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The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

New hormonal contraceptives are safer, have fewer side effects, and offer health benefits for women.

Excessive hair growth in women often has no known cause and is not linked to race or other hormonal symptoms.

The document concludes that research on sulfatase inhibitors should continue due to their potential in treating various diseases, despite some clinical trial failures.

Androgens like testosterone are important hormones for both men and women, made differently in each sex and affecting the body by regulating genes and quick interactions with cell components.

Certain genetic variations are linked to increased androgen levels in PCOS, but more research is needed to understand these connections fully.

Spironolactone may help enlarge a small breast linked to Becker's nevus.

Cholesterol balance is important for hair health, and problems with it can lead to hair loss conditions.

Sex hormones affect hair and feather growth and may help manage alopecia and hormone-dependent cancers.

Local skin glucocorticoid production is crucial for healthy skin, and its disruption can lead to skin diseases.

Finasteride may cause lasting sexual, mental, and physical symptoms; use with caution.

Testosterone is crucial for development, growth, and various body functions in mammals.

Men with severe early-onset baldness may have worse heart artery function and stiffer arteries if they have high blood pressure.

Minoxidil can cause a rare eye condition, but it was successfully treated with oral Eplerenone in one case.

Licorice has many health benefits but more research is needed to fully understand them.

Copper deficiency may cause hair loss, and treating it could involve nutrition and hormones.

Women with non-classic congenital adrenal hyperplasia have higher risk for heart and metabolic problems.

Traditional Chinese medicinal foods may help manage long-term post-COVID symptoms.

Excess androgens may cause PCOS, not just be a symptom.

A patient produced cortisol after adrenalectomy, possibly due to residual tissue or other body parts making steroids.

Different types of hair loss in dogs and cats have various causes and treatments, with outcomes ranging from good to uncertain.

Alopecia in animals can be hereditary, congenital, or acquired, with treatments and outcomes varying widely.

Using β-cyclodextrin derivatives improves the solubility and bioavailability of steroidal drugs.

Cabergoline helped a boy with Cushing disease get better after surgery and radiotherapy didn't work.

Understanding how DHT works is important for diagnosing and treating hormone-related disorders.

Corticosteroid therapy for alopecia areata can cause severe hip bone damage.

Canrenone effectively reduced hair growth and testosterone levels in women with excessive hairiness.

Certain genetic variants reduce enzyme activity, contributing to non-classic congenital adrenal hyperplasia.

Certain genetic variants impair enzyme activity, contributing to non-classic congenital adrenal hyperplasia.

Standard intralesional corticosteroids are the best treatment for patchy alopecia areata.