37 citations,
September 2018 in “Journal of the American Academy of Dermatology” Ruxolitinib can help regrow hair in severe alopecia areata.
35 citations,
October 2004 in “Biology of Reproduction” PNU157706 reduced rat sperm movement and fertility without affecting offspring health.
34 citations,
December 1991 in “Annals of the New York Academy of Sciences” The conclusion is that small hair follicles cause baldness in macaques, and treatments like antiandrogens and minoxidil can prevent hair loss and promote regrowth.
33 citations,
December 2008 in “Journal of Dermatology” Adenosine lotion improves hair growth and thickness in women with hair loss.
32 citations,
December 1969 in “The Lancet” Children with marasmus have more resting hair follicles and thinner, less pigmented hair, showing long-term malnutrition.
31 citations,
July 2015 in “Clinical, Cosmetic and Investigational Dermatology” Hair restoration surgery effectively treats hair loss with natural-looking results, using techniques like stem cells and platelet-rich plasma.
29 citations,
June 2017 in “Journal of Inherited Metabolic Disease” High-content screening is useful for finding new treatments for rare diseases and has led to FDA-approved drugs.
28 citations,
September 2020 in “Pharmaceutics” 3D-printed mesoporous scaffolds show promise for personalized drug delivery with controlled release.
28 citations,
November 2018 in “Journal of structural biology” Different populations have distinct hair structures related to their ancestry.
25 citations,
April 2018 in “Electromagnetic biology and medicine” Mobile phone radiation may cause DNA damage in human ear hair follicle cells.
23 citations,
July 1989 in “Postgraduate medical journal” Spironolactone did not make hair thinner in women with excess hair growth.
18 citations,
July 2018 in “Journal of Cosmetic Dermatology” Calcipotriol plus betamethasone with microneedling works better than tacrolimus for treating vitiligo.
12 citations,
November 2020 in “Journal of Dermatological Science” Found microRNA differences in hair cells, suggesting potential treatment targets for hair loss.
12 citations,
September 2018 in “International Journal of Cosmetic Science” Palmitoyl tetrapeptide-20 may help reduce hair greying and increase melanin production.
9 citations,
October 2018 in “Journal of Cosmetic Dermatology” Isotretinoin at a low dose for three months does not significantly affect hair growth.
1 citations,
July 2005 in “Informa Healthcare eBooks” Hair follicles could be used for targeted drug delivery, with liposomal systems showing promise for this method.
1 citations,
January 2001 in “Dermatologic Surgery” Pulsed dye laser and hydrogel dressings effectively treat hypertrophic scars.
April 2022 in “Research Square (Research Square)” The combination of laser and topical steroids is more effective for treating alopecia areata than topical steroids alone.
January 2001 in “Dermatologic Surgery” The letters discussed medical tools, costs, treatment efficacy, and patient care complexities.
June 1999 in “Proceedings of SPIE” The CO₂ laser is better for hair transplantation because it causes less damage than the Ho:YAG laser.
520 citations,
February 2001 in “Journal of Clinical Investigation” VEGF helps hair grow and determines follicle size by increasing blood vessel growth.
510 citations,
August 2006 in “Endocrinology” The vitamin D receptor is involved in multiple body functions beyond calcium regulation, including immune response and rapid reactions not related to gene activity.
384 citations,
June 2005 in “Genes & development” β-catenin is essential for stem cell activation and proliferation in hair follicles.
378 citations,
November 2011 in “Human reproduction update” Experts recommend using evidence-based methods to diagnose and treat hirsutism, focusing on symptoms and underlying causes.
343 citations,
December 2008 in “Endocrine Reviews” Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.
316 citations,
June 2004 in “The journal of investigative dermatology/Journal of investigative dermatology” Microspheres about 1.5 micrometers in size can best penetrate hair follicles, potentially reaching important stem cells.
277 citations,
June 2003 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings” Epithelial-mesenchymal interactions control hair growth cycles through specific molecular signals.
264 citations,
January 2008 in “Journal of biomedical optics” Zinc oxide nanoparticles in sunscreen do not penetrate deep into the skin.
237 citations,
February 2016 in “Science Translational Medicine” The timing of when the gene Bmal1 is active affects aging and survival, with its absence during development, not adulthood, leading to premature aging.
232 citations,
January 2016 in “BMC Bioinformatics” The method can effectively extract biomedical information without needing expert annotation, performing better than previous models.