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In this review, it is discussed how mesenchymal stem cell aggregation plays a crucial role in organ development and has potential applications in organ regeneration through tissue engineering.

This study introduces a five-modal microscopy technique that allows label-free, in vivo observation and quantitative analysis of various wound healing processes.

This study reveals that somatosensory neurons in mouse skin exhibit structural plasticity during hair-follicle regeneration, which may temporarily impair the reliability of encoding gentle touch.

Miniaturized hair follicles in androgenetic alopecia show abnormal mitochondrial activity and damage.

In this study, researchers demonstrated that the expression of the oncogene SmoM2 leads to basal cell carcinoma in the ear epidermis of mice but not in the back skin, with differences in susceptibility linked to the composition of the extracellular matrix.

This study found that epidermal stem cells in nonglabrous skin are connected to the distal end of the arrector pili muscle, which may play a role in epidermal renewal and wound healing.

This study found that fibroblasts from highly regenerative mammals, such as spiny mice and rabbits, exhibit unique metabolic characteristics, including a preference for glycolysis and specific mitochondrial features, which may contribute to their resistance to oxidative stress and support tissue regeneration.

This study explored the structure and keratin composition of marsupial hairs, finding similarities in keratin localization to hairs in placental mammals, and highlighting potential roles of trichohyalin and transglutaminase during hair development and shedding.

This review discusses how polymers can be customized to develop biomaterials that mimic the extracellular matrix, exploring their potential in biomedical and biotechnological applications by triggering cell functions similar to natural physiological systems.

This study found that using a microwell array device to expand hair follicle stem cells in Matrigel significantly increased cell numbers and enhanced hair regeneration in mice.

This study reports that tissue-engineered skin using ES cell-derived epidermal stem cells and collagen sponge successfully healed full thickness skin defects in mice, forming epidermis and structures resembling glands and hair follicles.

This study found that two microRNAs, oar-miR-23b and oar-miR-133, inhibit the development of hair follicles in superfine wool sheep by targeting genes involved in key signaling pathways, suggesting their potential use as molecular markers for breeding fine wool sheep.

This study shows for the first time that onychomatricoma can recapitulate the entire nail unit with differentiation toward the nail bed and isthmus, identifying new histopathological and immunohistochemical features.

In this study, researchers developed a photocurable polyurethane resin for 3D printing, creating high-resolution elastomeric microwell arrays that effectively promote uniform spheroid formation and growth of A549 cells, which could aid in disease modeling and organoid research.

This study reported the development of a workflow that combines SIMS and X-ray elemental mapping techniques for multimodal imaging at the single cell level, successfully applied to visualize elements, metals, and lipids in porcine skin without loss or delocalization.

This study observed increased metallothionein expression in regenerating liver and hyperplastic mouse skin, suggesting a potential role in cellular proliferation and differentiation.

This study examined the clinicopathologic features of mesothelioma of the tunica vaginalis testis in 14 patients, finding that the disease mostly presented as epithelioid type, with a propensity for high-grade tumors, and BAP1 and MTAP loss was uncommon.

This study used multi-scale hybrid models to explore how signaling factors affect skin wound healing and embryo development, suggesting that different levels of fibrin clot density influence scar formation.

In this research, investigators used in vitro models to study the Merkel cell-neurite complex and reported that mechanical stimulation, similar to gentle touch, can induce molecular changes that are potentially relevant to hair growth, thus contributing to the understanding of its underlying mechanisms.

This review examined the role of organoid technology in modeling genetic diseases, highlighting its promise for understanding disease pathology and developing tailored treatments by integrating genetic insights with advancements in regenerative medicine and biological engineering.

This review discusses the heterogeneity of dermal fibroblasts in healthy mouse and human skin and reports no clinical results; the authors highlight potential insights into physiological and pathological wound healing.

Matriptase is crucial for skin barrier, hair growth, and may contribute to skin cancer.

This study suggests that human skin contains distinct fibroblast subsets with unique expression profiles and functions, which can be isolated to investigate their role in skin pathogenesis.

This study highlights the clinical potential of microneedles as an innovative transdermal drug delivery system for treating various skin diseases with minimal pain and high patient compliance.

This review examines recent developments in tooth regeneration therapies using mesenchymal stem cells, but it reports no new clinical findings.