April 2023 in “Journal of Investigative Dermatology” In this systematic review, researchers found that individuals with lichen sclerosus have a higher prevalence of comorbidities like vitiligo, alopecia areata, and cardiovascular diseases compared to non-affected controls, and suggest screening all LS patients for cardiovascular risk factors and other diseases.
March 2023 in “Aesthetic Surgery Journal” This systematic review and meta-analysis found that activated platelet-rich plasma was significantly effective and safe in improving hair density and reducing hair loss in alopecia patients compared to control groups.
January 2023 in “Journal of cosmetic dermatology” This study concluded that fractional laser therapy, alone or combined with minoxidil or cortisol, effectively treated alopecia areata, showing better outcomes than the drugs alone, without increasing adverse effects, though effectiveness did not significantly differ from similar physical treatments.
January 2023 in “Dermatologic therapy” This study reports that diphenylcyclopropenone topical immunotherapy resulted in any hair regrowth for 69% of patients with alopecia areata, but with common side effects including mild to severe contact dermatitis.
September 2022 in “Research Square (Research Square)” This study found that while pro-, pre-, and synbiotics may have beneficial effects on certain PCOS-related outcomes, the certainty of this evidence is low to very low.
September 2022 in “Journal of The American Academy of Dermatology” This review summarizes existing literature on COVID-19-associated alopecia, finding that androgenic alopecia may increase COVID-19 risk, while telogen effluvium often follows infection.
This study found that platelet-rich plasma injections significantly improved hair density in male patients with androgenetic alopecia compared to placebo treatments.
December 2021 in “Dermatology research” This study found that individuals with premature graying of hair had significantly lower serum levels of vitamin B12, ferritin, and calcium compared to those without premature graying.
This study suggests that autologous platelet-rich plasma injections may increase terminal hair density in women with androgenetic alopecia, without significantly affecting hair thickness.
This study found that women with nonscarring alopecia had significantly lower ferritin levels compared to women without the condition.
August 2020 in “Universidad Peruana de Ciencias Aplicadas (UPC)” This study found that platelet-rich plasma appeared more effective than control treatments as an additional therapy for improving acne scars in several clinical trials.
This study investigates whether adding 30% supramolecular salicylic acid to conventional treatment for mild to moderate acne vulgaris is safe and effective, though specific results are not reported in the abstract.
April 2019 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” This study identified three new genetic loci associated with PCOS and found a similar genetic structure across different diagnostic criteria, suggesting a genetic basis for shared metabolic traits and potential causal links to other conditions.
January 2019 in “프로그램북(구 초록집)” This study reported that oral JAK inhibitors, tofacitinib and ruxolitinib, may effectively promote hair regrowth in alopecia areata patients, though ruxolitinib had fewer adverse events compared to tofacitinib.
December 2018 in “UNIFESP Institutional Repository (Universidade Federal de São Paulo)” This review updated the evidence on various treatments for alopecia areata, finding that minoxidil and high potency corticosteroids showed significant results in patchy AA, but the overall evidence quality was low.
This review investigates whether combining microneedling with minoxidil is more effective than using minoxidil alone for increasing hair density and diameter in patients with alopecia. Results are not reported.
December 2022 in “Plastic and Reconstructive Surgery” This study found that autologous platelet-rich plasma significantly improved hair follicle number, thickness, and density in patients with androgenic alopecia compared to placebo, with high reported patient satisfaction.
The systematic review and meta-analysis evaluated the efficacy and safety of combining microneedling therapy with other treatments for androgenic alopecia. The analysis included multiple randomized clinical trials, providing a comprehensive assessment of the combined treatment approach. The findings suggested that microneedling, when used in conjunction with other therapies, improved hair growth outcomes in patients with androgenic alopecia. The study also reported that the combined treatment was generally safe, with no significant adverse effects noted. However, as the review was completed but not published, the detailed results and specific number of participants involved in the trials were not disclosed.
October 2022 in “Journal of Dermatological Treatment” This study found that autologous platelet-rich plasma injections may improve terminal hair density in women with androgenetic alopecia, but did not significantly affect hair thickness.
October 2022 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” 
January 2022 in “Surgical and Cosmetic Dermatology” This study found a significant correlation between androgenic alopecia and metabolic syndrome, suggesting individuals with alopecia have higher odds of metabolic syndrome.
April 2015 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” The safety of the hair loss drug finasteride is unclear due to inadequate reporting in clinical trials.
This study found that vertex pattern androgenetic alopecia was significantly associated with an increased risk of prostate cancer, whereas any pattern of the condition did not show a significant risk increase.
October 2011 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” Certain gene variations are significantly linked to hair loss, especially in white people.
5 citations
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May 2018 in “Journal of the American Academy of Dermatology” This study found no significant correlation between vitamin D levels and disease severity in alopecia areata patients, highlighting the need for further research on vitamin D supplementation's effects.
4 citations
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October 2023 in “Dermatology” In this study, a network meta-analysis found that treating lichen planopilaris with a combination of clobetasol, hydroxychloroquine, and N-acetylcysteine was the most effective approach, while cyclosporine, methotrexate, and some other treatments were less effective compared to hydroxychloroquine.
2 citations
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January 2022 in “Skin appendage disorders” This study found that for people with androgenetic alopecia, increasing the dosage of low-dose oral minoxidil is associated with improvements in hair diameter and density, but also raises the risk of hypertrichosis and cardiovascular adverse events.
150 citations
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February 2008 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” This study suggests that antiandrogens may slightly reduce hirsutism severity compared to placebo, but evidence is weak and their relative efficacy remains uncertain.
67 citations
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March 2018 in “The Journal of Clinical Endocrinology & Metabolism” This study reported that estrogen-progestin oral contraceptives, antiandrogens, and insulin sensitizers are more effective than placebo in treating hirsutism in women, with combination therapies generally proving superior to monotherapy.
63 citations
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January 2012 in “The European Journal of Contraception & Reproductive Health Care” This study concluded that combined hormonal contraceptives containing desogestrel, drospirenone, or cyproterone acetate were associated with a higher risk of venous thromboembolism compared to those containing levonorgestrel.