Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

In this study, researchers identified significant signals indicating previously unrecognized risks of lipid metabolism abnormalities for several drugs, urging the need for better monitoring and label updates.

The researchers reported that in a mouse model of alopecia areata, tofacitinib treatment influenced disease progression by modulating CD8⁺ T cell infiltration through the linoleic acid metabolism and magnesium ion pathway, offering insights into potential treatment approaches.

This study found that tofacitinib may inhibit CD8+ T cell infiltration in alopecia areata by affecting the linoleic acid metabolism-Mg2+ pathway in a sodium sulfide-induced mouse model, highlighting new insights for clinical diagnosis and treatment strategies.

This study found that in a mouse model of alopecia areata, tofacitinib inhibited CD8+ T cell infiltration at hair follicles by modulating linoleic acid metabolism and magnesium pathways, offering insights into potential therapeutic strategies for the condition.

This study revealed that tofacitinib may inhibit CD8⁺ T cell infiltration in alopecia areata by modulating the linoleic acid metabolism-Mg²⁺ pathway, providing new insights for potential treatments and diagnosis.

This study investigated alopecia areata in a mouse model, finding that tofacitinib may inhibit disease progression by modulating linoleic acid metabolism and magnesium pathways, particularly affecting CD8+ T cell infiltration in hair follicles, offering insights for potential treatments.

This study found that VDR polymorphisms, particularly ApaI and FokI variants, are associated with hormonal and metabolic disturbances in women with PCOS, with notable variations across different ethnicities.

Vitamin D deficiency is common in women with PCOS and linked to some metabolic problems, but not the main cause of their metabolic issues.

This review discusses how women with PCOS have an increased risk of insulin resistance and cardiometabolic features regardless of body fat, and calls for targeted prevention and management strategies.

This review found that lifestyle changes, such as diet and exercise, are beneficial for managing metabolic and endocrine abnormalities in obese patients with PCOS and suggests combining these with anti-obesity agents for enhanced effects.

The researchers reported that among Mediterranean Sicilian women with PCOS, Phenotype B exhibited the most severe metabolic abnormalities, notably obesity and altered glucose metabolism, whereas Phenotype D showed no such issues.

This study found that normal ALT levels in women of reproductive age are linked with metabolic and androgenic abnormalities, suggesting ALT could be used beyond liver disease diagnoses.

This systematic review observed that most studies found a higher prevalence of metabolic syndrome in women with female androgenetic alopecia, suggesting it may be a marker for metabolic abnormalities and cardiovascular risk, though some regional studies reported no significant association.

This study in North India found that patients with alopecia areata have significantly higher levels of coagulation markers, metabolic dysregulation, and systemic inflammation compared to healthy controls, and these factors are linked with disease severity, indicating potential systemic implications beyond localized hair loss.

This study found that metabolic syndrome is more common in individuals with androgenic alopecia compared to those without, and that free androgen index could help identify those with the syndrome.

Mutations in Far2 mice cause hair loss due to sebaceous gland issues.

This article reviews the clinical complications and increased mortality risks associated with Cushing's syndrome but does not present new clinical data; it emphasizes the need for prompt treatment to mitigate these risks.

This review discusses the diagnostic criteria and management strategies for Polycystic Ovary Syndrome (PCOS) and highlights the need for comprehensive clinical assessment, but does not report new clinical findings.

This study proposes reclassifying PCOS into two distinct phenotypes based on androgen levels and suggests androgen supplementation may overcome IVF resistance in one group with advancing age.

This study found that among reproductive-age women across India, there was a high prevalence of PCOS, with phenotype C being predominant and most women exhibiting metabolic abnormalities, highlighting the importance of integrating PCOS management into national health strategies.

This review discusses the challenges in diagnosing polycystic ovary syndrome in adolescents and reports no clinical results; the authors highlight the need for firm diagnostic criteria.

This protocol outlines a nationwide study to investigate the prevalence of metabolic and reproductive abnormalities, anxiety, and depression in Brazilian women with polycystic ovary syndrome, aiming to inform public health strategies.

This abstract provides background information on polycystic ovary syndrome and reports no new research findings.

This study found that cataracts, hair changes, short stature, and low bodyweight are key indicators for diagnosing Werner syndrome in patients under 30, differing from older age group symptoms.

This observational study conducted at Kushtia Medical College explored the socio-demographic and clinical profiles of 100 women with PCOS, highlighting that a significant number of these patients experienced infertility, dysmenorrhea, and metabolic abnormalities, suggesting a need for timely therapeutic interventions.

This article discusses the treatment options for women with polycystic ovarian syndrome and notes the need for further research to improve patient management.

This article discusses various potential causes of hair loss in women undergoing renal replacement therapy and emphasizes the importance of thorough patient evaluation, but it reports no new research findings.

Addressing biological changes in lipids, metabolism, and microbiota may help treat hair loss in young Chinese females with oily scalps.

This study provides an updated systematic review and meta-analysis showing that alopecia areata is associated with significantly higher odds of several autoimmune and metabolic comorbidities compared to healthy controls.

This study found that women with post-adolescent acne experience marked menstrual irregularities, polycystic ovaries, androgenetic alopecia, hirsutism, and metabolic syndrome, but insulin resistance and dyslipidemia may not significantly contribute to their acne's pathogenesis.