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The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

Doxil showed some effectiveness against advanced prostate cancer but caused severe side effects at higher doses.

The document concludes that research on sulfatase inhibitors should continue due to their potential in treating various diseases, despite some clinical trial failures.

Cell polarity signaling controls tissue mechanics and cell fate, with complex interactions and varying pathways across species.

Certain inhibitors can potentially treat prostate cancer and other hormone-dependent conditions by controlling sex hormone levels in cells.

The article concludes that hair loss is a common side effect of drugs treating skin cancer by blocking the hedgehog pathway, but treatment should continue, and more selective drugs might prevent this side effect.

Semecarpus anacardium leaf extracts may offer safe, effective cancer treatment alternatives.

C60 fullerenes can alter protein function and may help develop new disease inhibitors.

Pemetrexed is as effective as docetaxel but has fewer side effects for treating nonsmall-cell lung cancer after EGFR-TKI therapy failure.

Rapamycin treatment helps with mitochondrial disease by reducing PKC levels.

Feather patterns are influenced by enhancers and chromatin looping, and the structure of protein complexes important for hair growth has been detailed.

Personalized treatment plans combining natural and synthetic approaches are important for managing alopecia effectively.

KIF18B is important for correctly positioning cell division machinery in skin cells, affecting hair follicle development.

Certain herbal compounds, especially from bitter melon, can inhibit cancer growth and promote hair growth by blocking PAK1.

Targeting colon cancer stem cells might lead to better treatment results.

The new assay can track and measure melanosome transfer between skin cells, confirming filopodia's role in this process.

Retinoids increase steroid sulfatase activity in leukemia cells through RARα/RXR and involves certain pathways like phosphoinositide 3-kinase and ERK-MAP kinase.

Understanding drug interactions, side effects, and patient-specific factors is crucial for effective dermatological care.

Combination pharmacotherapy is generally more effective for treating keloids and hypertrophic scars.

Skin cell behavior is influenced by the tightness of nearby cells, affecting their growth and development.

New treatments for non-small cell lung cancer are being tested, with some already in use, focusing on immune response and targeting cancer cells, but side effects vary.

Enzymes are classified into six types and are essential for many biological processes, with only a few targeted by drugs.

Mitochondrial Complex I reduces inflammation and increases bone breakdown by affecting certain immune cells.

Anticancer drugs like methotrexate and trimetrexate could be effective and safe for treating malaria at low doses.

Using protein degradation to fight cancer drug resistance shows promise but needs more precise targeting and fewer side effects.

PFS and PSSD are similar conditions with persistent sexual dysfunction after stopping medication.

Scalp cooling therapy helps preserve hair during chemotherapy for most patients.

MIM is crucial for hair follicle formation and regeneration by controlling cilia formation and hedgehog signaling through its interaction with Cortactin and Src.

Mice studies show that Protein Phosphatase 2A is crucial for cell growth, development, and disease prevention.

Cannabinoids may help treat chronic and chemotherapy-induced neuropathic pain, but more research is needed to confirm their effectiveness and safety.