39 citations,
March 2022 in “Nature Protocols” Scientists created hair-growing skin models from stem cells, which could help treat hair loss and skin diseases.
7 citations,
May 2020 in “Trends in molecular medicine” The document concludes that the immune-inhibitory environment of the hair follicle may prevent melanoma development.
86 citations,
June 2017 in “Stem cell investigation” Stem cells from hair follicles can safely treat hair loss.
May 2022 in “Frontiers in Cell and Developmental Biology” miR-29a-5p prevents the formation of early hair structures by targeting a gene important for hair growth and is regulated by a complex network involving lncRNA627.1.
February 2014 in “Journal of The American Academy of Dermatology”
276 citations,
December 2017 in “Journal of Dermatological Science” The document concludes that mouse models are helpful but have limitations for skin wound healing research, and suggests using larger animals and genetically modified mice for better human application.
67 citations,
July 2016 in “Reviews in Endocrine and Metabolic Disorders” Stress can worsen skin conditions by affecting hormone levels and immune response.
September 1999 in “The Journal of The British Menopause Society” The document concludes that skin aging in women can be caused by UV exposure and hormonal changes, and treatments like hormone replacement therapy and various skin therapies can help.
122 citations,
July 2005 in “The FASEB journal” Hair follicles produce and respond to melatonin, affecting hair growth and sensitivity to estrogen.
84 citations,
June 2013 in “Stem Cells Translational Medicine” New methods for skin and nerve regeneration can improve healing and feeling after burns.
66 citations,
May 2012 in “Scientific Reports” Scientists successfully created and transplanted bioengineered hair follicles that function like natural ones, suggesting a new treatment for hair loss.
49 citations,
August 2004 in “The FASEB Journal” Mice with human skin protein K8 had more skin problems and cancer.
29 citations,
September 2012 in “Birth Defects Research” Wounds heal without scarring in early development but later result in scars, and studying Wnt signaling could help control scarring.
16 citations,
July 2021 in “Histopathology” New markers and pathways have been found in skin tumors, helping better understand and diagnose them.
13 citations,
March 2012 in “The Journal of Dermatology” Hair transplant surgery can rebuild muscle and nerve connections, allowing transplanted hairs to stand up like normal hairs.
9 citations,
July 2017 in “Journal of medical case reports” Ruxolitinib treatment may cause eyelash growth.
1 citations,
January 2009 in “Elsevier eBooks” The document concludes that a deeper understanding of skin aging and photodamage is needed to create better skin treatments.
January 2024 in “Archives of pharmacy practice” The skin is vital for protection, temperature control, fluid balance, immunity, and sensing, with damage affecting daily life and mental health.
January 2022 in “International Journal of Biology Pharmacy and Allied Sciences” Autoimmune diseases cause the immune system to attack the body, and management varies as some are curable and others are not.
December 2021 in “International Journal of Biology Pharmacy and Allied Sciences” Autoimmune diseases cause the immune system to attack the body, and management varies as some are curable and others are not.
June 2021 in “Scholars journal of applied medical sciences” Trichofolliculoma, a rare benign hair follicle tumor, can potentially recur.
275 citations,
March 1999 in “Journal of The American Academy of Dermatology” Chemotherapy can cause various skin reactions, with hair loss being the most common, and proper diagnosis and treatment of these reactions are important.
263 citations,
February 2013 in “Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology” Polymeric nanoparticles show promise for treating skin diseases.
168 citations,
August 2000 in “American Journal of Pathology” Fibromodulin might help reduce scarring if increased in adult wounds like in fetal skin that heals without scars.
162 citations,
August 2002 in “Survey of Ophthalmology” Latanoprost can make eyelashes longer, thicker, and darker.
77 citations,
December 2010 in “The journal of investigative dermatology/Journal of investigative dermatology” Human skin cells produce proenkephalin, which changes with environmental factors and skin diseases.
70 citations,
October 2020 in “The journal of allergy and clinical immunology/Journal of allergy and clinical immunology/The journal of allergy and clinical immunology” Janus kinase inhibitors are promising drugs for treating autoimmune and inflammatory diseases.
69 citations,
September 1991 in “Journal of Surgical Research” Understanding how fetal wounds heal could help improve healing in adults.
39 citations,
October 2014 in “Schweizerische medizinische Wochenschrift” Cyclophosphamide has serious side effects, but long-term follow-up can help manage risks.
32 citations,
December 2017 in “International Journal of Molecular Sciences” Low vitamin D might be linked to certain types of hair loss, and supplements could help, but more research is needed.