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Targeting the Smoothened receptor shows promise for treating certain cancers.

Sonidegib and vismodegib are similarly effective for advanced basal cell carcinoma, but sonidegib might have a slightly better safety profile.

Scalp basal cell carcinoma may be more aggressive and harder to treat than other types, requiring special attention and further research.

The article concludes that hair loss is a common side effect of drugs treating skin cancer by blocking the hedgehog pathway, but treatment should continue, and more selective drugs might prevent this side effect.

Vismodegib is effective for basal cell carcinoma but has severe side effects.

Looking at tissue characteristics isn't reliable for telling apart basal cell carcinoma from certain benign skin tumors.

The document concludes that side effects from Smoothened inhibitor drugs for skin cancer are reversible and can be managed with a team approach to maintain quality of life.

Understanding and managing side effects of hedgehog pathway inhibitors can improve treatment for advanced basal cell carcinoma.

Older adults have a high rate of skin cancers like basal cell carcinoma and melanoma, mainly due to UV exposure and age.

The document concludes that recent studies help tell apart desmoplastic trichoepitheliomas from other skin tumors, but more research is needed for clear differentiation.

Hedgehog pathway inhibitors used for skin cancer can cause significant hair loss, which may improve after stopping the medication.

The document concludes that there have been significant improvements in diagnosing and treating skin diseases, including melanoma, with new techniques and therapies.

The book details skin conditions in older adults, their link to mental health, cancer treatment importance, hair loss remedies, and managing autoimmune and itchy skin.

The Hedgehog signaling pathway is important for skin and hair growth and can lead to cancer if it doesn't work right.

Hedgehog pathway inhibitors can treat certain aggressive cancers but face limitations like resistance and side effects.

Targeted cancer therapies often cause skin reactions, so dermatologists must manage these effects.

Skin aging is a complex process influenced by various factors, leading to wrinkles and sagging, and should be considered a disease due to its health impacts.

HIV can cause various severe or unusual skin conditions that help indicate the presence and stage of the disease.

A woman's hair turned white after taking a cancer drug called dasatinib.

New cancer treatments are less harmful to hair but can still cause hair loss, color, shape, and growth changes.

Modern skin cancer treatments can cause skin side effects and hair loss, affecting patients' quality of life.

The document concludes that various dermatological treatments and drugs can cause skin reactions and side effects.

Targeted cancer therapies often cause skin side effects, needing dermatologist care.

The document explains different hair loss types and treatments, emphasizing diagnosis through examination and tests, and specific treatments for each condition.

New treatments targeting the Hedgehog pathway can help treat advanced skin cancer but may have side effects and their effectiveness in early stages is unknown.

The document concludes that individualized treatment for malignant epithelial tumors is necessary and more research on metastatic squamous cell carcinoma treatments is needed.

Targeted therapy for skin cancer is complex due to the role of the hedgehog pathway in both cancer and hair growth.

The topical inhibitor CUR61414 was not effective in treating basal cell carcinoma in human trials.

The treatment was ineffective in humans.

Higher levels of nidogen1 and type IV collagen are found in basal cell carcinoma compared to normal skin.