January 2012 in “Journal für Kardiologie (Krause & Pachernegg GmbH)” This article discusses the role of androgens in skin conditions like acne and alopecia, emphasizing combined systemic and topical therapy approaches, but it reports no new clinical outcomes.
137 citations
,
June 2005 in “Climacteric” This review indicates that estrogen loss during menopause significantly impacts skin health, while estrogen treatment may increase skin collagen, thickness, and elasticity, though effects on other skin characteristics are inconsistent.
July 1989 in “British Journal of Dermatology” Minoxidil helps increase hair growth and density in people with hair loss, with higher concentrations giving better results.
82 citations
,
January 2000 in “Hormone Research in Paediatrics” This study describes the enzymatic processes through which DHEA is converted to active sex steroids in human skin, highlighting an androgenic effect on sebaceous glands and estrogenic effects in the vagina.
46 citations
,
May 2009 in “Maturitas” This study found that taking a daily oral dose of 50mg DHEA for one year had no significant impact on blood lipids, insulin sensitivity, or the endometrium in postmenopausal women with low libido.
46 citations
,
January 2008 in “Climacteric” Randomized trials reported that testosterone therapy improved sexual function in postmenopausal women with hypoactive sexual desire disorder, particularly those who had undergone oophorectomy, with reversible and well-tolerated side effects.
10 citations
,
April 2006 in “Seminars in Reproductive Medicine” This article reviews the limited evidence on testosterone therapy for premenopausal women and notes a lack of long-term safety and effectiveness data for this population.
9 citations
,
November 2016 in “Journal of medical science and clinical research” In this study, the prevalence of clinical polycystic ovary syndrome among high school girls in Sambalpur, Odisha, was found to be 12%.
4 citations
,
January 2024 in “International Journal of Environment Agriculture and Biotechnology” This article discusses polycystic ovary syndrome (PCOS) and its complex symptoms, highlighting treatment strategies focused on managing symptoms and reducing complications but reports no new clinical findings.
2 citations
,
March 2016 in “InnovAiT” This article discusses the signs, symptoms, and associated risks of polycystic ovary syndrome, without providing new clinical results; it emphasizes the link between being overweight and increased metabolic risks.
1 citations
,
September 2016 in “Springer eBooks” This article reports no new data; it describes the role of sebum in influencing the skin microbiome and epithelial tissues and discusses its altered composition during transit through the sebaceous duct.
January 2026 in “Clinics in Dermatology” This discussion examines the aesthetic symptoms of perimenopause, such as hot flashes and skin changes, and reviews management options like hormone replacement therapy and topical cosmetics, emphasizing the importance of consistency in treatment to maintain results.
October 2025 in “World Journal of Biology Pharmacy and Health Sciences” This review highlights the role of sex hormones in skin health, observing that hormonal changes throughout a woman's life can affect skin conditions such as acne and hair loss, with treatments involving hormonal therapies and the importance of a multidisciplinary approach.
October 2025 in “Zenodo (CERN European Organization for Nuclear Research)” This source reviews the influence of sex hormones on skin health, detailing how hormonal fluctuations impact dermatological conditions throughout a woman's life and highlighting the necessity for integrated dermatological, gynecological, and endocrine care alongside mental health support to address these conditions' physical and psychological effects.
October 2025 in “Zenodo (CERN European Organization for Nuclear Research)” This review describes how sex hormones like estrogens and androgens influence skin health, linking hormonal fluctuations to conditions such as acne and hair loss, and underscores the importance of a multidisciplinary approach to treatment that includes mental health support.
July 2025 in “AACE Endocrinology and Diabetes” Ovarian hyperthecosis caused high testosterone and virilization symptoms in a 60-year-old woman, which improved after surgery.
January 2019 in “ISGE series” This review discusses the criteria, diagnosis, and treatment options for polycystic ovary syndrome and reports no new clinical results; it highlights the need for further research on causative treatments.
This paper suggests that women with acne should be screened for PCOS to enable early treatment and prevent associated risk factors.
January 2003 in “Elsevier eBooks” Androgens and other hormones affect hair growth and skin conditions like acne.
April 2020 in “Journal of the Endocrine Society” This case report highlights Leydig cell hyperplasia as a rare cause of increased testosterone and postmenopausal hirsutism, resolved after bilateral salpingo-oophorectomy in a 64-year-old woman.
305 citations
,
February 2007 in “Hormone and metabolic research” This review discusses the roles of androgens and estrogens in skin functions and disorders, and highlights the use of estrogen-progestin treatments and anti-androgens in managing hirsutism and acne, without reporting new results.
164 citations
,
February 2019 in “Anais Brasileiros de Dermatologia” This study produced a guide for managing adult female acne, addressing its complex nature compared to teenage acne, and providing detailed recommendations on diagnosis and treatment. The authors noted that further research is needed to better understand the condition.
138 citations
,
May 2000 in “Maturitas” This review discusses the effects of estrogen on skin and reports no new clinical results; it highlights estrogen's potential benefits on skin thickness, collagen quality, and hair follicle life cycle.
130 citations
,
May 1988 in “Journal of The American Academy of Dermatology” This study found that frontal and frontoparietal hair recession is relatively common in women, especially after menopause, and may not indicate abnormal androgen metabolism absent other virilization signs.
81 citations
,
May 2007 in “Fertility and Sterility” This review discusses the safety of testosterone therapy for postmenopausal women and concludes that, aside from hirsutism and acne, it appears safe at physiological doses for several years, though more long-term studies are needed.
49 citations
,
February 2009 in “Maturitas” This review discusses the use of testosterone therapy for low libido in women, noting mixed evidence on breast cancer risk and a lack of long-term safety data.
26 citations
,
February 2022 in “Annals of Palliative Medicine” This study found that ultra-pulse CO2 fractional laser treatment improved skin smoothness and total skin lesion scores more effectively in patients with depressed acne scars compared to other treatments.
26 citations
,
January 2013 in “BioMed Research International” This review discusses the hormonal influences on hair cycling disorders in post-partum and postmenopausal women and notes the lack of evidence for effective targeted treatments.
17 citations
,
November 2012 in “Maturitas” This review discusses the management of hair loss in midlife women, focusing on female pattern hair loss, hair shaft alterations from hair care, and telogen effluvium, and reports no new research findings.
12 citations
,
March 2017 in “Journal of obstetrics and gynaecology Canada” This review discusses the limitations of serum androgen measurements in diagnosing and treating women with potential androgen-related disorders and the potential role of androgen replacement therapy for those with sexual interest/arousal disorders, reporting no new results.