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The document concludes that managing PCOS involves treating symptoms, regulating periods, and reducing health risks, with specific medications for fertility and metabolic issues.

Copper treatments increase copper in all tissues, but brindled female mice accumulate much more copper in their kidneys without clinical effects, unlike brindled male mice where brain copper deficiency is clinically significant.

Biotin deficiency is not a major cause of hair loss in women, so biotin supplements are not likely to be an effective hair loss treatment.

Menopausal women have higher androgen levels, which can cause symptoms like facial hair growth and low sexual desire.

Testosterone therapy aims to treat hormone deficiencies and various conditions safely and effectively, but requires careful patient monitoring due to potential side effects.

Changing the diet of mice lacking the enzyme CBS can affect symptoms related to the genetic condition.

Women with nonclassic congenital adrenal hyperplasia experience more sexual dysfunction and distress.

New genes linked to ichthyosis were found, but there's still no cure; treatment options are improving.

Low serum ferritin levels are not closely linked to telogen effluvium in women.

Over one-third of women experience hair loss, with female-pattern hair loss being most common, and treatments include minoxidil and possibly hair transplantation.

Patients with chronic renal failure on hemodialysis often have skin problems like dry skin, itching, and nail changes.

Taking oral testosterone with or without dutasteride increases testosterone levels and could be an effective treatment for low testosterone.

Adult mice with CBS deficiency show minimal health issues and normal lifespan despite high homocysteine levels.

Balding and low testosterone increase risk of urinary stones.

Testosterone replacement may help postmenopausal women with sexual function and bone density, but suitable treatments are limited.

Biotin supplements can improve certain skin disorders and hair loss when a deficiency is present.

Zinc is essential for many body functions and imbalances can lead to health problems.

Low iron levels may be linked to hair loss in women with chronic telogen effluvium.

Low iron levels are strongly linked to chronic hair loss in women.

Women with PCOS are more vulnerable to severe COVID-19 and related health issues.

Trichotillomania is a chronic hair-pulling disorder, more common in females, treated with therapy and sometimes medication.

Eating the right foods is important for skin health and can help treat some skin conditions.

Lab tests for female hair loss have unclear usefulness; consider based on symptoms.

Polycystic Ovary Syndrome should be seen mainly as a condition of excess male hormones, with a focus on this in its definition.

The report concludes that PCOS is mainly a condition of excess male hormones and its definition may change as new information is discovered.

PCOS is a complex condition with major health impacts, needing more research for better diagnosis and treatment.

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

Cushing's syndrome can cause serious health problems, and early treatment is crucial, but some issues may remain after treatment.

The guide recommends specific methods for diagnosing PCOS and various treatments for its symptoms, while considering the health impacts on adolescents.

Women with PCOS often have more belly fat and higher insulin levels, but belly fat isn't the only cause of their insulin resistance.