic ingredient for hair loss alleviation.

This study found that 3-hydroxypropionic acid improved the function of hair follicle cells under oxidative stress, suggesting potential as a treatment for stress-related hair loss.

This narrative review summarizes evidence on NAD⁺ biosynthesis and turnover, highlighting that while NAD⁺ precursors like NR and NMN consistently boost NAD⁺ levels in preclinical and human studies, clinical outcome results remain varied, indicating a need for more standardized human trials.

In this study, researchers found that sesamin, a component of sesamum, modulated the AR-MAPK-Wnt signaling pathway in DHT-stimulated HaCaT keratinocytes, demonstrating potential multi-target activity against molecular events in androgenetic alopecia.

This research observed that Salvianolic acid B (Sal B) significantly promoted hair regeneration in vivo and in vitro, outperforming minoxidil in a mouse model of androgenetic alopecia, by activating Wnt/β-catenin and mTORC2/Akt pathways and upregulating MMPs and MAPKs.

In this study, researchers synthesized silver nanoparticles using an extract from Mitracarpus scaber and found them to have significant hepatoprotective and anti-hyperplastic effects in rats, suggesting potential for treating liver injury and benign prostatic hyperplasia.

This study found that silver nanoparticles synthesized using Mitracarpus scaber extract showed potential hepatoprotective and anti-hyperplastic effects in rats, suggesting novel therapeutic strategies for managing liver injury and benign prostatic hyperplasia.

This study found that the 15-PGDH inhibitor DPP improved endothelial function in hair-related cells exposed to DHT by reducing oxidative stress and enhancing angiogenic capacity.

This review synthesizes recent molecular and preclinical advances in alopecia areata and androgenetic alopecia, highlighting how interventions targeting specific intracellular signaling pathways and utilizing stem cell technologies can support precision regrowth and structural follicle reconstruction.

In this preprint, an integrative regenerative protocol involving microneedling, plant-derived exosomes, and other therapies was used to treat androgenetic alopecia in an elderly woman, resulting in improved hair density and scalp coverage.

This preprint reports meaningful improvements in hair density and scalp coverage in an elderly female with androgenetic alopecia treated through an integrative regenerative protocol, involving microneedling and plant-derived exosomes, among other non-pharmacological interventions focusing on cellular senescence pathways.

In this laboratory study, α-mangostin was found to significantly reduce melanin content and downregulate pigmentation-related genes in cultured skin and B16F10 cells, suggesting potential application as a natural whitening agent in sunscreen development.

In this study, researchers found that oxidative stress and mitochondrial dysfunction are correlated with the severity of both androgenetic alopecia and alopecia areata, revealing specific differences between alopecia forms, which may serve as important pathogenetic and prognostic indicators.